M. Darsley

发表

Isoabzymes: structurally and mechanistically similar catalytic antibodies from the same immunization.

P. Schultz, J. Kenten, R. Sanchez, 1993, Biochemistry.

Aspects of antibody-catalyzed primary amide hydrolysis

G. Blackburn, R. Titmas, G. Blackburn, 1994, Applied biochemistry and biotechnology.

Genetically modified enterotoxigenic Escherichia coli vaccines induce mucosal immune responses without inflammation

N. Thomas, N. Croft, I. Sanderson, 2007, Gut.

An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli

D. Sack, S. Chakraborty, D. Tribble, 2016, PloS one.

Safety and immunogenicity of a prototype recombinant alpha-like protein subunit vaccine (GBS-NN) against Group B Streptococcus in a randomised placebo-controlled double-blind phase 1 trial in healthy adult women.

A. Pawłowski, B. Johansson‐Lindbom, D. Bell, 2021, Vaccine.

A group B Streptococcus alpha-like protein subunit vaccine induces functionally active antibodies in humans targeting homotypic and heterotypic strains

A. Pawłowski, M. Hedegaard, B. Johansson‐Lindbom, 2022, Cell reports. Medicine.

New family of exon-shuffled recombinant genes reveals extensive interdomain interactions in class I histocompatibility antigens and identifies residues involved

E. Appella, J. Frelinger, K. Ozato, 1987, The Journal of experimental medicine.

CYTOTOXIC T LYMPHOCYTE RECOGNITION OF HYBRID MHC CLASS I MOLECULES

E. Appella, J. Frelinger, M. Macchi, 1988, Journal of immunogenetics.

The Oral, Live Attenuated Enterotoxigenic Escherichia coli Vaccine ACE527 Reduces the Incidence and Severity of Diarrhea in a Human Challenge Model of Diarrheal Disease

D. Sack, S. Chakraborty, A. L. Bourgeois, 2012, Clinical and Vaccine Immunology.

A Combination Vaccine Consisting of Three Live Attenuated Enterotoxigenic Escherichia coli Strains Expressing a Range of Colonization Factors and Heat-Labile Toxin Subunit B Is Well Tolerated and Immunogenic in a Placebo-Controlled Double-Blind Phase I Trial in Healthy Adults

D. Sack, S. Chakraborty, H. Bloomberg, 2011, Clinical and Vaccine Immunology.

Campylobacter jejuni strain CG8421: a refined model for the study of Campylobacteriosis and evaluation of Campylobacter vaccines in human subjects.

K. Pierce, C. Huston, D. Tribble, 2009, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Caught in the Act: In Vivo Development of Macrolide Resistance to Campylobacter jejuni Infection

S. Baqar, J. Lindow, K. Pierce, 2010, Journal of Clinical Microbiology.

Recrudescent Campylobacter jejuni Infection in an Immunocompetent Adult following Experimental Infection with a Well-Characterized Organism

K. Pierce, D. Tribble, B. Kirkpatrick, 2009, Clinical and Vaccine Immunology.

Construction and Characterization of Genetically Definedaro omp Mutants of Enterotoxigenic Escherichia coli and Preliminary Studies of Safety and Immunogenicity in Humans

D. Sack, T. D. Terry, A. Turner, 2001, Infection and Immunity.

Erratum 2: Construction and characterization of genetically defined aro omp mutants of enterotoxigenic Escherichia coli and preliminary studies of safety and immunogenicity in humans (Infection and Immunity (2001) 69: 8 (4969-4979))

D. Sack, T. D. Terry, A. Turner, 2001 .

A double-blind, placebo-controlled trial to evaluate the efficacy of PTL-003, an attenuated enterotoxigenic E. coli (ETEC) vaccine strain, in protecting against challenge with virulent ETEC.

M. Finucane, R. Sack, E. Hall, 2008, Vaccine.

Generation and Characterization of a Live Attenuated Enterotoxigenic Escherichia coli Combination Vaccine Expressing Six Colonization Factors and Heat-Labile Toxin Subunit B

Donna J. Freeman, J. C. Beavis, A. Turner, 2011, Clinical and Vaccine Immunology.

Screening and kinetic analysis of recombinant anti-CEA antibody fragments.

