C. A. de Simone

发表

Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice.

R. S. Ferreira, J. McKerrow, C. Meira, 2012, Bioorganic & medicinal chemistry.

2-(Phenylcarbonothioylsulfanyl)acetic acid

Chang-Ge Zheng, Jian-Quan Hong, Jie Zhang, 2010, Acta crystallographica. Section E, Structure reports online.

Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives.

Mariano A. Pereira, E. Barreiro, C. Fraga, 2009, European journal of medicinal chemistry.

Carbon nanotube–ruthenium hybrid towards mild oxidation of sulfides to sulfones: efficient synthesis of diverse sulfonyl compounds

E. Doris, R. S. Gomes, E. Gravel, 2019, Catalysis Science & Technology.

On the synthesis, optical and computational studies of novel BODIPY-based phosphoramidate fluorescent dyes

F. Emery, C. A. de Simone, E. N. da Silva Júnior, 2019, Journal of Fluorine Chemistry.

Quinone-Derived π-Extended Phenazines as New Fluorogenic Probes for Live-Cell Imaging of Lipid Droplets

M. Vendrell, Fabio de Moliner, Gleiston G. Dias, 2018, Front. Chem..

Design of hybrid molecules as antimycobacterial compounds: Synthesis of isoniazid-naphthoquinone derivatives and their activity against susceptible and resistant strains of Mycobacterium tuberculosis.

D. Ramos, P. Halicki, P. E. Almeida da Silva, 2019, Bioorganic & medicinal chemistry.

Potential of a metal-organic framework as a new material for solid-phase extraction of pesticides from lettuce (Lactuca sativa), with analysis by gas chromatography-mass spectrometry.

M. O. Rodrigues, S. Junior, G. F. de Sá, 2010, Journal of separation science.

Quinonoid compounds via reactions of lawsone and 2-aminonaphthoquinone with α-bromonitroalkenes and nitroallylic acetates: Structural diversity by C-ring modification and cytotoxic evaluation against cancer cells.

I. Namboothiri, B. Cavalcanti, T. V. Baiju, 2018, European journal of medicinal chemistry.

Structural design, synthesis and pharmacological evaluation of 4-thiazolidinones against Trypanosoma cruzi.

R. S. Ferreira, C. Meira, M. Soares, 2015, Bioorganic & medicinal chemistry.

Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.

R. S. Ferreira, R. Srivastava, C. Meira, 2012, Journal of medicinal chemistry.

On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.

A. S. de Araujo, Marcelo dos Santos, F. Emery, 2012, European journal of medicinal chemistry.

The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles.

C. K. Andrade, B. Cavalcanti, R. S. Menna-Barreto, 2010, Bioorganic & medicinal chemistry.

4-Formyl-2-nitrophenyl 4-bromobenzoate

J. Ellena, C. A. de Simone, R. Moreno-Fuquen, 2013, Acta crystallographica. Section E, Structure reports online.

Synthesis and evaluation of quinonoid compounds against tumor cell lines.

L. Costa-Lotufo, B. Cavalcanti, Marcelo dos Santos, 2011, European journal of medicinal chemistry.

2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile

S. Galdino, I. Pitta, M. D. de Lima, 2011, Acta crystallographica. Section E, Structure reports online.

Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.

V. Ferreira, R. S. Silva, R. S. Menna-Barreto, 2008, European journal of medicinal chemistry.

Synthesis of naphthofuranquinones with activity against Trypanosoma cruzi.

R. S. Silva, S. D. de Castro, A. V. Pinto, 2006, European journal of medicinal chemistry.

1,3-Azoles from ortho-naphthoquinones: synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosis.

P. A. D. da Silva, P. F. Carneiro, M. C. Pinto, 2012, Bioorganic & medicinal chemistry.

Quinonoid and phenazine compounds: synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis.

B. Cavalcanti, P. A. D. da Silva, P. F. Carneiro, 2011, European journal of medicinal chemistry.

Synthesis, Structure-Activity Relationships (SAR) and in Silico Studies of Coumarin Derivatives with Antifungal Activity

M. Scotti, L. Scotti, J. Barbosa-Filho, 2013, International journal of molecular sciences.

Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.

R. S. Ferreira, A. C. da Silva, V. Pereira, 2014, European journal of medicinal chemistry.

Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights.

Divya K. Nair, D. Boothman, I. Namboothiri, 2016, European journal of medicinal chemistry.

1-Benzyl-2,5-dioxopyrrolidine-3,4-diyl diacetate

E. Tiekink, H. A. Stefani, I. Caracelli, 2010, Acta crystallographica. Section E, Structure reports online.

5-Chloroquinolin-8-yl furan-2-carboxylate

J. Ellena, C. A. de Simone, R. Moreno-Fuquen, 2013, Acta crystallographica. Section E, Structure reports online.

3-arylamino and 3-alkoxy-nor-beta-lapachone derivatives: synthesis and cytotoxicity against cancer cell lines.

