V. Marchán

发表

Conjugation of a Ru(II) arene complex to neomycin or to guanidinoneomycin leads to compounds with differential cytotoxicities and accumulation between cancer and normal cells.

F. Barragán, V. Moreno, A. Massaguer, 2013, Molecular pharmaceutics.

Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium(II) complex.

P. Sadler, F. Barragán, V. Moreno, 2011, Journal of the American Chemical Society.

Unexpected photoactivation pathways in a folate-receptor-targeted trans-diazido Pt(iv) anticancer pro-drug.

P. Sadler, V. Marchán, Huayun Shi, 2020, Dalton transactions.

An integrin-targeted photoactivatable Pt(IV) complex as a selective anticancer pro-drug: synthesis and photoactivation studies.

P. Sadler, A. Massaguer, J. Woods, 2015, Chemical communications.

Integrin-targeted delivery into cancer cells of a Pt(IV) pro-drug through conjugation to RGD-containing peptides.

V. Moreno, S. Barrabés, A. Massaguer, 2015, Dalton transactions.

Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated Ir III Complex Conjugated to a Far‐Red Emitting Coumarin

V. Brabec, J. Kašpárková, S. Nonell, 2019, Angewandte Chemie.

Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated IrIII Complex Conjugated to a Far-Red Emitting Coumarin.

V. Brabec, J. Kašpárková, S. Nonell, 2019, Angewandte Chemie.

A versatile click chemistry-based approach for functionalizing biomaterials of diverse nature with bioactive peptides.

M. Ginebra, C. Mas-Moruno, V. Marchán, 2021, Chemical communications.

Improving Photodynamic Therapy Anticancer Activity of a Mitochondria-Targeted Coumarin Photosensitizer Using a Polyurethane–Polyurea Hybrid Nanocarrier

J. Ruiz, M. Bosch, V. Marchán, 2022, Biomacromolecules.

Stabilization of DNA duplexes by covalently-linked peptides

E. Pedroso, A. Grandas, V. Marchán, 2004 .

Towards nucleopeptides containing any trifunctional amino acid (II)

E. Pedroso, A. Grandas, J. Robles, 1999 .

AN IMPROVED SYNTHESIS OF N-[(9-HYDROXYMETHYL)-2-FLUORENYL]SUCCINAMIC ACID (HMFS), A VERSATILE HANDLE FOR THE SOLID-PHASE SYNTHESIS OF BIOMOLECULES

E. Giralt, R. Eritja, E. Pedroso, 2001 .

Solid-phase synthesis and DNA binding studies of dichloroplatinum(ii) conjugates of dicarba analogues of octreotide as new anticancer drugs.

F. Barragán, V. Moreno, V. Marchán, 2009, Chemical communications.

Solid-Phase Approaches for Labeling Targeting Peptides with Far-Red Emitting Coumarin Fluorophores.

A. Massaguer, M. Bosch, V. Marchán, 2019, The Journal of organic chemistry.

SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules

A. García-Sastre, K. White, M. Rodríguez, 2022, Pharmaceuticals.

Exploring the effect of aminoglycoside guanidinylation on ligands for Tau exon 10 splicing regulatory element RNA.

G. Artigas, Paula López-Senín, V. Marchán, 2012, Organic & biomolecular chemistry.

A simple method for the synthesis of N-difluoromethylated pyridines and 4-pyridones/quinolones by using BrCF2COOEt as the difluoromethylation reagent

V. Marchán, M. E. El Fakiri, Albert Gandioso, 2020, RSC advances.

Somatostatin receptor-targeted organometallic iridium(iii) complexes as novel theranostic agents.

V. Brabec, A. Zamora, J. Ruiz, 2017, Chemical communications.

Development of Green/Red-Absorbing Chromophores Based on a Coumarin Scaffold That Are Useful as Caging Groups.

S. Nonell, D. Velasco, Jaume Garcia-Amorós, 2017, The Journal of organic chemistry.

A Green Light-Triggerable RGD Peptide for Photocontrolled Targeted Drug Delivery: Synthesis and Photolysis Studies.

A. Massaguer, V. Marchán, Albert Gandioso, 2016, The Journal of organic chemistry.

Redesigning the Coumarin Scaffold into Small Bright Fluorophores with Far-Red to Near-Infrared Emission and Large Stokes Shifts Useful for Cell Imaging.

C. Rovira, S. Nonell, A. Nin‐Hill, 2018, The Journal of organic chemistry.

Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes.

P. Sadler, Carlos González, F. Barragán, 2012, Bioconjugate chemistry.

2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl group for 5'-hydroxyl protection of deoxyribonucleoside phosphoramidites in the solid-phase preparation of DNA oligonucleotides.

S. Beaucage, V. Marchán, J. Cieślak, 2004, Journal of the American Chemical Society.

Identification of ligands for the Tau exon 10 splicing regulatory element RNA by using dynamic combinatorial chemistry.

A. Grandas, I. Gómez-Pinto, Paula López-Senín, 2011, Chemistry.

Thermolytic carbonates for potential 5'-hydroxyl protection of deoxyribonucleosides.

S. Beaucage, M. Chmielewski, V. Marchán, 2003, Journal of Organic Chemistry.

High Photostability in Nonconventional Coumarins with Far-Red/NIR Emission through Azetidinyl Substitution.

S. Nonell, M. Bosch, V. Marchán, 2018, The Journal of organic chemistry.

Solution Structure and Stability of Tryptophan‐Containing Nucleopeptide Duplexes

Carlos González, F. Gago, A. Grandas, 2003, Chembiochem : a European journal of chemical biology.

