S. Zoffmann

发表

Characterization of Non-peptide Antagonist and Peptide Agonist Binding Sites of the NK1 Receptor with Fluorescent Ligands*

G. Turcatti, J. Lowe, T. Schwartz, 1997, The Journal of Biological Chemistry.

Molecular mechanism of activation and inhibition of 7TM peptide receptors

T. Schwartz, M. Rosenkilde, C. Elling, 1994 .

Identification of the extracellular loop 2 as the point of interaction between the N terminus of the chemokine MIP-1alpha and its CCR1 receptor.

J. Galzi, A. Chollet, S. Zoffmann, 2002, Molecular pharmacology.

Functional monoclonal antibody acts as a biased agonist by inducing internalization of metabotropic glutamate receptor 7

P. Malherbe, B. Bohrmann, H. Matile, 2012, British journal of pharmacology.

Synthesis and characterization of fluorescent and photoactivatable MIP-1alpha ligands and interactions with chemokine receptors CCR1 and CCR5.

G. Turcatti, J. Galzi, A. Chollet, 2001, Journal of medicinal chemistry.

Effect of GLP1R agonists taspoglutide and liraglutide on primary thyroid C-cells from rodent and man.

T. Singer, W. Thasler, T. Pfister, 2013, Journal of molecular endocrinology.

mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis.

Anirvan Ghosh, Tom Dunkley, Sannah Zoffmann, 2016, Cell reports.

Synthesis and Characterization of Fluorescent and Photoactivatable MIP-1 alpha Ligands and Interactions with Chemokine Receptors CCR 1 and CCR 5

G. Turcatti, J. Galzi, S. Zoffmann, 2019 .

Machine learning-powered antibiotics phenotypic drug discovery

Hoa Hue Truong, C. Lerner, Fethallah Benmansour, 2019, Scientific Reports.

The Neurokinin A Receptor Activates Calcium and cAMP Responses through Distinct Conformational States*

S. Edelstein, J. Galzi, B. Bucher, 2001, The Journal of Biological Chemistry.

Conserved HisVI‐17 of the NK‐1 receptor is involved in binding of non‐peptide antagonists but not substance P

T. Schwartz, U. Gether, S. Zoffmann, 1993, FEBS letters.

White-to-brown metabolic conversion of human adipocytes by JAK inhibition

Sannah Zoffmann, Hoa Hue Truong, Michael Prummer, 2014, Nature Cell Biology.

Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor.

T. Schwartz, B. Holst, C. Elling, 1998, Molecular pharmacology.

A random motility assay based on image correlation spectroscopy.

M. Prunotto, M. Prummer, D. Kling, 2012, Biophysical journal.

Topological analysis of the complex formed between neurokinin A and the NK2 tachykinin receptor

D. Bertrand, D. Rognan, J. Galzi, 2007, Journal of neurochemistry.

Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models

Emmanuel Gustin, J. Reumers, P. Peeters, 2023, Chemical research in toxicology.

Machine learning-powered antibiotics phenotypic drug discovery

Fethallah Benmansour, Kenneth Bradley, Andreas Maunz, 2019, Scientific Reports.

A novel antibiotic class targeting the lipopolysaccharide transporter

A. Osterman, F. García-Alcalde, A. Haldimann, 2024, Nature.

Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Mice

A. Augustin, S. Zoffmann, S. Golling, 2024, bioRxiv.