M. Higaki

Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.

Yusuke Nakamura, H. Yoshida, K. Kusakabe, 2015, Journal of medicinal chemistry.

A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.

Yusuke Nakamura, K. Kusakabe, Y. Daigo, 2015, Bioorganic & medicinal chemistry.

Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation.

Yusuke Nakamura, Takayuki Kanazawa, Kazuo Ueda, 2012, ACS medicinal chemistry letters.

Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).

Yusuke Nakamura, K. Kusakabe, Y. Daigo, 2013, Journal of medicinal chemistry.