J. Paquin

发表

Direct C-F bond formation using photoredox catalysis.

M. O. Wolf, G. Sammis, M. Majewski, 2014, Journal of the American Chemical Society.

Monofluorination of Organic Compounds: 10 Years of Innovation.

P. Champagne, J. Paquin, J. Desroches, 2015, Chemical reviews.

Direct allylation of benzyl alcohols, diarylmethanols, and triarylmethanols mediated by XtalFluor-E

Thomas Lebleu, J. Paquin, 2017 .

In situ activation of benzyl alcohols with XtalFluor-E: formation of 1,1-diarylmethanes and 1,1,1-triarylmethanes through Friedel-Crafts benzylation.

P. Champagne, J. Paquin, J. Desroches, 2015, Organic & biomolecular chemistry.

Friedel-Crafts reaction of benzyl fluorides: selective activation of C-F bonds as enabled by hydrogen bonding.

P. Champagne, J. Paquin, J. Desroches, 2014, Angewandte Chemie.

Palladium-catalyzed sequential alkylation–alkenylation reactions: application towards the synthesis of polyfunctionalized fused aromatic rings

M. Lautens, Dino Alberico, J. Paquin, 2005 .

Catalytic asymmetric synthesis with rh-diene complexes: 1,4-addition of arylboronic acids to unsaturated esters.

E. Carreira, C. Stephenson, J. Paquin, 2005, Organic letters.

Synthesis of 2-oxazolines and related N-containing heterocycles using [Et2NSF2]BF4 as a cyclodehydration agent

J. Paquin, L. Angers, Jean-Denys Hamel, 2012 .

Synthesis of N-(2-SF5-ethyl)amines and impact of the SF5 substituent on their basicity and lipophilicity

Paul Langowski, J. Paquin, Audrey Gilbert, 2021, Tetrahedron.

Towards the use of monofluorinated dimyristoylphosphatidylcholines as 19F NMR reporters in bacterial model membranes

M. Auger, M. Gagnon, J. Paquin, 2018 .

Photo-fluorodecarboxylation of 2-aryloxy and 2-aryl carboxylic acids.

G. Sammis, Montserrat Rueda-Becerril, Julian G. West, 2012, Angewandte Chemie.

Synthesis of 5-[(Pentafluorosulfanyl)methyl]-γ-butyrolactones via a Silver-Promoted Intramolecular Cyclization Reaction

J. Paquin, Audrey Gilbert, Majdouline Roudias, 2019, European Journal of Organic Chemistry.

New insights into the influence of monofluorination on dimyristoylphosphatidylcholine membrane properties: A solid-state NMR study.

A. Ulrich, M. Auger, E. Strandberg, 2018, Biochimica et biophysica acta. Biomembranes.

Enantioselective palladium-catalyzed addition of malonates to 3,3-difluoropropenes

M. Drouin, J. Paquin, 2018, Tetrahedron.

Palladium-catalyzed synthesis of monofluoroalkenes from 3,3-difluoropropenes using dimethylmalonate and derivatives as nucleophiles.

S. Tremblay, M. Drouin, J. Paquin, 2017, Organic & biomolecular chemistry.

Highly regioselective gold-catalyzed formal hydration of propargylic gem-difluorides.

J. Paquin, Jean-Denys Hamel, Tatsuru Hayashi, 2017, Organic & biomolecular chemistry.

Complementary Methods for the Introduction of the (E)‐3‐(Pentafluorosulfanyl)allyl Chain unto O‐, N‐, S‐, and C‐Based Nucleophiles

J. Paquin, J. Desroches, Elsa Forcellini, 2016 .

Racemic and enantioselective metal-catalyzed synthesis of SF5-containing diarylmethanols.

J. Paquin, J. Desroches, Ariane Tremblay, 2016, Organic & biomolecular chemistry.

Evaluation of the effect of fluorination on the property of monofluorinated dimyristoylphosphatidylcholines.

