Lu-Gang Yu

发表

Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells

R. Beynon, D. Simpson, J. Rhodes, 2017, The Journal of Biological Chemistry.

Simultaneous determination of serum galectin-3 and -4 levels detects metastases in colorectal cancer patients

J. Rhodes, Lu-Gang Yu, Hannah Barrow, 2012, Cellular Oncology.

Identification of intact peanut lectin in peripheral venous blood

J. Milton, J. Rhodes, B. Campbell, 1998, The Lancet.

Regulation and role of organic anion-transporting polypeptides (OATPs) in drug delivery at the choroid plexus

Lu-Gang Yu, Hao Zhang, Yu-Ning Song, 2010, Journal of Clinical Neuroscience.

Pharmacokinetics, biodistribution and antitumour effects of Sclerotium rolfsii lectin in mice.

A. Ingle, J. Rhodes, S. Inamdar, 2017, Oncology reports.

Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis

J. Rhodes, Xiuli Guo, J. Hilkens, 2010, Molecular Cancer.

Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface.

J. Rhodes, G. Nash, Xiuli Guo, 2009, Cancer research.

Interaction with the heparin-derived binding inhibitors destabilizes galectin-3 protein structure.

L. Lian, J. Turnbull, E. Yates, 2019, Biochemical and biophysical research communications.

Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis

L. Lian, J. Turnbull, E. Yates, 2015, Oncotarget.

The oncofetal Thomsen–Friedenreich carbohydrate antigen in cancer progression

Lu-Gang Yu, 2007, Glycoconjugate Journal.

Circulating galectin-3 in the bloodstream: An emerging promoter of cancer metastasis.

Lu-Gang Yu, 2010, World journal of gastrointestinal oncology.

Exquisite binding specificity of Sclerotium rolfsii lectin toward TF-related O-linked mucin-type glycans

J. Rhodes, S. Inamdar, B. Swamy, 2011, Glycoconjugate Journal.

Regulation and Function of Matrix Metalloproteinase-13 in Cancer Progression and Metastasis

D. Pritchard, Lu-Gang Yu, Shun Li, 2022, Cancers.

Cancer cell resistance to anoikis: MUC1 glycosylation comes to play

Lu-Gang Yu, 2017, Cell Death and Disease.

Appearance of peanut agglutinin in the blood circulation after peanut ingestion promotes endothelial secretion of metastasis-promoting cytokines

C. Chen, J. Rhodes, D. Pritchard, 2021, Carcinogenesis.

Increased Circulation of Galectin-3 in Cancer Induces Secretion of Metastasis-Promoting Cytokines from Blood Vascular Endothelium

C. Chen, J. Rhodes, D. Pritchard, 2013, Clinical Cancer Research.

Serum Galectin-2, -4, and -8 Are Greatly Increased in Colon and Breast Cancer Patients and Promote Cancer Cell Adhesion to Blood Vascular Endothelium

C. Chen, H. Wandall, J. Rhodes, 2011, Clinical Cancer Research.

Ligustrazine derivate DLJ14 reduces multidrug resistance of K562/A02 cells by modulating GSTπ activity.

Yan-na Cheng, B. Zheng, Lu-Gang Yu, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

Roles of galectin-3 in metabolic disorders and tumor cell metabolism.

Lu-Gang Yu, Xiu-Li Guo, Lei Wang, 2019, International journal of biological macromolecules.

Intrinsic tryptophan fluorescence spectroscopy reliably determines galectin-ligand interactions

L. Lian, J. Turnbull, E. Yates, 2019, Scientific Reports.

Inhibition of PTEN expression and activity by angiotensin II induces proliferation and migration of vascular smooth muscle cells

Yan-na Cheng, Yan Wu, Lu-Gang Yu, 2013, Journal of cellular biochemistry.

Glycosylation and Disease

J. Rhodes, B. Campbell, Lu-Gang Yu, 1984, The Lancet.

Serum galectins as potential biomarkers of inflammatory bowel diseases

S. Dodd, S. Subramanian, Lu-Gang Yu, 2020, PloS one.

A Tetramethylpyrazine Piperazine Derivate CXC137 Prevents Cell Injury in SH-SY5Y Cells and Improves Memory Dysfunction of Rats with Vascular Dementia

H. Zhang, Wenfang Wang, Lu-Gang Yu, 2014, Neurochemical Research.

Sclerotium rolfsii Lectin Induces Stronger Inhibition of Proliferation in Human Breast Cancer Cells than Normal Human Mammary Epithelial Cells by Induction of Cell Apoptosis

C. Chen, P. Mahajan, P. Shastry, 2014, PloS one.

The TF-antigen binding lectin from Sclerotium rolfsii inhibits growth of human colon cancer cells by inducing apoptosis in vitro and suppresses tumor growth in vivo.

