T. Ohtsuka

发表

Panclicins, novel pancreatic lipase inhibitors. II. Structural elucidation.

K. Yoshinari, M. Aoki, T. Ohtsuka, 1994, The Journal of antibiotics.

A new series of natural antifungals that inhibit P450 lanosterol C-14 demethylase. I. Taxonomy, fermentation, isolation and structural elucidation.

H. Kotaki, N. Shimma, T. Ohtsuka, 1992, The Journal of antibiotics.

Non-peptidic inhibitors of human chymase. Synthesis, structure-activity relationships, and pharmacokinetic profiles of a series of 5-amino-6-oxo-1,6-dihydropyrimidine-containing trifluoromethyl ketones.

M. Nakajima, T. Imada, M. Miyazaki, 2001, Bioorganic & medicinal chemistry.

Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489. II. Isolation, characterization and biological activities.

H. Kotaki, M. Arisawa, H. Seto, 1993, The Journal of antibiotics.

Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp.

H. Kotaki, H. Seto, N. Shimma, 1992, The Journal of antibiotics.

Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase.

K. Kawasaki, S. Sogabe, K. Morikami, 2003, Bioorganic & medicinal chemistry.

Cyclothiazomycin, a novel polythiazole-containing peptide with renin inhibitory activity. Taxonomy, fermentation, isolation and physico-chemical characterization.

H. Seto, H. Yasuno, M. Aoki, 1991, The Journal of antibiotics.

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 3.

S. Niizuma, K. Kawasaki, S. Sogabe, 2003, Bioorganic & medicinal chemistry letters.

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 1.

K. Kawasaki, S. Sogabe, N. Shimma, 2001, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors.

M. Sakaitani, T. Fukami, N. Shimma, 2009, Bioorganic & medicinal chemistry letters.

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 3.

S. Niizuma, K. Kawasaki, S. Sogabe, 2003, Bioorganic & medicinal chemistry letters.

Structure of cyclothiazomycin, a unique polythiazole-containing peptide with renin inhibitory activity. Part 1. Chemistry and partial structures of cyclothiazomycin

H. Seto, K. Furihata, M. Aoki, 1991 .

Structure of cyclothiazomycin, a unique polythiazole-containing peptide with renin inhibitory activity. Part 2. Total structure

H. Seto, K. Furihata, M. Aoki, 1991 .

Hispidospermidin, a novel phospholipase C inhibitor produced by Chaetosphaeronema hispidulum (Cda) Moesz NR 7127. II. Isolation, characterization and structural elucidation.

H. Seto, N. Shimma, T. Ohtsuka, 1994, The Journal of antibiotics.

Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489. III. Structural elucidation.

H. Seto, N. Shimma, T. Ohtsuka, 1993, The Journal of antibiotics.

Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489. I. Taxonomy, yield improvement and fermentation.

Y. Anzai, T. Okuda, T. Ohtsuka, 1993, The Journal of antibiotics.

Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic alpha-keto heterocycles as novel inhibitors of human chymase.

M. Nakajima, H. Sakashita, T. Imada, 2001, Journal of medicinal chemistry.

Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic difluoromethylene ketones as novel inhibitors of human chymase.

M. Miyazaki, M. Eda, M. Nakajima, 2001, Journal of medicinal chemistry.

3D-QSAR study of antifungal N-myristoyltransferase inhibitors by comparative molecular surface analysis

Nobuo Shimma, Yasuhiko Shiratori, Tatsuo Ohtsuka, 2003 .

Crystal structures of Candida albicans N-myristoyltransferase with two distinct inhibitors.

F. Winkler, D. Banner, A. D'arcy, 2002, Chemistry & biology.

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2.

K. Kawasaki, S. Sogabe, K. Morikami, 2002, Bioorganic & medicinal chemistry letters.

Cassette Dosing Approach and Quantitative Structure-Pharmacokinetic Relationship Study of Antifungal N-Myristoyltransferase Inhibitors

Kiyoshi Hasegawa, Yuko Aoki, Nobuo Shimma, 2002, J. Chem. Inf. Comput. Sci..

N-Myristoyltransferase inhibitors as potential antifungal drugs

Y. Aoki, T. Ohtsuka, 2003 .

Hispidospermidin, a Novel Phospholipase C Inhibitor Produced by Chaetosphaeronema hispidulum (Cda) Moesz NR 7127. Part 2. Isolation, Characterization and Structural Elucidation.

H. Seto, N. Shimma, T. Ohtsuka, 1994 .

The Reaction of b-Aminoenones with N-Substituted Ureas

Y. Tsuda, Yasuhiro Yamamoto, T. Ohtsuka, 1976 .

Cyclothialidine, a novel DNA gyrase inhibitor. II. Isolation, characterization and structure elucidation.

N. Shimma, T. Kamiyama, T. Ohtsuka, 1994, The Journal of antibiotics.