C. K. Andrade, B. Cavalcanti, V. Ferreira, 2010, Journal of medicinal chemistry.

Synthesis of quinone imine and sulphur-containing compounds with antitumor and trypanocidal activities: redox and biological implications.

Carlos R K Paier, Ammar Kharma, C. Pessoa, 2020, RSC medicinal chemistry.

Redetermination of 4-cyanopyridine N-oxide

C. A. de Simone, R. Moreno-Fuquen, C. Arana, 2012, Acta crystallographica. Section E, Structure reports online.

Antimony(V) and Bismuth(V) Complexes of Lapachol: Synthesis, Crystal Structure and Cytotoxic Activity

F. Frézard, C. Demicheli, E. Pereira-Maia, 2011, Molecules.

cis-Bis{1,1-dibenzyl-3-[(furan-2-yl)carbonyl]thioureato-κ2 O,S}nickel(II)

J. Ellena, C. A. de Simone, H. Pérez, 2011, Acta crystallographica. Section E, Structure reports online.

Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death.

R. S. Ferreira, A. C. da Silva, V. Pereira, 2017, European journal of medicinal chemistry.

Theoretical and experimental spectroscopic approach of fluorinated Ln(3+)-beta-diketonate complexes.

R. O. Freire, M. O. Rodrigues, F. Paz, 2010, The journal of physical chemistry. A.

2-(4-Methylphenyl)-1H-anthraceno[1,2-d]imidazole-6,11-dione: a fluorescent chemosensor

A. V. Pinto, C. Carvalho, C. A. de Simone, 2009, Acta crystallographica. Section E, Structure reports online.

Selective endocytic trafficking in live cells with fluorescent naphthoxazoles and their boron complexes.

J. R. Corrêa, Gleiston G. Dias, C. Pessoa, 2015, Chemical communications.

A pimpinellin monomer and dimer isolated from the roots of Esenbeckia grandiflora.

P. De Oliveira, C. A. de Simone, L. Conserva, 2004, Acta crystallographica. Section C, Crystal structure communications.

1-(4-Bromophenyl)-2-ethylsulfinyl-2-(phenylselanyl)ethanone monohydrate

E. Tiekink, J. Zukerman-Schpector, C. A. de Simone, 2011, Acta Crystallographica Section E.

3,3-Bis[(4-chlorophenyl)sulfanyl]-1-methylpiperidin-2-one

Carlos A. De Simone, Julio Zukerman-Schpector, Paulo R. Olivato, 2010, Acta crystallographica. Section E, Structure reports online.

Ethyl 2-(3-phenylthioureido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate

J. Ellena, M. D. de Lima, C. A. de Simone, 2012, Acta crystallographica. Section E, Structure reports online.

ent-Trachylobane diterpenoids from Xylopia langsdorffiana.

M. Haun, J. Tavares, E. da‐Cunha, 2006, Journal of natural products.

Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones.

J. Bower, J. Barbosa, K. Salomão, 2017, European journal of medicinal chemistry.

Rhodium(III)-Catalyzed C-H/N-H Alkyne Annulation of Nonsymmetric 2-Aryl (Benz)imidazole Derivatives: Photophysical and Mechanistic Insights.

L. Cury, F. Fantuzzi, A. Sabino, 2020, The Journal of organic chemistry.

Hybrid compounds with two redox centres: modular synthesis of chalcogen-containing lapachones and studies on their antitumor activity.

B. Cavalcanti, A. A. Vieira, A. L. Braga, 2015, European journal of medicinal chemistry.

Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones.

C. K. Andrade, V. Ferreira, R. S. Menna-Barreto, 2008, Bioorganic & medicinal chemistry.

Crystal structure of 4-butyl-6-nitro-2H-1,4-benzothiazin-3-one, C12H14N2O3S

S. Galdino, I. Pitta, C. A. de Simone, 2006 .

Synthesis and structural study of arylidene thiazolidine and benzothiazine compounds

S. Galdino, I. Pitta, M. Perrissin, 2003 .

Crystal structure of (±)-3-[(benzo[d][1,3]dioxol-5-yl)methyl]-2-(3,4,5-trimethoxyphenyl)-1,3-thiazolidin-4-one

J. Ellena, R. Abonía, Juan C Castillo, 2014, Acta crystallographica. Section E, Structure reports online.

2,4,6-Trinitrophenyl 3-chlorobenzoate

J. Ellena, C. A. de Simone, R. Moreno-Fuquen, 2013, Acta crystallographica. Section E, Structure reports online.

4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid: X-ray and DFT-calculated structure.