M. Auger, M. Gagnon, J. Paquin, 2014, Organic & biomolecular chemistry.

S(N)2' reaction of allylic difluorides with lithium amides and thiolates.

J. Paquin, Maxime Bergeron, David Guyader, 2012, Organic letters.

Synthetic approaches to monofluoroalkenes.

J. Paquin, G. Landelle, Maxime Bergeron, 2011, Chemical Society reviews.

Activation of allylic C-F bonds: palladium-catalyzed allylic amination of 3,3-difluoropropenes.

Heather N. Frost, P. Dubé, Francis Barabé, 2010, Angewandte Chemie.

Characterization of the structure, dynamics and allosteric pathways of human NPP1 in its free form and substrate-bound complex from molecular modeling.

P. Lagüe, P. Mathieu, J. Paquin, 2017, Molecular bioSystems.

Revised mechanistic explanation for the alcohol-promoted amination of benzylic fluorides under highly concentrated conditions: Computational and experimental evidence on a model substrate

Claude Y. Legault, P. Champagne, J. Paquin, 2015 .

Enabling nucleophilic substitution reactions of activated alkyl fluorides through hydrogen bonding.

Claude Y. Legault, S. Beaulieu, P. Champagne, 2013, Organic letters.

Electron donor-acceptor (EDA)-complex enabled SF5Cl addition on alkenes and alkynes

J. Paquin, Audrey Gilbert, Mélodie Birepinte, 2021, Journal of Fluorine Chemistry.

Synthesis of Monofluoroalkenes: A Leap Forward

M. Drouin, J. Paquin, Jean-Denys Hamel, 2018, Synthesis.

Faster initiation in the Friedel-Crafts reaction of benzyl fluorides using trifluoroacetic acid as activator

P. Champagne, J. Paquin, J. Desroches, 2016 .

Organic Fluorine as a Hydrogen-Bond Acceptor: Recent Examples and Applications

P. Champagne, J. Paquin, J. Desroches, 2014, Synthesis.

Triol-promoted activation of C–F bonds: Amination of benzylic fluorides under highly concentrated conditions mediated by 1,1,1-tris(hydroxymethyl)propane

P. Champagne, J. Paquin, M. Drouin, 2013, Beilstein journal of organic chemistry.

Amine–borane complex-initiated SF5Cl radical addition on alkenes and alkynes

Paul Langowski, Mathieu Pucheault, L. Chabaud, 2020, Beilstein journal of organic chemistry.

Thiourea-catalyzed C-F Bond Activation: Amination Reaction of Benzylic Fluorides.

Damien Jardel, B. Bibal, P. Champagne, 2020, Chemistry.

Deoxofluorination Reactions Using N,N-Disubstituted Aminodifluorosulfinium Tetrafluoroborate Salts

A. L’Heureux, Olivier Mahé, J. Paquin, 2013 .

Recent Advances in the Synthesis of Acyl Fluorides

J. Paquin, Marie Gonay, Chloé Batisse, 2020, Synthesis.

Au-catalyzed intramolecular hydroalkoxylation of gem-difluorinated alkynols

J. Paquin, Jean-Denys Hamel, 2018, Journal of Fluorine Chemistry.

Eliminative Deoxofluorination Using XtalFluor-E: A One-Step Synthesis of Monofluoroalkenes from Cyclohexanone Derivatives.

J. Paquin, Mathilde Vandamme, 2017, Organic letters.

Trifluoro(N‐methylmethanaminato)sulfur

P. Champagne, J. Paquin, 2014 .

Activation of C-F bonds α to C-C multiple bonds.

J. Paquin, Jean-Denys Hamel, 2018, Chemical communications.

Fluorine transfer to alkyl radicals.

Pierre Kennepohl, G. Sammis, P. Kennepohl, 2012, Journal of the American Chemical Society.

Exploiting a Difference in Leaving Group Ability: An Approach to β-Substituted Monofluoroalkenes Using gem-Chlorofluoropropenes.

