Yoshitaka Hiruma

发表

Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinase

R. Joosten, A. Perrakis, A. Koch, 2016, Proteins.

Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling

M. Ubbink, G. Kops, A. Perrakis, 2015, Science.

The structure of the cytochrome p450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography.

Wei-Min Liu, H. Schwalbe, F. Löhr, 2013, Journal of molecular biology.

Modulation of protein–ligand interactions by photocleavage of a cyclic peptide using phosphatidylinositol 3‐kinase SH3 domain as model system

M. Ubbink, S. Hirota, N. Okishio, 2009, Journal of peptide science : an official publication of the European Peptide Society.

Design, synthesis, and evaluation of a lanthanide chelating protein probe: CLaNP-5 yields predictable paramagnetic effects independent of environment.

P. Keizers, M. Ubbink, M. Overhand, 2008, Journal of the American Chemical Society.

Validation of a lanthanide tag for the analysis of protein dynamics by paramagnetic NMR spectroscopy.

P. Keizers, M. Ubbink, Anneloes J. Blok, 2010, Journal of the American Chemical Society.

The MPS1 kinase NTE region has helical propensity and preferred conformations towards the TPR domain

Wouter G. Touw, M. Ubbink, G. Kops, 2020, bioRxiv.

Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing.

G. Kops, A. Perrakis, E. Tromer, 2019, Cell reports.

Hot‐Spot Residues in the Cytochrome P450cam–Putidaredoxin Binding Interface

M. Ubbink, A. Gupta, Yoshitaka Hiruma, 2014, Chembiochem : a European journal of chemical biology.

The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage.

J. Abrahams, G. Lippens, A. Gräslund, 2018, Journal of the American Chemical Society.

A solution model of the complex formed by adrenodoxin and adrenodoxin reductase determined by paramagnetic NMR spectroscopy.

P. Keizers, M. Ubbink, J. Donauer, 2010, Biochemistry.

Delicate conformational balance of the redox enzyme cytochrome P450cam

Wei-Min Liu, M. Ubbink, Anneloes J. Blok, 2015, Proceedings of the National Academy of Sciences.

Protein–Paramagnetic Protein Interactions

P. Keizers, M. Ubbink, Yoshitaka Hiruma, 2012 .

LAHMA: structure analysis through local annotation of homology-matched amino acids

R. Joosten, M. Hekkelman, A. Perrakis, 2021, Acta crystallographica. Section D, Structural biology.

Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures

R. Medema, R. Joosten, A. Perrakis, 2017, The Journal of Biological Chemistry.

Endogenous polyamines reduce the toxicity of soluble aβ peptide aggregates associated with Alzheimer's disease.

J. Abrahams, A. Gräslund, Jinghui Luo, 2014, Biomacromolecules.

Identification of productive and futile encounters in an electron transfer protein complex

C. Luchinat, M. Ubbink, E. Ravera, 2017, Proceedings of the National Academy of Sciences.

Interactions between N-Terminal Modules in MPS1 Enable Spindle Checkpoint Silencing

G. Kops, A. Perrakis, Yoshitaka Hiruma, 2018, bioRxiv.

Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling

M. Ubbink, G. Kops, A. Perrakis, 2015, Science.

Design, synthesis, and evaluation of a lanthanide chelating protein probe: CLaNP-5 yields predictable paramagnetic effects independent of environment.

P. Keizers, M. Ubbink, M. Overhand, 2008, Journal of the American Chemical Society.

Modulation of protein–ligand interactions by photocleavage of a cyclic peptide using phosphatidylinositol 3‐kinase SH3 domain as model system

M. Ubbink, S. Hirota, N. Okishio, 2009, Journal of Peptide Science.