J. Kao

发表

Quantitation of cytochrome P450 mRNA levels in human skin.

G. Ferron, J. Scatina, S. Ball, 2003, Analytical biochemistry.

Teratogenicity of valproic acid: In vivo and in vitro investigations

S. Fabro, E. Goulding, N. Brown, 1981 .

Species differences in the metabolism of benzoic acid by isolated hepatocytes and kidney tubule fragments.

J. Bridges, J. Fry, J. Kao, 1978, Life sciences.

A reporter gene cellular model for evaluating induction of CYP3A4 by new chemical entities

J. Scatina, L. Yengi, J. Kao, 2006 .

Teratogenicity and lethality of hydantoin derivatives in the mouse: structure--toxicity relationships.

S. Fabro, E. Goulding, N. Brown, 1982, Toxicology and applied pharmacology.

TERATOGENIC POTENTIAL OF VALPROIC ACID

S. Fabro, N. Brown, J. Kao, 1980, The Lancet.

Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane.

F. Azam, A. Shilling, J. Kao, 2006, Journal of pharmacological and toxicological methods.

Using a homology model of cytochrome P450 2D6 to predict substrate site of metabolism

Louis Leung, Raymond J. Unwalla, Christine Humblet, 2010, J. Comput. Aided Mol. Des..

Inductionof O-DeethylaseActivityas an Index to Exposureto Coal-Derived Products and Trace EnvironmentalPollutants

W. D. Bostick, J. Mrochek, J. Kao, 2004 .

Use of laser-excited fluorescence to measure mixed-function oxidase activity.

C. Burtis, B. Egan, N. E. Lee, 1983, Clinical chemistry.

Metabolism of aniline in rats, pigs and sheep.

J. Bridges, J. Kao, J. Faulkner, 1978, Drug metabolism and disposition: the biological fate of chemicals.

Induction of the hepatic cytochrome P-450-dependent mono-oxygenase system in young and geriatric rats.

J. Kao, P. Hudson, 1980, Biochemical pharmacology.

Effect of ellagic and caffeic acids on covalent binding of benzo[a]pyrene to epidermal DNA of mouse skin in organ culture.

L. Shugart, J. Kao, 1984, The International journal of biochemistry.

A comparison of drug-metabolizing capability in isolated viable rat hepatocytes and renal tubule fragments.

J. Bridges, J. Fry, J. Kao, 1978, Xenobiotica; the fate of foreign compounds in biological systems.

A comparison of xenobiotic metabolism in cells isolated from rat liver and small intestinal mucosa.

J. Bridges, J. Fry, J. Kao, 1979, Biochemical pharmacology.

Venlafaxine (VF): Effects on CYP2D6 dependent imipramine (IMP) and desipramine (DMP) 2‐hydroxylation; Comparative studies with fluoxetine (FLU) and effects on CYP1A2, CYP3A4 and CYP2C9

J. Scatina, S. Ball, J. Kao, 1996 .

In vitro percutaneous absorption in mouse skin: influence of skin appendages.

J. Hall, J. Kao, G. Helman, 1988, Toxicology and applied pharmacology.

Metabolism of [14C]phenol by sheep, pig and rat.

J. K. Faulkner, J. Bridges, J. Kao, 1979, Xenobiotica; the fate of foreign compounds in biological systems.

The Conduct of In Vitro and In Vivo Drug‐Drug Interaction Studies: A PhRMA Perspective

Amy Roe, Volker Fischer, John Kao, 2003, Journal of clinical pharmacology.

The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective.

Amy Roe, R Scott Obach, Volker Fischer, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Inhibition of zaleplon metabolism by cimetidine in the human liver: in vitro studies with subcellular fractions and precision-cut liver slices

D. G. Walters, J. Tredger, R. J. Price, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

The Evolving Role of Drug Metabolism in Drug Discovery and Development

Louis Leung, L. Yengi, J. Kao, 2007, Pharmaceutical Research.

