D. DiRocco

发表

Catalytic asymmetric α-acylation of tertiary amines mediated by a dual catalysis mode: N-heterocyclic carbene and photoredox catalysis.

T. Rovis, D. DiRocco, 2012, Journal of the American Chemical Society.

Development of a Direct Photocatalytic C-H Fluorination for the Preparative Synthesis of Odanacatib.

E. Regalado, Louis-Charles Campeau, R. Britton, 2015, Organic letters.

The Evolution of Chemical High-Throughput Experimentation To Address Challenging Problems in Pharmaceutical Synthesis.

S. Krska, S. Dreher, M. Shevlin, 2017, Accounts of chemical research.

Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods†

Timothy J. Wright, Rebecca T. Ruck, Tyler A. Davis, 2021, Chemical science.

Generic Enhanced Sub/Supercritical Fluid Chromatography: Blueprint for Highly Productive and Sustainable Separation of Primary Hindered Amines

Jimmy O. DaSilva, B. Mann, E. Regalado, 2020 .

Synthesis of Sterically Hindered Primary Amines by Concurrent Tandem Photoredox Catalysis.

T. Rovis, Dan Lehnherr, Yu-hong Lam, 2020, Journal of the American Chemical Society.

The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation

Danielle M. Schultz, E. Sherer, D. MacMillan, 2020, Nature Chemistry.

Direct Arylation of Strong Aliphatic C–H Bonds

Danielle M. Schultz, T. Brewer, D. MacMillan, 2018, Nature.

The discovery of high affinity agonists of GPR109a with reduced serum shift and improved ADME properties.

J. Tata, S. Colletti, J. Imbriglio, 2011, Bioorganic & medicinal chemistry letters.

Oxyfunctionalization of the Remote C-H Bonds of Aliphatic Amines by Decatungstate Photocatalysis.

Danielle M. Schultz, Leo A. Joyce, M. Reibarkh, 2017, Angewandte Chemie.

Mapping the dark space of chemical reactions with extended nanomole synthesis and MALDI-TOF MS

Robert P. Sheridan, Christopher J. Welch, Zhengwei Peng, 2018, Science.

Catalytic asymmetric intermolecular Stetter reactions of enolizable aldehydes with nitrostyrenes: computational study provides insight into the success of the catalyst.

K. Houk, Elizabeth L Noey, T. Rovis, 2012, Angewandte Chemie.

Manufacturing Process Development for Belzutifan, Part 1: A Concise Synthesis of the Indanone Starting Material

Q. Xiang, L. Tan, G. Gong, 2021, Organic Process Research & Development.

Late-stage functionalization of biologically active heterocycles through photoredox catalysis.

Shane W. Krska, P. Váchal, S. Krska, 2014, Angewandte Chemie.

N-heterocyclic carbene and Brønsted acid cooperative catalysis: asymmetric synthesis of trans-γ-lactams.

T. Rovis, D. DiRocco, Xiaodan Zhao, 2011, Journal of the American Chemical Society.

Mechanistic investigation of the enantioselective intramolecular stetter reaction: proton transfer is the first irreversible step.

T. Rovis, Javier Read de Alaniz, A. Silvestri, 2011, Organic letters.

Electrochemical Synthesis of Hindered Primary and Secondary Amines via Proton-Coupled Electron Transfer.

Justin A. Newman, E. Regalado, T. Rovis, 2019, Journal of the American Chemical Society.

Quantum mechanical investigation of the effect of catalyst fluorination in the intermolecular asymmetric Stetter reaction.

Elizabeth L Noey, K. Houk, T. Rovis, 2011, Journal of the American Chemical Society.

Catalytic asymmetric intermolecular stetter reaction of heterocyclic aldehydes with nitroalkenes: backbone fluorination improves selectivity.

T. Rovis, D. Dalton, D. DiRocco, 2009, Journal of the American Chemical Society.

Acridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis.

David A. Nicewicz, François Lévesque, Louis-Charles Campeau, 2016, The Journal of organic chemistry.

Asymmetric N-heterocyclic carbene catalyzed addition of enals to nitroalkenes: controlling stereochemistry via the homoenolate reactivity pathway to access δ-lactams.

