Xinyuan Tong

发表

Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

H. Ji, D. Qu, Lu Lu, 2020, Nature Communications.

Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11

Yi Luan, H. Tian, Yue Liu, 2021, Cancer Research.

Lysyl oxidase inhibition drives the transdifferentiation from lung adenocarcinoma to squamous cell carcinoma in mice

Z. Qin, Xinyuan Tong, Hsinyi Huang, 2018, bioRxiv.

Nanog maintains stemness of Lkb1‐deficient lung adenocarcinoma and prevents gastric differentiation

H. Ji, Lei Xiao, Haiquan Chen, 2021, EMBO molecular medicine.

Oxidative stress-triggered Wnt signaling perturbation characterizes the tipping point of lung adeno-to-squamous transdifferentiation

H. Ji, L. Hui, Zhaoyuan Fang, 2023, Signal Transduction and Targeted Therapy.

KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.

H. Ji, A. Bass, A. Moreira, 2022, Cancer cell.

Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis

Yingyong Hou, H. Ji, Roman K. Thomas, 2021, bioRxiv.

YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression

Yingyong Hou, H. Ji, Fei Li, 2014, Nature Communications.

In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis

H. Ji, Luonan Chen, Kwok-Kin Wong, 2018, Proceedings of the National Academy of Sciences.

LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response.

Zhaoyuan Fang, Hui Wang, Kwok-Kin Wong, 2015, Cancer cell.

YAP promotes malignant progression of Lkb1-deficient lung adenocarcinoma through downstream regulation of survivin.

H. Ji, Wenjing Zhang, Lei Zhang, 2015, Cancer research.

Pathological transition as the arising mechanism for drug resistance in lung cancer

H. Ji, Xinyuan Tong, Yueqing Chen, 2019, Cancer communications.

The mTOR-S6K Pathway Links Growth Signaling to DNA Damage Response by Targeting RNF168

H. Ji, G. Chirn, J. Qin, 2017, Nature Cell Biology.

Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition

Xin Hu, H. Ji, Qingsong Liu, 2019, Nature Communications.

Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition

Xin Hu, H. Ji, Qingsong Liu, 2019, Nature Communications.

Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment

H. Ji, Roman K. Thomas, Kwok-Kin Wong, 2023, National science review.

Efficacy of compound aluminum sulfate injection as a monotherapeutic regimen in non-muscle invasive bladder cancer patients: a retrospective single-arm cohort study

Chunxi Wang, Wen-ying Wang, Yalong Yang, 2021, Translational Andrology and Urology.

The mTOR–S6K pathway links growth signalling to DNA damage response by targeting RNF168

Yong Liu, H. Ji, G. Chirn, 2018, Nature Cell Biology.

Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.

V. Velcheti, Zhaoyuan Fang, Minglei Shi, 2024, Cancer cell.

Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer

V. Velcheti, Fei Li, A. Aguirre, 2023, bioRxiv.

EML4-ALK fusions drive lung adeno-to-squamous transition through JAK-STAT activation

Zhaoyuan Fang, Xiumin Yan, Yongchang Zhang, 2024, The Journal of experimental medicine.