Yuji Sato

发表

Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.

Yusuke Nakamura, H. Yoshida, K. Kusakabe, 2015, Journal of medicinal chemistry.

A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.

Yusuke Nakamura, K. Kusakabe, Y. Daigo, 2015, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1.

K. Hino, S. Kashimoto, Yuji Sato, 2002, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of 3-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridines as novel antitumor agents.

S. Kashimoto, Yuji Sato, K. Chiba, 2004, Bioorganic & medicinal chemistry letters.

Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models

U. Hoch, S. Kashimoto, J. Silverman, 2009, Cancer Chemotherapy and Pharmacology.

Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively

Kazunari Hattori, Hideki Yamamoto, A. Kikuchi, 2015, Scientific Reports.

Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation.

Yusuke Nakamura, Takayuki Kanazawa, Kazuo Ueda, 2012, ACS medicinal chemistry letters.

Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).

Yusuke Nakamura, K. Kusakabe, Y. Daigo, 2013, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 2.

S. Kashimoto, Yuji Sato, K. Chiba, 2004, Journal of medicinal chemistry.