J. Paquin, Jean-Denys Hamel, Mélissa Cloutier, 2016, Organic letters.

Synthesis of Nitriles from Aldoximes and Primary Amides Using XtalFluor-E

J. Paquin, Mathilde Vandamme, Massaba Keita, 2015 .

Recent Advances in Radical Fluorination

G. Sammis, J. Paquin, Claire Chatalova‐Sazepin, 2015, Synthesis.

Synthesis of Monofluoroalkenesvia the Activation of Allylic C-F Bonds: A NovelRoute to β-Aminofluoroalkenes Using Pd-Catalyzed Allylic AminationReactions of 3,3-Difluoropropenes

J. Paquin, 2011 .

The use of fluoride as a leaving group: SN2' displacement of a C-F bond on 3,3-difluoropropenes with organolithium reagents to give direct access to monofluoroalkenes.

J. Paquin, Maxime Bergeron, T. Johnson, 2011, Angewandte Chemie.

Efficient synthesis of silylated 2,2-difluorostyrene derivatives through Suzuki-Miyaura cross-coupling of 2,2-difluoro-1-iodo-1-silylethenes.

J. Paquin, Marc-Olivier Turcotte-Savard, 2013, Organic & biomolecular chemistry.

Synthesis of isocyanides through dehydration of formamides using XtalFluor-E

Olivier Mahé, J. Paquin, Mathilde Vandamme, 2015 .

Synthesis of 1,3,4-oxadiazoles from 1,2-diacylhydrazines using [Et2NSF2]BF4 as a practical cyclodehydration agent.

J. Paquin, L. Angers, Jean-Denys Hamel, 2012, Organic & biomolecular chemistry.

Design, synthesis, and applications of potential substitutes of t-Bu-phosphinooxazoline in Pd-catalyzed asymmetric transformations and their use for the improvement of the enantioselectivity in the Pd-catalyzed allylation reaction of fluorinated allyl enol carbonates.

Marc-André Courtemanche, J. Paquin, Marie-France Pouliot, 2012, The Journal of organic chemistry.

Use of 5,5-(dimethyl)-i-Pr-PHOX as a practical equivalent to t-Bu-PHOX in asymmetric catalysis.

J. Paquin, Marie-France Pouliot, Étienne Bélanger, 2009, Organic letters.

Diastereoselective palladium-catalyzed formate reduction of allylic carbonates as a new entry into propionate units.

M. Lautens, J. Paquin, 2003, Organic letters.

Use of XtalFluor-E as an Alternative to POCl3 in the Vilsmeier-Haack Formylation of C-2-Glycals.

F. Vallée, J. Paquin, J. Martel, 2018, The Journal of organic chemistry.

Evaluation of the compatibility of pentafluorosulfanyl chloride with various solvents and additives

J. Paquin, Audrey Gilbert, 2019, Journal of Fluorine Chemistry.

Allylic Substitution Reactions

M. Lautens, J. Paquin, 2005 .

Direct Esterification of Carboxylic Acids with Perfluorinated Alcohols Mediated by XtalFluor-E.

J. Paquin, Mathilde Vandamme, Audrey Gilbert, 2016, Organic letters.

Diethylaminodifluorosulfinium Tetrafluoroborate (XtalFluor‐E®)

Olivier Mahé, J. Paquin, 2013 .

Amide Formation Using In Situ Activation of Carboxylic Acids with [Et2NSF2]BF4

Olivier Mahé, J. Paquin, J. Desroches, 2013 .

Halogenation of primary alcohols using a tetraethylammonium halide/[Et2NSF2]BF4 combination.

Olivier Mahé, J. Paquin, J. Desroches, 2012, Organic letters.

Hydrogen-Bond-Promoted Friedel–Crafts Reaction of Secondary Propargylic Fluorides: Preparation of 1-Alkyl-1-aryl-2-alkynes

J. Paquin, Jean-Denys Hamel, Mélissa Cloutier, 2017, Synlett.

Asymmetric synthesis of 3,3-diarylpropanals with chiral diene-rhodium catalysts.

