Mikako Yagi

发表

Mitochondrial translation inhibition triggers ATF4 activation, leading to integrated stress response but not to mitochondrial unfolded protein response

T. Uchiumi, D. Kang, Katsuhiko Sasaki, 2020, Bioscience reports.

Cancer genomic profiling identified dihydropyrimidine dehydrogenase deficiency in bladder cancer promotes sensitivity to gemcitabine

Y. Oda, T. Uchiumi, D. Kang, 2022, Scientific Reports.

Doxycycline induces apoptosis via ER stress selectively to cells with a cancer stem cell-like properties: importance of stem cell plasticity

T. Uchiumi, D. Kang, M. Shiota, 2017, Oncogenesis.

Mutation and functional analysis of ABCC2/multidrug resistance protein 2 in a Japanese patient with Dubin–Johnson syndrome

T. Uchiumi, D. Kang, Tomotake Kanki, 2013, Hepatology research : the official journal of the Japan Society of Hepatology.

Cardiomyocyte-specific loss of mitochondrial p32/C1qbp causes cardiomyopathy and activates stress responses

T. Uchiumi, D. Kang, Y. Matsushima, 2017, Cardiovascular research.

Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies

Robert W. Taylor, Alexis A. Jourdain, V. Mootha, 2017, American journal of human genetics.

Mitochondrial translation deficiency impairs NAD+‐mediated lysosomal acidification

T. Uchiumi, D. Kang, Daiki Setoyama, 2021, The EMBO journal.

Mutation of His 834 in human anion exchanger 1 affects substrate binding.

N. Hamasaki, D. Kang, T. Ueda, 2010, Biochimica et biophysica acta.

TFAM expression in brown adipocytes confers obesity resistance by secreting extracellular vesicles that promote self-activation

T. Uchiumi, D. Kang, M. Ikeda, 2022, iScience.

Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis under glucose starvation

T. Uchiumi, D. Kang, K. Yoshimoto, 2022, Oncogenesis.

Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1

Hiroshi Kimura, Mitsuyoshi Nakao, Yasuhiro Ishihara, 2014, Nature Communications.

p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock

T. Uchiumi, Sho Miake, Daiki Setoyama, 2017, EBioMedicine.

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation.

T. Uchiumi, D. Kang, Daiki Setoyama, 2018, Cell reports.

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction

T. Uchiumi, D. Kang, H. Yamaza, 2012, Bioscience reports.

p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability

T. Uchiumi, D. Kang, S. Yoshida, 2012, Nucleic acids research.

Mitochondrial p32/C1QBP is highly expressed in prostate cancer and is associated with shorter prostate‐specific antigen relapse time after radical prostatectomy

K. Kuroiwa, Y. Oda, T. Uchiumi, 2011, Cancer science.

ERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation

T. Uchiumi, D. Kang, Y. Aoki, 2010, Nucleic acids research.

Neural-specific deletion of mitochondrial p32/C1qbp leads to leukoencephalopathy due to undifferentiated oligodendrocyte and axon degeneration

T. Uchiumi, D. Kang, Y. Matsushima, 2017, Scientific Reports.

Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45– TER119–Erythroid and Lymphoid Progenitors

K. Akashi, Y. Kunisaki, T. Uchiumi, 2020, iScience.

Arg 901 in the AE1 C-terminal tail is involved in conformational change but not in substrate binding.

N. Hamasaki, D. Kang, T. Ueda, 2012, Biochimica et biophysica acta.

Serum depletion induced cancer stem cell-like phenotype due to nitric oxide synthesis in oncogenic HRas transformed cells

T. Uchiumi, Takashi Matsumoto, Y. Matsushima, 2016, Oncotarget.

Mitochondrial dysfunction-induced high hCG associated with development of fetal growth restriction and pre-eclampsia with fetal growth restriction

Kiyoko Kato, T. Uchiumi, D. Kang, 2022, Scientific Reports.

Neural-specific deletion of mitochondrial p32/C1qbp leads to leukoencephalopathy due to undifferentiated oligodendrocyte and axon degeneration

T. Uchiumi, D. Kang, Y. Matsushima, 2017, Scientific Reports.

Localization of mRNAs encoding human mitochondrial oxidative phosphorylation proteins.

T. Uchiumi, D. Kang, Tomotake Kanki, 2012, Mitochondrion.

Melanin pigment interrupts the fluorescence staining of mitochondria in melanocytes.

T. Uchiumi, M. Ichihashi, D. Kang, 2016, Journal of dermatological science.

Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA.

T. Uchiumi, D. Kang, Tomotake Kanki, 2012, The Biochemical journal.

The Expression of Ubiquitous Mitochondrial Creatine Kinase Is Downregulated as Prostate Cancer Progression

Y. Oda, T. Uchiumi, D. Kang, 2016, Journal of Cancer.

Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients

T. Uchiumi, D. Kang, H. Yamaza, 2012, Bioscience reports.

Induction of glioblastoma cell ferroptosis using combined treatment with chloramphenicol and 2-deoxy-d-glucose

T. Uchiumi, D. Kang, K. Yoshimoto, 2023, Scientific reports.

FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation.

K. Nakayama, Y. Ohkawa, D. Kang, 2023, Cell reports.

Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA.

T. Uchiumi, D. Kang, Mikako Yagi, 2012, The Biochemical journal.

Improving lysosomal ferroptosis with NMN administration protects against heart failure

D. Kang, Daiki Setoyama, Takahiro Toshima, 2023, Life Science Alliance.

Mutation of His 834 in human anion exchanger 1 affects substrate binding.

N. Hamasaki, D. Kang, T. Ueda, 2010, Biochimica et biophysica acta.

Cardiomyocyte-specific deletion of the mitochondrial transporter Abcb10 causes cardiac dysfunction via lysosomal-mediated ferroptosis

Masatatsu Yamamoto, Daiki Setoyama, Mikako Yagi, 2024, Bioscience reports.