C. M. Astle

发表

Effects of food restriction on aging: separation of food intake and adiposity.

D. Harrison, J. Archer, C. M. Astle, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging

D. Harrison, C. M. Astle, J. Delaittre, 1978, The Journal of experimental medicine.

Glycine supplementation extends lifespan of male and female mice

M. Bogue, D. Vaughan, A. Ryazanov, 2019, Aging cell.

Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice

Cyrus F. Khambatta, J. C. Price, M. Bruss, 2015, Aging cell.

Genetically diverse mice are novel and valuable models of age-associated susceptibility to Mycobacterium tuberculosis

M. Niazi, G. Beamer, D. Harrison, 2014, Immunity & Ageing.

Evaluation of matrix effects in analysis of estrogen using liquid chromatography-tandem mass spectrometry.

N. Guo, K. Schug, D. Harrison, 2011, Journal of separation science.

Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age.

D. Harrison, C. M. Astle, M. Stone, 1989, Journal of immunology.

Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice.

K. Flurkey, C. M. Astle, D. Harrison, 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.

Aging Kit Mutant Mice Develop Cardiomyopathy

A. From, L. Ye, Jianyi(Jay) Zhang, 2012, PloS one.

Effects of dietary restriction on hematopoietic stem-cell aging are genetically regulated.

Jichun Chen, D. Harrison, C. M. Astle, 2008, Blood.

Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction.

Jichun Chen, D. Harrison, C. M. Astle, 2003, Experimental hematology.

Delayed immune aging in diet-restricted B6CBAT6 F1 mice is associated with preservation of naive T cells.

Jichun Chen, D. Harrison, C. M. Astle, 1998, The journals of gerontology. Series A, Biological sciences and medical sciences.

Distinct developmental patterns of short-term and long-term functioning lymphoid and myeloid precursors defined by competitive limiting dilution analysis in vivo.

D. Harrison, R. Zhong, C. M. Astle, 1996, Journal of immunology.

Number and continuous proliferative pattern of transplanted primitive immunohematopoietic stem cells.

D. Harrison, C. Lerner, C. M. Astle, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Cell lines from old immunodeficient donors give normal responses in young recipients.

D. Harrison, C. M. Astle, J. Doubleday, 1977, Journal of immunology.

Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility.

D. Harrison, C. M. Astle, S. Klebanov, 2005, The Journal of endocrinology.

Processing by the thymus is not required for cells that cure and populate W/WV recipients

D. Harrison, C. M. Astle, J. Delaittre, 1979 .

Processing by the thymus is not required for cells that cure and populate W/WV recipients.

D. Harrison, C. M. Astle, J. Delaittre, 1979, Blood.

Long-term repopulating abilities of enriched fetal liver stem cells measured by competitive repopulation.

I. Lemischka, C. Jordan, D. Harrison, 1995, Experimental hematology.

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Marco Pahor, Christy S. Carter, Randy Strong, 2009, Nature.

Fetal Myocardium in the Kidney Capsule: An In Vivo Model of Repopulation of Myocytes by Bone Marrow Cells

L. Ye, Jianyi(Jay) Zhang, Xiaohong Wang, 2012, PloS one.

Hematopoietic precursor cell exhaustion is a cause of proliferative defect in primitive hematopoietic stem cells (PHSC) after chemotherapy.

D. Harrison, R. Gardner, C. M. Astle, 1997, Experimental hematology.

Relative to adult marrow, fetal liver repopulates nearly five times more effectively long-term than short-term.

I. Lemischka, C. Jordan, D. Harrison, 1997, Experimental hematology.

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Z. D. Sharp, S. Pletcher, A. Salmon, 2014, Aging cell.

Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice.

R. de Cabo, D. Sinclair, B. Teter, 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

Ultimate erythropoietic repopulating abilities of fetal, young adult, and old adult cells compared using repeated irradiation

D. Harrison, C. Lerner, C. M. Astle, 1984, The Journal of experimental medicine.

The effect of hypophysectomy on thymic aging in mice.

D. Harrison, J. Archer, C. M. Astle, 1982, Journal of immunology.

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

B. Ames, D. Allison, J. Simpkins, 2013, Aging cell.

Assessing permanent damage to primitive hematopoietic stem cells after chemotherapy using the competitive repopulation assay

D. Harrison, C. Lerner, R. Gardner, 2004, Cancer Chemotherapy and Pharmacology.

Analysis of the stem cell sparing properties of cyclophosphamide

R. Gardner, C. M. Astle, E. McKinnon, 2001, European journal of haematology.

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.

