L. Raggatt

发表

Resting and injury‐induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration

D. Hume, S. Millard, Kylie A Alexander, 2017, Immunology and cell biology.

Matrix metalloproteinase-13 influences ERK signalling in articular rabbit chondrocytes.

M. Tiku, N. Partridge, L. Raggatt, 2006, Osteoarthritis and cartilage.

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation

J. Lévesque, I. Winkler, N. Sims, 2012, Leukemia.

Osteomacs support osteoclast-mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model

N. Pavlos, S. Millard, V. Glatt, 2021, bioRxiv.

Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model

N. Pavlos, S. Millard, K. Irvine, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Calcitonin receptor-mediated growth suppression of HEK-293 cells is accompanied by induction of p21WAF1/CIP1 and G2/M arrest.

A. Evdokiou, D. Findlay, G. Atkins, 1999, Molecular endocrinology.

Unraveling macrophage contributions to bone repair.

Kylie A Alexander, A. Wu, A. Pettit, 2013, BoneKEy reports.

HMG- CoA Reductase Inhibitors as Immunomodulators

N. Partridge, L. Raggatt, 2012, Drugs.

Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation.

T. Banović, G. Hill, J. Bromberg, 2009, Blood.

niches and their depletion mobilizes HSCs Bone marrow macrophages maintain hematopoietic stem cell (HSC)

J. Lévesque, I. Winkler, N. Rooijen, 2010 .

HMG-CoA reductase inhibitors as immunomodulators: potential use in transplant rejection.

N. Partridge, L. Raggatt, 2002, Drugs.

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment.

D. Hume, A. Perkins, J. Lévesque, 2018, Blood.

Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches.

D. Hume, J. Lévesque, S. Kaur, 2017, Seminars in cell & developmental biology.

The endosteal bone niche contains macrophages that regulate osteoblast function

D. Hume, Kylie A Alexander, A. Wu, 2007 .

Interleukin-18 Is Regulated by Parathyroid Hormone and Is Required for Its Bone Anabolic Actions*

N. Selvamurugan, E. Shimizu, F. Liew, 2008, Journal of Biological Chemistry.

Parathyroid hormone: a double-edged sword for bone metabolism

L. Qin, N. Partridge, L. Raggatt, 2004, Trends in Endocrinology & Metabolism.

Impairment of the collagenase-3 endocytotic receptor system in cells from patients with osteoarthritis.

K. Hruska, M. Goldring, C. Gatt, 2003, Osteoarthritis and cartilage.

Sustained activation of Erk1/2 MAPK and cell growth suppression by the insert-negative, but not the insert-positive isoform of the human calcitonin receptor.

A. Evdokiou, D. Findlay, L. Raggatt, 2000, The Journal of endocrinology.

Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80(+)VCAM1(+)CD169(+)ER-HR3(+)Ly6G(+) erythroid island macrophages in the mouse.

J. Lévesque, I. Winkler, N. Van Rooijen, 2014, Experimental hematology.

Amphiregulin Is a Novel Growth Factor Involved in Normal Bone Development and in the Cellular Response to Parathyroid Hormone Stimulation*

David C. Lee, J. Tamasi, J. Feyen, 2005, Journal of Biological Chemistry.

Absence of B cells does not compromise intramembranous bone formation during healing in a tibial injury model.

Kylie A Alexander, K. MacDonald, S. Kaur, 2013, The American journal of pathology.

Osteomacs and Bone Regeneration

S. Millard, A. Pettit, L. Raggatt, 2017, Current Osteoporosis Reports.

Cellular and Molecular Mechanisms of Bone Remodeling*

Liza J. Raggatt, Nicola C. Partridge, N. Partridge, 2010, The Journal of Biological Chemistry.

Osteal macrophages: a new twist on coupling during bone dynamics.

D. Hume, A. Pettit, L. Raggatt, 2008, Bone.

Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues.

A. Zannettino, D. Hume, A. Perkins, 2021, Cell Reports.

Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB.

D. Hume, V. Ripoll, A. Cassady, 2008, Gene.

Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

D. Hume, M. Sweet, R. Müller, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification.

Roland Steck, Simranpreet Kaur, M. Wullschleger, 2014, The American journal of pathology.

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

J. Lévesque, I. Winkler, N. Van Rooijen, 2010, Blood.

Fragmentation of macrophages during isolation confounds analysis of single cell preparations from mouse hematopoietic tissues

D. Hume, A. Perkins, J. Lévesque, 2021, bioRxiv.

Explorer Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo

K. Schroder, D. Hume, N. Fazzalari, 2018 .

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

D. Hume, J. Lévesque, S. Millard, 2021, Journal of Hematology & Oncology.

CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair.

D. Hume, M. Wullschleger, J. Lévesque, 2017, Biomaterials.