S. Boyd

发表

Three-Component Azidation of Styrene-Type Double Bonds: Light-Switchable Behavior of a Copper Photoredox Catalyst**

G. Fumagalli, M. Greaney, Pauline T. G. Rabet, 2015, Angewandte Chemie.

Exploiting Photoredox Catalysis for the Synthesis of Tetra- and Di-Hydrofurans

G. Fumagalli, M. Greaney, S. Boyd, 2015 .

Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.

Rhys D O Jones, S. Guichard, W. Shao, 2018, Journal of medicinal chemistry.

Discovery, synthesis and biological evaluation of novel glucokinase activators.

Scott Boyd, G. Currie, B. Hayter, 2005, Bioorganic & medicinal chemistry letters.

Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems.

B. Williamson, Aixiang Xue, S. Boyd, 2022, Molecular pharmaceutics.

Benzylic C-H Azidation Using the Zhdankin Reagent and a Copper Photoredox Catalyst.

G. Fumagalli, M. Greaney, Pauline T. G. Rabet, 2016, Organic letters.

Oxyarylation and aminoarylation of styrenes using photoredox catalysis.

G. Fumagalli, M. Greaney, S. Boyd, 2013, Organic letters.

Virtual Screening in the Cloud Identifies Potent and Selective ROS1 Kinase Inhibitors

J. Sadowski, D. Hargreaves, James S. Scott, 2022, J. Chem. Inf. Model..

Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo Efficacy.

A. Bailey, Robert D. M. Davies, Alastair J. H. Brown, 2017, Journal of medicinal chemistry.

Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3.

J. Debreczeni, A. Turnbull, S. Degorce, 2015, Journal of medicinal chemistry.

Identification of novel inhibitors of urokinase via NMR-based screening.

Jean M. Severin, P. Hajduk, S. Fesik, 2000, Journal of medicinal chemistry.

Discovery of a Thiadiazole-Pyridazine Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.

Mairi M. Littleson, Peter D Smith, Peng-Fei Wang, 2019, Journal of medicinal chemistry.

Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes.

Andrew G. Leach, A. Plowright, Robert D. M. Davies, 2012, Bioorganic & medicinal chemistry letters.

A one step synthesis of 1-alkylpyrazolo[5,4-d]pyrimidines

Scott Boyd, Michael J. Waring, Leonie Campbell, 2008 .

A new and versatile synthesis of 3-substituted oxetan-3-yl methyl alcohols

S. Boyd, Christopher D. Davies, 2014 .

Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRASG12C.

Doyle J Cassar, Nichola L. Davies, J. Breed, 2022, Journal of medicinal chemistry.

Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R).

Scott Boyd, S. Degorce, R. Ducray, 2016, Journal of medicinal chemistry.

An efficient synthesis of 2-alkylpyridines using an alkylation/double decarboxylation strategy

S. Boyd, Craig S. Donald, 2012 .

Design of pyrazolo-pyrimidines as 11β-HSD1 inhibitors through optimisation of molecular electrostatic potential

James S. Scott, G. Robb, J. Swales, 2015 .

Optimization of brain penetrant 11β-hydroxysteroid dehydrogenase type I inhibitors and in vivo testing in diet-induced obese mice.

James S. Scott, A. Turnbull, T. Sjögren, 2014, Journal of medicinal chemistry.

Metal-Free Intermolecular Aminoarylation of Alkynes.

M. Greaney, Pauline T. G. Rabet, S. Boyd, 2017, Angewandte Chemie.

Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration.

Doyle J Cassar, Nichola L. Davies, J. Breed, 2023, Journal of medicinal chemistry.

Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.

E. Hennessy, Nichola L. Davies, A. Doherty, 2021, Journal of Medicinal Chemistry.

Matched triplicate design sets in the optimisation of glucokinase activators – maximising medicinal chemistry information content

Michael J. Waring, David Hargreaves, Nathaniel G. Martin, 2013 .