B. M. Seletsky

发表

Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin

Junke Liu, Karen Tendyke, G. Kuznetsov, 2009, Molecular Cancer Therapeutics.

Novel second generation analogs of eribulin. Part III: Blood-brain barrier permeability and in vivo activity in a brain tumor model.

Melvin J. Yu, E. Schuck, Yongbo Hu, 2011, Bioorganic & medicinal chemistry letters.

Novel second generation analogs of eribulin. Part I: Compounds containing a lipophilic C32 side chain overcome P-glycoprotein susceptibility.

Melvin J. Yu, Yongbo Hu, Karen Tendyke, 2011, Bioorganic & medicinal chemistry letters.

Discovery of CC-99677, a Selective Targeted Covalent MAPKAPK2 (MK2) Inhibitor for Autoimmune Disorders.

C. Chuaqui, T. Oravecz, J. McDonald, 2022, Translational research : the journal of laboratory and clinical medicine.

Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions.

Melvin J. Yu, M. Towle, B. Littlefield, 2011, Cancer research.

Case History: Discovery of Eribulin (HALAVEN™), a Halichondrin B Analogue That Prolongs Overall Survival in Patients with Metastatic Breast Cancer

Melvin J. Yu, B. Littlefield, Y. Kishi, 2011 .

Asymmetric Diels-Alder reactions of chiral N-methacryloylsultams with 1,3-dienes

G. Bernardinelli, W. Oppolzer, B. M. Seletsky, 1994 .

Addition of Enantioenriched γ-Oxygenated Allylic Stannanes toN-Acyl Iminium Intermediates: A New Synthesis ofsyn-Amino Alcohol Derivatives

J. A. Marshall, B. M. Seletsky, K. Gill, 2000 .

Synthesis of Protected Carbohydrate Derivatives Through Homologation of Threose and Erythrose Derivatives with Chiral .gamma.-Alkoxy Allylic Stannanes

J. A. Marshall, B. M. Seletsky, G. P. Luke, 1994 .

From micrograms to grams: scale-up synthesis of eribulin mesylate.

Melvin J. Yu, Wanjun Zheng, Boris M Seletsky, 2013, Natural product reports.

Macrocyclic ketone analogues of halichondrin B.

Lynda Tremblay, Melvin J. Yu, Yoshito Kishi, 2004, Bioorganic & medicinal chemistry letters.

Structurally simplified macrolactone analogues of halichondrin B.

Melvin J. Yu, Y. Wang, M. Towle, 2004, Bioorganic & medicinal chemistry letters.

In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B.

Melvin J. Yu, J. J. Chen, D. Quincy, 2001, Cancer research.

Highly syn-Selective Additions of Allylic Stannanes to Protected .alpha.-Amino Aldehydes

J. A. Marshall, B. M. Seletsky, Paul S. Coan, 1994 .

In Vitro and In Vivo Anticancer Activities of Synthetic Macrocyclic Ketone Analogues of Halichondrin B 1

Melvin J. Yu, Y. Wang, D. Quincy, 2001 .

Novel second generation analogs of eribulin. Part II: Orally available and active against resistant tumors in vivo.

Melvin J. Yu, E. Schuck, Yongbo Hu, 2011, Bioorganic & medicinal chemistry letters.