E. Carreira, C. Stephenson, J. Paquin, 2005, Journal of the American Chemical Society.

Chiral [2.2.2] dienes as ligands for Rh(I) in conjugate additions of boronic acids to a wide range of acceptors.

E. Carreira, Sonia Serna, J. Paquin, 2004, Organic letters.

Bicyclo[2.2.1]hept‐2‐ene (norbornene)

Dino Alberico, J. Paquin, 2008 .

Palladium-catalyzed sequential alkylation-alkenylation reactions. Application to the synthesis of 2-substituted-4-benzoxepines and 2,5-disubstituted-4-benzoxepines.

M. Lautens, S. Piguel, J. Paquin, 2002, The Journal of organic chemistry.

Palladium-catalyzed sequential alkylation-alkenylation reactions and their application to the synthesis of fused aromatic rings.

M. Lautens, S. Piguel, J. Paquin, 2001, The Journal of organic chemistry.

Unexpected effect of the fluorine atom on the optimal ligand-to-palladium ratio in the enantioselective Pd-catalyzed allylation reaction of fluorinated enol carbonates.

Nicolas Guimond, J. Paquin, Katy Cantin, 2008, Chemical communications.

Enantioselective Pd-catalyzed allylation reaction of fluorinated silyl enol ethers.

M. Tremblay, J. Paquin, Katy Cantin, 2007, Journal of the American Chemical Society.

Diastereoselective palladium-catalyzed formate reduction of allylic carbonates en route to polypropionate systems.

M. Lautens, Anh Chau, J. Paquin, 2006, The Journal of organic chemistry.

Diastereoselective Palladium‐Catalyzed Formate Reduction of Allylic Carbonates as a New Entry into Propionate Units.

M. Lautens, J. Paquin, 2004 .

Catalytic Asymmetric Synthesis with Rh—Diene Complexes: 1,4-Addition of Arylboronic Acids to Unsaturated Esters.

E. Carreira, C. Stephenson, J. Paquin, 2006 .

Regioselective Gold-Catalyzed Hydration of CF3- and SF5-alkynes.

J. Paquin, Majdouline Roudias, Mélissa Cloutier, 2019, Organic letters.

Silver-Promoted Synthesis of 5-[(Pentafluorosulfanyl)methyl]-2-oxazolines.

J. Paquin, Audrey Gilbert, Xavier Bertrand, 2018, Organic letters.

Synthesis of an anion-binding amino acid

C. Barberis, N. Voyer, J. Paquin, 2012 .

Progress in the synthesis of fluorinated phosphatidylcholines for biological applications.

M. Auger, M. Gagnon, J. Paquin, 2018, Organic & biomolecular chemistry.

Recent progress in the racemic and enantioselective synthesis of monofluoroalkene-based dipeptide isosteres

M. Drouin, J. Paquin, 2017, Beilstein journal of organic chemistry.

Synthesis of Acyl Fluorides from Carboxylic Acids Using NaF-Assisted Deoxofluorination with XtalFluor-E.

J. Paquin, Marie Gonay, Chloé Batisse, 2020, The Journal of organic chemistry.

Stereochemical outcomes of C–F activation reactions of benzyl fluoride

D. O'Hagan, P. Champagne, J. Paquin, 2018, Beilstein journal of organic chemistry.

Quinazoline‐4‐piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells

P. Lagüe, J. Sévigny, Marie-Chloé Boulanger, 2015, British journal of pharmacology.

Synthesis of monofluoroalkenes using a Pt-catalyzed amination reaction of cyclic 3,3-difluoropropenes with secondary aliphatic amines

M. Drouin, J. Paquin, Jean-Denys Hamel, 2015 .

Exploiting 3,3-Difluoropropenes for the Synthesis of Monofluoroalkenes

M. Drouin, J. Paquin, Jean-Denys Hamel, 2015, Synlett.

Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy.

Ketul V. Patel, S. Raikar, Princy Khurana, 2021, Bioorganic chemistry.

Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1.