Development of a UGT1A1 reporter gene assay for induction studies: correlation between reporter gene data and regulation of UGT1A1 in human hepatocytes.

J. Scatina, L. Yengi, J. Kao, 2010, Drug metabolism letters.

A multisample apparatus for kinetic evaluation of skin penetration in vitro: the influence of viability and metabolic status of the skin.

J. M. Holland, J. Kao, M. Whitaker, 1984, Toxicology and applied pharmacology.

Population distribution and effects on drug metabolism of a genetic variant in the 5′ promotor region of CYP3A4

P. Hopkins, G. Ferron, J. Scatina, 1999, Clinical pharmacology and therapeutics.

Skin absorption and cutaneous first pass metabolism of topical steroids: in vitro studies with mouse skin in organ culture.

J. Hall, J. Kao, 1987, The Journal of pharmacology and experimental therapeutics.

Skin penetration and metabolism of topically applied chemicals in six mammalian species, including man: an in vitro study with benzo[a]pyrene and testosterone.

J Kao, F K Patterson, J Hall, 1985, Toxicology and applied pharmacology.

Use of a quantitative real-time reverse transcription-polymerase chain reaction method to study the induction of CYP1A, CYP2B and CYP4A forms in precision-cut rat liver slices

R. J. Price, A. Renwick, B. Lake, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

An in vitro approach to studying cutaneous metabolism and disposition of topically applied xenobiotics.

L. Shugart, J. M. Holland, J. Hall, 1984, Toxicology and applied pharmacology.

[14C]7-ethoxycoumarin metabolism by precision-cut rat hepatic slices.

J. Scatina, S. Sisenwine, S. Ball, 1996, Drug metabolism and disposition: the biological fate of chemicals.

Metabolism of Zaleplon by human hepatic microsomal cytochrome P450 isoforms.

D. G. Walters, A. Renwick, B. Lake, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Correlating Efficacy in Rodent Cognition Models with In Vivo 5-HT 1 A Receptor Occupancy by a Novel Antagonist

Hughes, M. Day, T. Comery, 2008 .

Correlating Efficacy in Rodent Cognition Models with in Vivo 5-Hydroxytryptamine1A Receptor Occupancy by a Novel Antagonist, (R)-N-(2-Methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane Carboxamide (WAY-101405)

M. Day, T. Comery, S. Grauer, 2008, Journal of Pharmacology and Experimental Therapeutics.

An in vitro approach to studying cutaneous metabolism and disposition of topically applied xenobiotics

L. Shugart, J. M. Holland, J. Kao, 1983 .

Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase

R. J. Price, A. Renwick, B. Lake, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Examination of adduct formation in vivo in the mouse between benzo(a)pyrene and DNA of skin and hemoglobin of red blood cells.

L. Shugart, J. Kao, 1985, Environmental health perspectives.

Lipopolysaccharide-mediated modulation of cytochromes P450 in Stat1 null mice.

Jun-yan Hong, J. Scatina, S. Ball, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Acute dermal toxicity: in vivo and in vitro comparisons in mice.

J. Hall, R. Helman, J. Kao, 1986, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Quantitation of cutaneous toxicity: an in vitro approach using skin organ culture.

J. M. Holland, J. Hall, J. Kao, 1983, Toxicology and applied pharmacology.

Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications.

K. Marquis, J. Dunlop, Louis Leung, 2006, CNS drug reviews.

Desvenlafaxine and venlafaxine exert minimal in vitro inhibition of human cytochrome P450 and P-glycoprotein activities.

F. Azam, Louis Leung, A. Shilling, 2009, Psychopharmacology bulletin.

Induction of CYP3A isoforms in cultured precision-cut human liver slices.

J. Tredger, R. J. Price, A. Renwick, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

In vivo and in vitro metabolism of foreign chemicals in various animal species

J. Kao, 1977 .

Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.

J. Scatina, S E Ball, S. Ball, 1997, British journal of clinical pharmacology.