K. Takada

发表

Intravenous and oral administrations of DD2 [7-Amino-2-(sulfanylmethyl)heptanoic acid] produce thrombolysis through inhibition of plasma TAFIa in rats with tissue factor-induced microthrombosis.

H. Yamazaki, K. Sugimoto, Keiko Yamamoto, 2012, Thrombosis research.

Peroxisome proliferator-activated receptor-alpha agonists repress expression of thrombin-activatable fibrinolysis inhibitor by decreasing transcript stability

K. Sugimoto, Tomoyuki Sasaki, Y. Masuda, 2012, Thrombosis and Haemostasis.

Bleomycin induces E-selectin expression in cultured umbilical vein endothelial cells by increasing its mRNA levels through activation of NF-kappaB/Rel.

H. Ishii, K. Takada, 2002, Toxicology and applied pharmacology.

Verotoxin-1 stimulation of macrophage-like THP-1 cells up-regulates tissue factor expression through activation of c-Yes tyrosine kinase: Possible signal transduction in tissue factor up-regulation.

S. Horie, K. Oida, T. Higuchi, 2006, Biochimica et biophysica acta.

Verotoxin-1 Induces Tissue Factor Expression in Human Umbilical Vein Endothelial Cells through Activation of NF-κB/Rel and AP-1

T. Higuchi, H. Ishii, J. Sugiyama, 2000, Thrombosis and Haemostasis.

Oxidized phospholipids in oxidized low-density lipoprotein down-regulate thrombomodulin transcription in vascular endothelial cells through a decrease in the binding of RARbeta-RXRalpha heterodimers and Sp1 and Sp3 to their binding sequences in the TM promoter.

S. Horie, K. Oida, H. Ishikawa, 2003, Blood.

and 3 to their binding sequences in the TM promoter heterodimers and Sp 1 α-RXR β through a decrease in the binding of RAR cellsdownregulate thrombomodulin transcription in vascular endothelial Oxidized phospholipids in oxidized low-density lipoprotein

S. Horie, K. Oida, H. Ishikawa, 2003 .

Sp 1 and Sp 3 to their binding sequences in the TM promoter heterodimers and α-RXR β cells through a decrease in the binding of RAR downregulate thrombomodulin transcription in vascular endothelial Oxidized phospholipids in oxidized low-density lipoprotein

S. Horie, K. Oida, H. Ishikawa, 2003 .

Endothelin-1 secretion from cultured vascular endothelial cells of DOCA-salt hypertensive rats.

M. Takaoka, Y. Matsumura, K. Takada, 1996, Life sciences.

Sp1 is an essential transcription factor for LPS-induced tissue factor expression in THP-1 monocytic cells, and nobiletin represses the expression through inhibition of NF-kappaB, AP-1, and Sp1 activation.

T. Higuchi, Y. Masuda, H. Ishii, 2008, Biochemical pharmacology.

Capillin, a major constituent of Artemisia capillaris Thunb. flower essential oil, induces apoptosis through the mitochondrial pathway in human leukemia HL-60 cells.

Y. Masuda, K. Takada, J. Kitajima, 2015, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Nobiletin represses change in the levels of blood coagulation markers in the LPS-induced rat DIC model

Y. Masuda, K. Takada, A. Ito, 2020 .

Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells

Y. Masuda, K. Takada, J. Kitajima, 2015, Journal of Natural Medicines.

PI3-Kinase Inhibitor LY294002 Repressed the Expression of Thrombin-Activatable Fibrinolysis Inhibitor in Human Hepatoma HepG2 Cells.

Y. Masuda, K. Takada, J. Yazawa, 2015, Biological & pharmaceutical bulletin.

PI 3-Kinase Inhibitor LY 294002 Repressed the Expression of Thrombin-Activatable Fibrinolysis Inhibitor in Human Hepatoma HepG 2 Cells

Y. Masuda, K. Takada, J. Yazawa, 2015 .

Nobiletin, a polymethoxyflavone in citrus fruits, reduces TAFI expression in HepG2 cells through transcriptional inhibition

Tomoyuki Sasaki, Y. Masuda, H. Ishii, 2013, Thrombosis and Haemostasis.

Expression of thrombin-activatable fibrinolysis inhibitor (TAFI) is up-regulated by increase in intracellular cyclic AMP levels in cultured HepG2 cells

K. Sugimoto, Y. Masuda, H. Ishii, 2009, Thrombosis and Haemostasis.

Angiotensin II binding activity in cultured porcine arterial endothelial cells.

C. Mineo, T. Takano, T. Imanaka, 1994, Biochemical pharmacology.

Ursolic acid and oleanolic acid, members of pentacyclic triterpenoid acids, suppress TNF-α-induced E-selectin expression by cultured umbilical vein endothelial cells.

K. Masuda, H. Ishii, T. Nakane, 2010, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Simultaneous inhibition of Chk1 and Bcl-xL induces apoptosis in vitro and represses tumour growth in an in vivo xenograft model

O. Takeuchi, Y. Masuda, Masayoshi Hirohara, 2022, Journal of chemotherapy.

Bcl-2/Bcl-xL inhibitor navitoclax increases the antitumor effect of Chk1 inhibitor prexasertib by inducing apoptosis in pancreatic cancer cells via inhibition of Bcl-xL but not Bcl-2

O. Takeuchi, Y. Masuda, Masayoshi Hirohara, 2020, Molecular and Cellular Biochemistry.

Prexasertib increases the sensitivity of pancreatic cancer cells to gemcitabine and S‑1

O. Takeuchi, Y. Masuda, Masayoshi Hirohara, 2020 .