P. Shastry, J. Rhodes, S. Eligar, 2012, Glycobiology.

Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression.

Lin Zhao, Lu-Gang Yu, Xiu-Li Guo, 2020, Biochemical pharmacology.

Mechanism of tetramethylpyrazine analogue CXC195 inhibition of hydrogen peroxide-induced apoptosis in human endothelial cells.

Xian-Chao Cheng, Yan-na Cheng, Lu-Gang Yu, 2010, Biological & pharmaceutical bulletin.

Metformin incombination with curcumin inhibits the growth, metastasis, and angiogenesis of hepatocellular carcinoma in vitro and in vivo

Zhanqi Cao, Ying Zhang, Yan-na Cheng, 2018, Molecular carcinogenesis.

Galectin-3 Is a Natural Binding Ligand of MCAM (CD146, MUC18) in Melanoma Cells and Their Interaction Promotes Melanoma Progression

M. Morgan, Lu-Gang Yu, E. Maxwell, 2022, Biomolecules.

Peanut agglutinin appearance in the blood circulation after peanut ingestion mimics the action of endogenous galectin-3 to promote metastasis by interaction with cancer-associated MUC1.

J. Rhodes, D. Pritchard, C. Duckworth, 2014, Carcinogenesis.

Sorcin, a potential therapeutic target for reversing multidrug resistance in cancer

P. Zhang, B. Zheng, Lu-Gang Yu, 2012, Journal of Physiology and Biochemistry.

Opposite effects on human colon cancer cell proliferation of two dietary Thomsen‐Friedenreich antigen‐binding lectins

D. Fernig, J. Milton, J. Rhodes, 2001, Journal of cellular physiology.

complicating ulcerative colitis

J. Rhodes, Lu-Gang Yu, A. Dwarakanath, 1995 .

6r, a novel oxadiazole analogue of ethacrynic acid, exhibits antitumor activity both in vitro and in vivo by induction of cell apoptosis and S-phase arrest.

Jinhua Chen, Lu-Gang Yu, Xiu-Li Guo, 2013, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Galectin-3 Interaction with Thomsen-Friedenreich Disaccharide on Cancer-associated MUC1 Causes Increased Cancer Cell Endothelial Adhesion*

J. Hirabayashi, O. Gerasimenko, J. Rhodes, 2007, Journal of Biological Chemistry.

Edible Mushroom (Agaricus bisporus) Lectin, Which Reversibly Inhibits Epithelial Cell Proliferation, Blocks Nuclear Localization Sequence-dependent Nuclear Protein Import*

D. Spiller, M. White, J. Smith, 1999, The Journal of Biological Chemistry.

Lectin-epithelial interactions in the human colon.

J. Rhodes, B. Campbell, Lu-Gang Yu, 2008, Biochemical Society transactions.

Investigation of TF-binding lectins from dietary sources and SRL on proliferation and cell cycle progression in human colon HT29 and SW620 cells

S. Inamdar, B. Swamy, Lu-Gang Yu, 2019, Nutrition and cancer.

An N-terminal Truncated Form of Orp150 Is a Cytoplasmic Ligand for the Anti-proliferative Mushroom Agaricus bisporusLectin and Is Required for Nuclear Localization Sequence-dependent Nuclear Protein Import*

I. Grierson, O. Gerasimenko, O. Petersen, 2002, The Journal of Biological Chemistry.

The anti-inflammatory effects of Morin hydrate in atherosclerosis is associated with autophagy induction through cAMP signaling.

Yan Sun, Yue Zhou, Zhanqi Cao, 2017, Molecular nutrition & food research.

Interaction of galectin-3 with MUC1 on cell surface promotes EGFR dimerization and activation in human epithelial cancer cells

J. Rhodes, J. Hilkens, Lu-Gang Yu, 2017, Cell Death and Differentiation.

The role of galectins in colorectal cancer progression

J. Rhodes, Lu-Gang Yu, Hannah Barrow, 2011, International journal of cancer.

Protein Phosphatase 2A, a Negative Regulator of the ERK Signaling Pathway, Is Activated by Tyrosine Phosphorylation of Putative HLA Class II-associated Protein I (PHAPI)/pp32 in Response to the Antiproliferative Lectin, Jacalin*

J. Rhodes, J. Hamlett, L. Packman, 2004, Journal of Biological Chemistry.

Galectin-3--a jack-of-all-trades in cancer.