Thermolytic Carbonates for Potential 5′‐Hydroxyl Protection of Deoxyribonucleosides.

S. Beaucage, M. Chmielewski, V. Marchán, 2004 .

Conceptual “Heat‐Driven” Approach to the Synthesis of DNA Oligonucleotides on Microarrays

S. Beaucage, L. Phillips, V. Marchán, 2003, Annals of the New York Academy of Sciences.

Alternative Procedures for the Synthesis of Methionine‐Containing Peptide−Oligonucleotide Hybrids

E. Pedroso, A. Grandas, C. Rodríguez-Tanty, 2000 .

Stepwise Solid‐Phase Synthesis of Nucleopeptides

E. Pedroso, A. Grandas, V. Marchán, 2004, Current protocols in nucleic acid chemistry.

Stepwise Solid‐Phase Synthesis of Nucleopeptides

E. Pedroso, A. Grandas, V. Marchán, 2004 .

Fluorescently Labeled Ceramides and 1-Deoxyceramides: Synthesis, Characterization, and Cellular Distribution Studies

G. Fabriàs, J. Abad, M. Bosch, 2022, The Journal of organic chemistry.

Synthesis of Janus compounds for the recognition of G-U mismatched nucleobase pairs.

G. Artigas, V. Marchán, 2013, The Journal of organic chemistry.

Efficient siRNA-peptide conjugation for specific targeted delivery into tumor cells.

M. Orozco, I. Brun-Heath, A. Massaguer, 2017, Chemical communications.

A Photoactivatable Platinum(IV) Anticancer Complex Conjugated to the RNA Ligand Guanidinoneomycin.

P. Sadler, G. Clarkson, A. Massaguer, 2015, Chemistry.

A Cyclometalated IrIII Complex Conjugated to a Coumarin Derivative Is a Potent Photodynamic Agent against Prostate Differentiated and Tumorigenic Cancer Stem Cells.

V. Brabec, J. Kašpárková, H. Kostrhunova, 2021, Chemistry.

Sequential Uncaging with Green Light can be Achieved by Fine‐Tuning the Structure of a Dicyanocoumarin Chromophore

C. Rovira, S. Nonell, A. Nin‐Hill, 2017, ChemistryOpen.

Transformation of COUPY fluorophores into a novel class of visible light-cleavable photolabile protecting groups.

S. Nonell, M. Bosch, V. Marchán, 2020, Chemistry.

Toward Angiogenesis Inhibitors Based on the Conjugation of Organometallic Platinum(II) Complexes to RGD Peptides

C. Calvis, F. Mitjans, A. Massaguer, 2018, ChemMedChem.

Linking the 3′ Ends of Oligonucleotide Duplexes with Cystine Disulfide Bridges

E. Pedroso, A. Grandas, Daniel Pulido, 2006 .

Selective platination of modified oligonucleotides and duplex cross-links.

E. Pedroso, A. Grandas, V. Marchán, 2006, Angewandte Chemie.

Insights into the reaction of transplatin with DNA and proteins: methionine-mediated formation of histidine-guanine trans-Pt(NH3)2 cross-links.

E. Pedroso, A. Grandas, V. Marchán, 2004, Chemistry.

COUPY Coumarins as Novel Mitochondria-Targeted Photodynamic Therapy Anticancer Agents

J. Ruiz, M. Bosch, V. Marchán, 2021, Journal of medicinal chemistry.

Towards a better understanding of the cisplatin mode of action.

E. Pedroso, V. Moreno, A. Grandas, 2001, Chemistry.

Incorporation of two modified nucleosides allows selective platination of an oligonucleotide making it suitable for duplex cross-linking

E. Pedroso, A. Grandas, V. Marchán, 2007, JBIC Journal of Biological Inorganic Chemistry.

Synthesis and tau RNA binding evaluation of ametantrone-containing ligands.

G. Artigas, V. Marchán, 2015, The Journal of organic chemistry.

Ametantrone-based compounds as potential regulators of Tau pre-mRNA alternative splicing.

N. Escaja, G. Artigas, Paula López-Senín, 2015, Organic & biomolecular chemistry.

Multivariate curve resolution applied to the analysis and resolution of two-dimensional [1H,15N] NMR reaction spectra.

Romà Tauler, Raimundo Gargallo, Joaquim Jaumot, 2004, Analytical chemistry.

Preparation of ribonuclease S domain-swapped dimers conjugated with DNA and PNA: modulating the activity of ribonucleases.

D. Laurents, A. Grandas, Daniel Pulido, 2008, Bioconjugate chemistry.

Exploring Structure–Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates

S. Nonell, Cormac Hally, J. Ruiz, 2023, Journal of medicinal chemistry.

Solution structure and stability of a disulfide cross-linked nucleopeptide duplex.

F. Gago, A. Grandas, I. Gómez-Pinto, 2003, Chemical communications.

Diels-Alder cycloadditions in water for the straightforward preparation of peptide–oligonucleotide conjugates

E. Pedroso, A. Grandas, Daniel Pulido, 2006, Nucleic Acids Research.

Mitochondria-Targeted COUPY Photocages: Synthesis and Visible-Light Photoactivation in Living Cells

S. Nonell, M. Bosch, V. Marchán, 2023, The Journal of organic chemistry.

Synthesis of Peptide‐Oligonucleotide Conjugates by Diels‐Alder Cycloaddition in Water

A. Grandas, V. Marchán, 2007, Current protocols in nucleic acid chemistry.