J. Ellena, C. A. de Simone, R. Moreno-Fuquen, 2011, Acta crystallographica. Section C, Crystal structure communications.

2-(Phenylcarbonothioylsulfanyl)acetic acid

Javier Ellena, Rodolfo Moreno-Fuquen, Carlos Grande, 2010, Acta crystallographica. Section E, Structure reports online.

2-[(2-Carboxyphenyl)disulfanyl]benzoic acid–4,4′-bipyridyl N,N′-dioxide (1/2)

Javier Ellena, Rodolfo Moreno-Fuquen, Carlos A. De Simone, 2010, Acta crystallographica. Section E, Structure reports online.

Computer-Assisted Design of Thiophene-Indole Hybrids as Leishmanial Agents.

E. Muratov, M. Scotti, L. Scotti, 2020, Current topics in medicinal chemistry.

NMR assignments and X‐ray diffraction spectra for two unusual kaurene diterpenes from Erythroxylum barbatum

R. Braz-Filho, E. Silveira, C. A. de Simone, 2005, Magnetic resonance in chemistry : MRC.

2-(2-Nitroanilino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile

Francisco J B Mendonça Junior, Maria do Carmo A de Lima, Suely L Galdino, 2010, Acta crystallographica. Section E, Structure reports online.

2-(2-Nitroanilino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile

Francisco J B Mendonça Junior, Maria do Carmo A de Lima, Suely L Galdino, 2010, Acta crystallographica. Section E, Structure reports online.

trans-5,6-Diphenylperhydropyran-2,4-dione

Carlos A. De Simone, Valéria R. S. Malta, Laura C. de Souza, 2009, Acta crystallographica. Section E, Structure reports online.

3-(2,4-Dibromoanilino)-2,2-dimethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-dione: a new substituted arylamino nor-β-lapachone derivative

C. K. Andrade, R. S. Silva, E. N. da Silva, 2008, Acta crystallographica. Section E, Structure reports online.

Crystal structure of 1,2,5-trimethyl-1,2,3,4-tetrahydropyrido[ 4,3-b]carbazole (guatambuine), C18H20N2, from Aspidosperma subincanum Mart.

C. A. de Simone, V. Malta, M. M. S. Humberto, 2006 .

Crystal structure of diethyl 4-phenyl-2,6-dimethyl- 3,5-pyridinedicarboxylate, C19H21NO4, an multidrug resistance reversal agent from Jatropha elliptica

A. D. da Silva, A. Sant'Ana, C. A. de Simone, 2005 .

Crystal structure of 4-hydroxy-6-propenyl-5,6-dihydro-pyran-2-one, C8H10O3

C. A. de Simone, V. Malta, D. Imbroisi, 2005 .

Crystal structure of (±)-3-[(benzo[d][1,3]dioxol-5-yl)methyl]-2-(3,4,5-trimethoxyphenyl)-1,3-thiazolidin-4-one

J. Ellena, R. Abonía, Juan C Castillo, 2014, Acta crystallographica. Section E, Structure reports online.

Antimony(V) and Bismuth(V) Complexes of Lapachol: Synthesis, Crystal Structure and Cytotoxic Activity

F. Frézard, C. Demicheli, E. Pereira-Maia, 2011, Molecules.

Structural design, synthesis and pharmacological evaluation of 4-thiazolidinones against Trypanosoma cruzi.

R. S. Ferreira, M. Soares, Diogo Rodrigo Magalhaes Moreira, 2015, Bioorganic & medicinal chemistry.

Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.

R. S. Ferreira, A. C. da Silva, V. Pereira, 2014, European journal of medicinal chemistry.

Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones.

J. Bower, J. Barbosa, K. Salomão, 2017, European journal of medicinal chemistry.

cis-Bis[1,1-dibenzyl-3-(furan-2-ylcarbonyl)thioureato-κ2 O,S]copper(II)

J. Ellena, C. A. de Simone, H. Pérez, 2011, Acta crystallographica. Section E, Structure reports online.

1-Hydroxy-3,4-dimethoxy-10-methylacridin-9-one

R. S. D. de Araújo, B. Nyassé, Ernestine N T Zondegoumba, 2020, IUCrData.

Quinone-Derived π-Extended Phenazines as New Fluorogenic Probes for Live-Cell Imaging of Lipid Droplets

M. Vendrell, Gleiston G. Dias, C. A. de Simone, 2018, Front. Chem..

3-arylamino and 3-alkoxy-nor-beta-lapachone derivatives: synthesis and cytotoxicity against cancer cell lines.

C. K. Andrade, B. Cavalcanti, V. Ferreira, 2010, Journal of medicinal chemistry.

Thiazolyl-isatin derivatives: Synthesis, in silico studies, in vitro biological profile against breast cancer cells, mRNA expression, P-gp modulation, and interactions of Akt2 and VIM proteins.

M. Videira, C. A. de Simone, Denise Duarte, 2024, Chemico-biological interactions.