V. Novokhatny

发表

Safety evaluation of a recombinant plasmin derivative lacking kringles 2–5 and rt-PA in a rat model of transient ischemic stroke

J. LaManna, V. Marder, V. Arora, 2012, Experimental & Translational Stroke Medicine.

Distinct dose-dependent effects of plasmin and TPA on coagulation and hemorrhage.

V. Marder, G. Jesmok, D. Stewart, 2003, Blood.

Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential

V. Marder, V. Novokhatny, 2010, Journal of thrombosis and haemostasis : JTH.

Fluorescence spectroscopic analysis of ligand binding to kringle 1 + 2 + 3 and kringle 1 fragments from human plasminogen.

Y. Matsuka, V. Novokhatny, S. Kudinov, 1990, European journal of biochemistry.

Analysis of ligand binding to kringles 4 and 5 fragments from human plasminogen.

V. Novokhatny, S. Kudinov, Matsuka YuV, 1989, Thrombosis research.

Comparison of local thrombolytic efficacy of plasmin and rt-PA in an in-vitro flow system; a pilot study

V. Marder, F. Bajd, I. Serša, 2013, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Thrombolytic potency of acid‐stabilized plasmin: superiority over tissue‐type plasminogen activator in an in vitro model of catheter‐assisted thrombolysis

V. Novokhatny, T. Zimmerman, K. Taylor, 2003, Journal of thrombosis and haemostasis : JTH.

Locally delivered plasmin: why should it be superior to plasminogen activators for direct thrombolysis?

V. Marder, G. Jesmok, V. Novokhatny, 2004, Trends in pharmacological sciences.

Fragment K 2-3 of plasminogen molecule carries a lysine-binding site

Y. Matsuka, V. Novokhatny, S. Kudinov, 1986 .

Domain structure and interactions of recombinant urokinase-type plasminogen activator.

A. Mazar, J. Henkin, P. Marcotte, 1992, The Journal of biological chemistry.

Haemostatic safety of a unique recombinant plasmin molecule lacking kringles 2–5

V. Marder, P. Scuderi, S. Petteway, 2010, Thrombosis and Haemostasis.

Simplified recombinant plasmin: Production and functional comparison of a novel thrombolytic molecule with plasma-derived plasmin

P. Scuderi, S. Petteway, V. Novokhatny, 2008, Thrombosis and Haemostasis.

Characterization of plasminogen as an adhesive ligand for integrins αMβ2 (Mac-1) and α5β1 (VLA-5)

T. Ugarova, Tatiana P. Ugarova, V. Yakubenko, 2004 .

Characterization of plasminogen as an adhesive ligand for integrins alphaMbeta2 (Mac-1) and alpha5beta1 (VLA-5).

T. Ugarova, V. Yakubenko, Helen V. Skomorovska-Prokvolit, 2004, Blood.

Domains in human plasminogen.

P. Privalov, V. Novokhatny, S. Kudinov, 1984, Journal of molecular biology.

Influence of carbohydrate on structure, stability, and function of gelatin-binding fragments of fibronectin.

S. Brew, K. Ingham, V. Novokhatny, 1995, Archives of biochemistry and biophysics.

Structure and activity of plasmin and other direct thrombolytic agents.

V. Novokhatny, 2008, Thrombosis research.

Tissue-type Plasminogen Activator (tPA) Interacts with Urokinase-type Plasminogen Activator (uPA) via tPA's Lysine Binding Site

H. Lijnen, L. Medved, K. Ingham, 1995, The Journal of Biological Chemistry.

Domain structure and domain-domain interactions of recombinant tissue plasminogen activator.

L. Medved, K. Ingham, V. Novokhatny, 1991, The Journal of biological chemistry.

Direct microscopic monitoring of initial and dynamic clot lysis using plasmin or rt-PA in an in vitro flow system.

V. Marder, F. Bajd, I. Serša, 2014, Thrombosis research.

Thermodynamics of maltose binding protein unfolding

K. Ingham, V Novokhatny, K Ingham, 1997, Protein science : a publication of the Protein Society.

Domain structure and domain-domain interactions in the carboxy-terminal heparin binding region of fibronectin.

D. Atha, F. Schwarz, K. Ingham, 1992, Journal of molecular biology.

Reversible unfolding of an isolated heparin and DNA binding fragment, the first type III module from fibronectin.

S. Brew, K. Ingham, S. Litvinovich, 1992, Biochimica et biophysica acta.

Characterization of plasminogen as an adhesive ligand for integrins (cid:1) M (cid:2) 2 (Mac-1) and (cid:1) 5 (cid:2) 1 (VLA-5)

T. Ugarova, V. Yakubenko, Helen V. Skomorovska-Prokvolit, 2004 .

Acid‐Stabilized Plasmin as a Novel Direct‐Acting Thrombolytic

P. Scuderi, S. Petteway, V. Novokhatny, 2012 .

Domain structure of the Fib-1 and Fib-2 regions of human fibronectin. Thermodynamic properties of the type I finger module.

K. Ingham, V. Novokhatny, 1994, Journal of Molecular Biology.

Blood inhibitory capacity toward exogenous plasmin

V. Novokhatny, T. Zimmerman, A. Bańbuła, 2007, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Haemostatic safety of a unique recombinant plasmin molecule lacking kringles 2–5

V. Marder, P. Scuderi, S. Petteway, 2010, Thrombosis and Haemostasis.

Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential

V. Novokhatny, V. J. Marder, 2010, Journal of thrombosis and haemostasis : JTH.