R. de Cabo, D. Sinclair, J. Baur, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Genetic regulation of hematopoietic stem cell exhaustion during development and growth.

Jichun Chen, Rong Yuan, D. Harrison, 2005, Experimental hematology.

Primitive hematopoietic stem cell function in vivo is uniquely high in the CXB-12 mouse strain.

Jichun Chen, D. Harrison, C. M. Astle, 2000, Blood.

Development and aging of primitive hematopoietic stem cells in BALB/cBy mice.

Jichun Chen, D. Harrison, C. M. Astle, 1999, Experimental hematology.

Stem Cell Factor Improves the Repopulating Ability of Primitive Hematopoietic Stem Cells after Sublethal Irradiation (and, to a Lesser Extent) after Bone Marrow Transplantation in Mice

P. Oliver, R. Gardner, C. M. Astle, 1998, Stem cells.

Short- and long-term multilineage repopulating hematopoietic stem cells in late fetal and newborn mice: models for human umbilical cord blood.

D. Harrison, C. M. Astle, D. Harrison, 1997, Blood.

Effects of transplantation on the primitive immunohematopoietic stem cell

D. Harrison, C. M. Astle, M. Stone, 1990, The Journal of experimental medicine.

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

Kenneth L. Hensley, E. Ongini, R. Floyd, 2008, Aging cell.

Genetic regulation of primitive hematopoietic stem cell senescence.

D. Harrison, C. M. Astle, J. Chen, 2000, Experimental hematology.

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer

Dudley Lamming, D. Sabatini, J. de Magalhães, 2016, Aging cell.

Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations.

C. Jordan, D. Harrison, R. Zhong, 1993, Experimental hematology.

Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure

D. Harrison, C. M. Astle, 1982, The Journal of experimental medicine.

Mice severely deficient in growth hormone have normal hematopoiesis.

Y. Sharma, D. Harrison, K. Flurkey, 2005, Experimental hematology.

Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive

Dudley Lamming, D. Sabatini, J. Baur, 2013, Aging cell.

Acarbose improves health and lifespan in aging HET3 mice

T. Slaga, J. Wilkinson, G. Lithgow, 2019, Aging cell.

Genetically diverse mice are novel and valuable models of age-associated susceptibility to Mycobacterium tuberculosis

M. Niazi, G. Beamer, D. Harrison, 2014, Immunity & Ageing.

Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic stem cell function.

Y. Sharma, D. Harrison, C. M. Astle, 2007, Experimental hematology.

POPULATION OF LYMPHOID TISSUES IN CURED W‐ANEMIC MICE BY DONOR CELLS

D. Harrison, C. M. Astle, 1976, Transplantation.

Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice.

S. Novoselov, V. Gladyshev, B. Carlson, 2010, Antioxidants & redox signaling.

Splenic primitive hematopoietic stem cell (PHSC) activity is enhanced by steel factor because of PHSC proliferation.

D. Harrison, C. M. Astle, K. Zsebo, 1994, Blood.

Effects of marrow donor and recipient age on immune responses.

D. Harrison, C. M. Astle, 1984, Journal of immunology.

An aging Interventions Testing Program: study design and interim report

Kenneth L. Hensley, Randy Strong, E. Ongini, 2007, Aging cell.

Hematopoietic stem cell functional failure in interleukin-2-deficient mice.

D. Harrison, C. M. Astle, J. Chen, 2002, Journal of hematotherapy & stem cell research.

Maximum Life Spans in Mice are Extended by Wild Strain Alleles

T. Roderick, Jichun Chen, K. Flurkey, 2001, Experimental biology and medicine.

Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain

Xiangru Xu, G. Wang, H. Gong, 2015, Oncotarget.

The decrease in long-term marrow repopulating capacity seen after transplantation is not the result of irradiation-induced stromal injury.

D. Harrison, R. Gardner, C. M. Astle, 1988, Experimental hematology.

Mitogen Synergism in low-responding CBA/CaJ mice.

D. Harrison, C. M. Astle, 1976, Cellular immunology.

Lymphoid and erythroid repopulation in B6 W-anemic mice: a new unirradiated recipient.

D. Harrison, C. M. Astle, 1991, Experimental hematology.

Characterization of a hematopoietic stem cell with engraftment advantage

Jichun Chen, D. Harrison, C. M. Astle, 2000 .