T. Rovis, D. DiRocco, Nicholas A. White, 2013, Journal of the American Chemical Society.

Selective Hydrogen Atom Abstraction through Induced Bond Polarization: Direct α-Arylation of Alcohols through Photoredox, HAT, and Nickel Catalysis.

Rebecca T. Ruck, I. Davies, D. MacMillan, 2018, Angewandte Chemie.

Catalytic asymmetric intermolecular Stetter reaction of enals with nitroalkenes: enhancement of catalytic efficiency through bifunctional additives.

T. Rovis, D. DiRocco, 2011, Journal of the American Chemical Society.

Isolable analogues of the Breslow intermediate derived from chiral triazolylidene carbenes.

T. Rovis, D. DiRocco, K. Oberg, 2012, Journal of the American Chemical Society.

Catalytic asymmetric cross-aza-benzoin reactions of aliphatic aldehydes with N-Boc-protected imines.

T. Rovis, D. DiRocco, 2012, Angewandte Chemie.

Photoredox-Catalyzed Hydroxymethylation of Heteroaromatic Bases.

Chelsea A. Huff, S. Krska, R. Cohen, 2016, The Journal of organic chemistry.

A multifunctional catalyst that stereoselectively assembles prodrugs

Yining Ji, Louis-Charles Campeau, Rebecca T. Ruck, 2017, Science.

Aryl amination using ligand-free Ni(II) salts and photoredox catalysis

Ian W. Davies, Spencer D. Dreher, Stephen L. Buchwald, 2016, Science.

Asymmetric Hydrogen Bonding Catalysis for the Synthesis of Dihydroquinazoline-Containing Antiviral, Letermovir.

Katrina W. Lexa, Rebecca T. Ruck, G. Humphrey, 2017, Journal of the American Chemical Society.

Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterization data for all new compounds. See DOI: 10.1039/c5sc03350k

Ian W. Davies, Louis-Charles Campeau, Feng Peng, 2015, Chemical science.

LED‐Illuminated NMR Spectroscopy: A Practical Tool for Mechanistic Studies of Photochemical Reactions

M. Reibarkh, R. Gschwind, C. Thiele, 2019, ChemPhotoChem.

The synthesis and conformational analysis of amino acid-tetrahydroanthranilic acid hybrids

R. Mosley, R. Ball, J. Tata, 2008 .

Facile Quantum Yield Determination via NMR Actinometry.

M. Reibarkh, M. Wismer, Yining Ji, 2018, Organic letters.

Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc04751j

Bing Li, Peter S. Kutchukian, Ian W. Davies, 2016, Chemical science.

Development of a Direct Photocatalytic C—H Fluorination for the Preparative Synthesis of Odanacatib.

E. Regalado, Louis-Charles Campeau, R. Britton, 2016 .

Organocatalytic hydroacylation of unactivated alkenes.

T. Rovis, D. DiRocco, 2011, Angewandte Chemie.

Stereospecific Polymerization of Chiral Oxazolidinone-Functionalized Alkenes

E. Bayram, R. Finke, G. Miyake, 2010 .

I. Davies, I. Mangion, M. McLaughlin, 2015, Chemical science.

Aryl amination using ligand-free Ni(II) salts and photoredox catalysis

I. Davies, D. MacMillan, S. Dreher, 2016, Science.

Acridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis.

David A. Nicewicz, Louis-Charles Campeau, S. Oliver, 2016, The Journal of organic chemistry.

Overcoming Product Inhibition in a Nucleophilic Aromatic Substitution Reaction.

Yining Ji, D. DiRocco, Mikhail Reibarkh, 2024, Organic letters.

Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods

Peter S. Kutchukian, I. Davies, T. Cernak, 2016, Chemical science.

N-heterocyclic carbene and Brønsted acid cooperative catalysis: asymmetric synthesis of trans-γ-lactams.

T. Rovis, D. DiRocco, Xiaodan Zhao, 2011, Journal of the American Chemical Society.

Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 3─Development of a Scalable Enzymatic Oxidation Process

J. McMullen, Yangzhong Qin, D. DiRocco, 2024, Organic Process Research & Development.

Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 6─Development of a Nucleophilic Aromatic Substitution in Water

J. McMullen, D. DiRocco, E. Alwedi, 2024, Organic Process Research & Development.