Lu-Gang Yu, A. Newlaczyl, 2011, Cancer letters.

Galectins in the Blood Circulation: Potential Therapeutic Targets of Cancer Metastasis

C. Duckworth, Lu-Gang Yu, 2012 .

Suppression of Core 1 Gal-Transferase Is Associated with Reduction of TF and Reciprocal Increase of Tn, sialyl-Tn and Core 3 Glycans in Human Colon Cancer Cells

J. Rhodes, Benjamin Tam, C. Duckworth, 2013, PloS one.

Altered glycosylation in inflammatory bowel disease: A possible role in cancer development

J. Rhodes, B. Campbell, Barry J. Campbell, 2001, Glycoconjugate Journal.

Effect of O-Glycosylation and Sialylation Inhibitors on Classical NLS-Dependent Nuclear Protein Import in HT29-MTX Human Colon Cancer Cells

J. Rhodes, Benjamin Tam, Lu-Gang Yu, 2010 .

Stimulation of proliferation in human colon cancer cells by human monoclonal antibodies against the TF antigen (galactose β1‐3 N‐acetyl‐galactosamine)

D. Fernig, O. Gerasimenko, J. Milton, 1997, International journal of cancer.

Galectin-2 in Health and Diseases

C. Duckworth, Lu-Gang Yu, M. Negedu, 2022, International journal of molecular sciences.

MUC1 O-glycosylation contributes to anoikis resistance in epithelial cancer cells

J. Rhodes, Lu-Gang Yu, T. Piyush, 2017, Cell Death Discovery.

TNF-A decreases the sulphation of mucins and CD44 in human colonic epithelial cells; an effect which may explain the low mucosal sulphation seen in inflammatory bowel disease

J. Rhodes, B. Campbell, Lu-Gang Yu, 2000 .

Expression and Impact of C1GalT1 in Cancer Development and Progression

Lu-Gang Yu, Y. Wan, 2021, Cancers.

The anti-inflammatory effects of Morin hydratein atherosclerosis is associated with autophagyinduction through cAMP signalling

Sun, Yue Zhou, Zhanqi Cao, 2017 .

DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo.

Zhen-Ning Lu, Ying Zhang, Yan-na Cheng, 2017, The international journal of biochemistry & cell biology.

Molecular mechanism of anticancer effect of Sclerotium rolfsii lectin in HT29 cells involves differential expression of genes associated with multiple signaling pathways: A microarray analysis.

S. Inamdar, B. Swamy, Arunkumar Padmanaban, 2015, Glycobiology.

Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells

D. Pritchard, Lu-Gang Yu, Shun Li, 2023, Cell death & disease.

Interaction of the Oncofetal Thomsen–Friedenreich Antigen with Galectins in Cancer Progression and Metastasis

L. Lian, Lu-Gang Yu, P. Sindrewicz, 2016, Front. Oncol..

Sorcin, a potential therapeutic target for reversing multidrug resistance in cancer

P. Zhang, B. Zheng, Lu-Gang Yu, 2012, Journal of Physiology and Biochemistry.

DHPAC, a novel microtubule depolymerizing agent, suppresses angiogenesis and vasculogenic mimicry formation of human non‐small cell lung cancer

Lin Zhao, Lu-Gang Yu, Xiu-Li Guo, 2020, Journal of cellular biochemistry.

Simultaneous determination of serum galectin-3 and -4 levels detects metastases in colorectal cancer patients

J. Rhodes, Lu-Gang Yu, Hannah Barrow, 2013, Cellular Oncology.

A Tetramethylpyrazine Piperazine Derivate CXC137 Prevents Cell Injury in SH-SY5Y Cells and Improves Memory Dysfunction of Rats with Vascular Dementia

H. Zhang, Wenfang Wang, Lu-Gang Yu, 2014, Neurochemical Research.

C1GalT1 expression reciprocally controls tumour cell-cell and tumour-macrophage interactions mediated by galectin-3 and MGL with double impact on cancer development and progression

C. Duckworth, Xindi Shan, Lu-Gang Yu, 2023, Cell death & disease.

Reversible inhibition of proliferation of epithelial cell lines by Agaricus bisporus (edible mushroom) lectin.

J. Smith, D. Fernig, L. Yu, 1993, Cancer research.

Interaction between bacterial peptides, neutrophils and goblet cells: a possible mechanism for neutrophil recruitment and goblet cell depletion in colitis.

L. Yu, J. Milton, J. Rhodes, 2001, Clinical science.