P. Lagüe, Marie-Chloé Boulanger, P. Mathieu, 2018, European journal of medicinal chemistry.

Synthesis of novel substituted pyrimidine derivatives bearing a sulfamide group and their in vitro cancer growth inhibition activity.

R. C.-Gaudreault, P. Lagüe, P. Mathieu, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and growth inhibition activity of fluorinated derivatives of tamoxifen.

R. Gaudreault, J. Lacroix, J. Paquin, 2013, Bioorganic & medicinal chemistry letters.

Stereocontrolled access to unsymmetrical 1,1-diaryl-2-fluoroethenes.

P. Champagne, J. Paquin, G. Landelle, 2009, Organic letters.

Direct C—F Bond Formation Using Photoredox Catalysis.

M. O. Wolf, G. Sammis, M. Majewski, 2014 .

Novel approaches to probe the binding of recoverin to membranes

M. Auger, T. Lefèvre, C. Salesse, 2018, European Biophysics Journal.

Hydrohalogenation of Unactivated Alkenes Using a Methanesulfonic Acid/Halide Salt Combination

L. Chabaud, J. Paquin, Xavier Bertrand, 2021, Synthesis.

Hydrofluorination of Alkenes: A Review.

L. Chabaud, J. Paquin, Xavier Bertrand, 2021, Chemistry, an Asian journal.

Direct Hydrofluorination of Methallyl Alkenes Using a Methanesulfonic Acid/Triethylamine Trihydrofluoride Combination.

J. Paquin, Xavier Bertrand, 2019, Organic letters.

A Flexible Synthetic Approach to Phosphatidylglycerols

M. Auger, M. Gagnon, J. Paquin, 2017 .

Synthesis and properties of monofluorinated dimyristoylphosphatidylcholine derivatives: potential fluorinated probes for the study of membrane topology.

M. Auger, M. Gagnon, V. Turcotte, 2012, Organic & biomolecular chemistry.

Bromination/desilicobromination of silylated monofluoroalkenes using tetrabutylammonium tribromide under microwave conditions

J. Paquin, Bianca Malo-Forest, Jessye-Ann Roy, 2013 .

Monofluoroalkene-isostere as a 19F-NMR label for the peptide backbone: synthesis and evaluation in membrane-bound PGLa and (KIGAKI)3.

S. Grage, A. Ulrich, J. Bürck, 2019, Chemistry.

Introduction of the 4,4,4-trifluorobut-2-ene chain exploiting a regioselective Tsuji-Trost reaction catalyzed by palladium nanoparticles.

J. Paquin, J. Desroches, Rémy Hemelaere, 2015, Organic letters.

Gold N-Heterocyclic Carbene Catalysts for the Hydrofluorination of Alkynes Using Hydrofluoric Acid: Reaction Scope, Mechanistic Studies and the Tracking of Elusive Intermediates.

L. Cavallo, S. Nolan, K. Van Hecke, 2021, Chemistry.

Exploiting the inductive effect of the trifluoromethyl group: regioselective gold-catalyzed hydration of 2,2,2-trifluoroethyl-substituted alkynes.

S. Nolan, Nikolaos V. Tzouras, J. Paquin, 2023, Chemical communications.

Incorporating a Monofluoroalkene into the Backbones of Short Peptides: Evaluating the Impact on Local Hydrophobicity

M. Drouin, J. Paquin, José Laxio Arenas, 2019, Chembiochem : a European journal of chemical biology.

Photoinitiated anti-Hydropentafluorosulfanylation of Terminal Alkynes.

P. Champagne, J. Paquin, Mélodie Birepinte, 2021, Angewandte Chemie.

Light-activation of SF5Cl for the atom transfer radical addition onto alkenes and alkynes

J. Paquin, M. Boucher, Marie-Rose Ouellet-Du Berger, 2023, Journal of Fluorine Chemistry.

Novel approaches to probe the binding of recoverin to membranes

M. Auger, T. Lefèvre, C. Salesse, 2018, European Biophysics Journal.

Influence of the Length and Charge on the Activity of α-Helical Amphipathic Antimicrobial Peptides.

