S. Parks

发表

The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)

J. Pouysségur, Sandy Giuliano, H. Endou, 2018, The Journal of Biological Chemistry.

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium

P. Lambin, L. Dubois, A. Harris, 2015, Journal of enzyme inhibition and medicinal chemistry.

Lactate and Acidity in the Cancer Microenvironment

J. Pouysségur, W. Mueller‐Klieser, S. Parks, 2020, Annual Review of Cancer Biology.

Genetic disruption of the pHi-regulating proteins Na+/H+ exchanger 1 (SLC9A1) and carbonic anhydrase 9 severely reduces growth of colon cancer cells

J. Pouysségur, J. Durivault, Yann Cormerais, 2016, Oncotarget.

Circulating tumor cells in prostate cancer: a potential surrogate marker of survival.

Paul Hofman, Emmanuel Chamorey, H. Naman, 2012, Critical reviews in oncology/hematology.

PKC mediates GnRH activation of a Na+/H+ exchanger in goldfish somatotropes.

G. Goss, John P. Chang, S. Parks, 2010, General and comparative endocrinology.

'Warburg effect' controls tumor growth, bacterial, viral infections and immunity - Genetic deconstruction and therapeutic perspectives.

J. Pouysségur, J. Durivault, M. Vucetic, 2022, Seminars in cancer biology.

Intracellular pH regulation in isolated trout gill mitochondrion-rich (MR) cell subtypes: evidence for Na+/H+ activity.

G. Goss, M. Tresguerres, F. Galvez, 2010, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Theoretical considerations underlying Na(+) uptake mechanisms in freshwater fishes.

G. Goss, M. Tresguerres, S. Parks, 2008, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Blood and gill responses to HCl infusions in the Pacific hagfish (Eptatretus stoutii)

G. Goss, M. Tresguerres, S. Parks, 2007 .

Interactions between Na+ channels and Na+-HCO3- cotransporters in the freshwater fish gill MR cell: a model for transepithelial Na+ uptake.

G. Goss, M. Tresguerres, S. Parks, 2007, American journal of physiology. Cell physiology.

Disrupting proton dynamics and energy metabolism for cancer therapy

J. Pouysségur, J. Chiche, S. Parks, 2013, Nature Reviews Cancer.

Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis

G. Goss, M. Tresguerres, L. Levin, 2009, Proceedings of the National Academy of Sciences.

V-H+ -ATPase translocation during blood alkalosis in dogfish gills: interaction with carbonic anhydrase and involvement in the postfeeding alkaline tide.

C. Wood, G. Goss, M. Tresguerres, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Signal transduction in multifactorial neuroendocrine control of gonadotropin secretion and synthesis in teleosts-studies on the goldfish model.

H. Habibi, C. Grey, G. Goss, 2009, General and comparative endocrinology.

Regulation of ion transport by pH and [HCO3-] in isolated gills of the crab Neohelice (Chasmagnathus) granulata.

G. Goss, M. Tresguerres, C. Luquet, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth.

J. Pouysségur, M. Palacín, Sandy Giuliano, 2016, Cancer research.

Microtubule-dependent relocation of branchial V-H+-ATPase to the basolateral membrane in the Pacific spiny dogfish (Squalus acanthias): a role in base secretion

G. Goss, M. Tresguerres, F. Katoh, 2006, Journal of Experimental Biology.

Genetic ablation of the cystine transporter xCT in PDAC cells inhibits mTORC1, growth, survival and tumor formation via nutrient and oxidative stresses.

J. Pouysségur, J. Durivault, E. Tambutté, 2019, Cancer research.

Disrupting the 'Warburg effect' re-routes cancer cells to OXPHOS offering a vulnerability point via 'ferroptosis'-induced cell death.

J. Pouysségur, M. Vucetic, I. Marchiq, 2017, Advances in biological regulation.

Multimode ionization cell for gas chromatographic detection

J. W. Haas, M. Wise, M. Buchanan, 1986 .

The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code

J. Pouysségur, M. Vucetic, Yann Cormerais, 2017, Front. Oncol..

pH control mechanisms of tumor survival and growth

J. Pouysségur, Jacques Pouyssegur, Johanna Chiche, 2011, Journal of cellular physiology.

Metabolic Plasiticy in Cancers—Distinct Role of Glycolytic Enzymes GPI, LDHs or Membrane Transporters MCTs

J. Pouysségur, I. Marchiq, S. Parks, 2017, Front. Oncol..

MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines

A. Noël, J. Pouysségur, N. Mazure, 2013, Cell Death and Disease.

Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome.

J. Pouysségur, F. Ettore, J. Ferrero, 2014, Biochemical and biophysical research communications.

Targeting pH regulating proteins for cancer therapy-Progress and limitations.

J. Pouysségur, S. Parks, 2017, Seminars in cancer biology.

V-H(+)-ATPase, Na(+)/K(+)-ATPase and NHE2 immunoreactivity in the gill epithelium of the Pacific hagfish (Epatretus stoutii).

G. Goss, M. Tresguerres, S. Parks, 2006, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Cellular mechanisms of Cl- transport in trout gill mitochondrion-rich cells.

G. Goss, M. Tresguerres, S. Parks, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

Chloride Uptake and Base Secretion in Freshwater Fish: A Transepithelial Ion‐Transport Metabolon?

G. Goss, M. Tresguerres, F. Katoh, 2006, Physiological and Biochemical Zoology.

Recovery from blood alkalosis in the Pacific hagfish (Eptatretus stoutii): involvement of gill V-H+-ATPase and Na+/K+-ATPase.

G. Goss, M. Tresguerres, S. Parks, 2007, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Theoretical considerations underlying Na+ uptake mechanisms in freshwater fishes

G. Goss, M. Tresguerres, S. Parks, 2008 .

Serotonin-induced high intracellular pH aids in alkali secretion in the anterior midgut of larval yellow fever mosquito Aedes aegypti L.

H. Onken, D. Moffett, G. Goss, 2009, Journal of Experimental Biology.

Overcoming Therapeutic Challenges for Pancreatic Ductal Adenocarcinoma with xCT Inhibitors.

J. Pouysségur, M. Vucetic, S. Parks, 2021, Advances in experimental medicine and biology.

Hypoxia optimises tumour growth by controlling nutrient import and acidic metabolite export.

J. Pouysségur, I. Marchiq, Yann Cormerais, 2016, Molecular aspects of medicine.

AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity

J. Pouysségur, G. Pagès, J. Durivault, 2018, BMC Cancer.

Hypoxia and cellular metabolism in tumour pathophysiology

J. Pouysségur, Yann Cormerais, S. Parks, 2017, The Journal of physiology.

Amino Acid Transporters Are a Vital Focal Point in the Control of mTORC1 Signaling and Cancer

J. Pouysségur, M. Vucetic, Yann Cormerais, 2020, International journal of molecular sciences.

Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis

S. Marcié, J. Pouysségur, J. Chiche, 2013, Front. Oncol..

The Na+/HCO3− Co‐Transporter SLC4A4 Plays a Role in Growth and Migration of Colon and Breast Cancer Cells

J. Pouysségur, S. Parks, 2015, Journal of cellular physiology.

Hypoxia promotes tumor cell survival in acidic conditions by preserving ATP levels

J. Pouysségur, N. Mazure, L. Counillon, 2013, Journal of cellular physiology.

A Cystine-Cysteine Intercellular Shuttle Prevents Ferroptosis in xCTKO Pancreatic Ductal Adenocarcinoma Cells

J. Pouysségur, J. Durivault, E. Tambutté, 2021, Cancers.