F. Rabanal, A. Ulrich, M. Auger, 2017, Biochemistry.

Stereocontrolled approach to bromofluoroalkenes and their use for the synthesis of tri- and tetrasubstituted fluoroalkenes.

P. Champagne, J. Paquin, X. Barbeau, 2009, Organic letters.

Monofluorination of Organic Compounds: 10 Years of Innovation.

P. Champagne, J. Paquin, J. Desroches, 2015, Chemical reviews.

Evaluation of the effect of fluorination on the property of monofluorinated dimyristoylphosphatidylcholines.

M. Auger, M. Gagnon, J. Paquin, 2014, Organic and biomolecular chemistry.

S(N)2' reaction of allylic difluorides with lithium amides and thiolates.

J. Paquin, Maxime Bergeron, David Guyader, 2012, Organic Letters.

Synthetic approaches to monofluoroalkenes.

J. Paquin, G. Landelle, Maxime Bergeron, 2011, Chemical Society reviews.

Room temperature deoxofluorination of aromatic aldehydes with XtalFluor-E under highly concentrated conditions.

J. Paquin, Olivier Thibeault, Marie Gonay, 2023, Organic & biomolecular chemistry.

Friedel-Crafts reaction of benzyl fluorides: selective activation of C-F bonds as enabled by hydrogen bonding.

P. Champagne, J. Paquin, J. Desroches, 2014, Angewandte Chemie.

Gold-Catalyzed Hydrofluorination of Internal Alkynes Using Aqueous HF.

J. Paquin, Raphaël Gauthier, Marius Mamone, 2019, Organic letters.

Exploiting a Difference in Leaving Group Ability: An Approach to β-Substituted Monofluoroalkenes Using gem-Chlorofluoropropenes.

J. Paquin, Jean-Denys Hamel, Mélissa Cloutier, 2016, Organic letters.

Efficient synthesis of silylated 2,2-difluorostyrene derivatives through Suzuki-Miyaura cross-coupling of 2,2-difluoro-1-iodo-1-silylethenes.

J. Paquin, Marc-Olivier Turcotte-Savard, 2013, Organic & biomolecular chemistry.

The use of fluoride as a leaving group: SN2' displacement of a C-F bond on 3,3-difluoropropenes with organolithium reagents to give direct access to monofluoroalkenes.

J. Paquin, Maxime Bergeron, T. Johnson, 2011, Angewandte Chemie.

Stereoselective synthesis of both stereoisomers of β-fluorostyrene derivatives from a common intermediate.

J. Paquin, L. Angers, G. Landelle, 2011, Organic letters.

Synthesis of Tertiary Fluorides through an Acid-Mediated Deoxyfluorination of Tertiary Alcohols.

L. Chabaud, J. Paquin, Xavier Bertrand, 2023, The Journal of organic chemistry.

Activation of C-F bonds α to C-C multiple bonds.

J. Paquin, Jean-Denys Hamel, 2018, Chemical communications.

Rhodium-Catalyzed Intramolecular Cyclopropanation of Trifluoromethyl- and Pentafluorosulfanyl-Substituted Allylic Cyanodiazoacetates.

A. Charette, J. Paquin, M. Boucher, 2023, Organic letters.

Exploration toward the synthesis of aliphatic SF5-containing compounds using the Kolbe reaction

K. Lam, J. Paquin, Vincent Mastalerz, 2023, Journal of Fluorine Chemistry.

Synthesis and properties of monofluorinated dimyristoylphosphatidylcholine derivatives: potential fluorinated probes for the study of membrane topology.

M. Auger, M. Gagnon, V. Turcotte, 2012, Organic & biomolecular chemistry.

Drastic fluorine effect: complete reversal of the selectivity in the Au-catalyzed hydroalkoxylation reaction of fluorinated haloalkynes.

J. Paquin, Mélissa Cloutier, Marius Mamone, 2020, Chemical communications.