J. Link, R. Smith, Rodger G. Smith, 1995, Journal of immunological methods.

Comparative Safety and Immunogenicity of Two Attenuated Enterotoxigenic Escherichia coli Vaccine Strains in Healthy Adults

D. Sack, E. Hall, A. L. Bourgeois, 2006, Infection and Immunity.

Immunisation with phage displaying peptides representing single epitopes of the glycoprotein G can give rise to partial protective immunity to HSV-2.

W. Irving, A. Grabowska, R. Jennings, 2000, Virology.

Construction and Characterization of Genetically Definedaro omp Mutants of Enterotoxigenic Escherichia coli and Preliminary Studies of Safety and Immunogenicity in Humans

D. Sack, T. D. Terry, A. Turner, 2001, Infection and Immunity.

Antibody-Catalyzed Hydrolysis of an Unsubstituted Amide

P. M. Booth, A. Napper, R. Titmas, 1994 .

Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection

Arlo Z. Randall, D. Rasko, T. Vickers, 2019, npj Vaccines.

Human Experimental Challenge With Enterotoxigenic Escherichia coli Elicits Immune Responses to Canonical and Novel Antigens Relevant to Vaccine Development

Arlo Z. Randall, D. Rasko, T. Vickers, 2018, The Journal of infectious diseases.

Construction and Phase I Clinical Evaluation of the Safety and Immunogenicity of a Candidate Enterotoxigenic Escherichia coli Vaccine Strain Expressing Colonization Factor Antigen CFA/I

J. C. Beavis, N. Thomas, A. Turner, 2006, Infection and Immunity.

Nucleotide sequences of five anti‐lysozyme monoclonal antibodies.

A R Rees, A. Rees, M J Darsley, 1985, The EMBO journal.

Interaction of an immunodominant epitope with Ia molecules in T-cell activation.

L Adorini, G Doria, A Sette, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine with dmLT adjuvant protects human volunteers against virulent experimental ETEC challenge

D. Sack, S. Chakraborty, A. Fix, 2019, Vaccine.

Comparison of the antibody in lymphocyte supernatant (ALS) and ELISPOT assays for detection of mucosal immune responses to antigens of enterotoxigenic Escherichia coli in challenged and vaccinated volunteers.

D. Sack, R. Sack, E. Hall, 2006, Vaccine.

Stabilization of a Plasmid Coding for a Heterologous Antigen in Salmonella enterica Serotype Typhi Vaccine Strain CVD908-htrA by Using Site-Specific Recombination

A. Turner, M. Darsley, Jonathan C. Stephens, 2006, Infection and Immunity.

Attenuated Salmonella enterica Serovar Typhi Expressing Urease Effectively Immunizes Mice against Helicobacter pylori Challenge as Part of a Heterologous Mucosal Priming-Parenteral Boosting Vaccination Regimen

Donna J. Freeman, T. Monath, H. Kleanthous, 2002, Infection and Immunity.

Characterization of Two Campylobacter jejuni Strains for Use in Volunteer Experimental-Infection Studies

T. Read, C. Mason, O. Serichantalergs, 2008, Infection and Immunity.

Preclinical development of a novel Group B Streptococcus (GBS) vaccine candidate for maternal immunization based upon the alpha‐like protein family of GBS surface proteins (Alp)

M. Darsley, Per Fischer, G. Kitson, 2023, Birth defects research.

Safety and immunogenicity of the group B streptococcus vaccine AlpN in a placebo-controlled double-blind phase 1 trial

A. Pawłowski, M. Darsley, M. Gonzalez-Miro, 2023, iScience.

Determination of binding constants of diabodies directed against prostate‐specific antigen using electrochemiluminescence‐based immunoassays

J. Link, Rodger G. Smith, M. Darsley, 1996, Journal of molecular recognition : JMR.

Development of a fast-dissolving tablet formulation of a live attenuated enterotoxigenic E. coli vaccine candidate.

M. Lal, Dexiang Chen, D. Kristensen, 2013, Vaccine.

Modelling of the combining sites of three anti‐lysozyme monoclonal antibodies and of the complex between one of the antibodies and its epitope.

A. Rees, B. Sutton, P. Paz, 1986, The EMBO journal.

Three distinct epitopes within the loop region of hen egg lysozyme defined with monoclonal antibodies.

A R Rees, A. Rees, M J Darsley, 1985, The EMBO journal.

Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection

Arlo Z. Randall, D. Rasko, T. Vickers, 2019, npj Vaccines.

Conjugates of COL-1 monoclonal antibody and β-D-galactosidase can specifically kill tumor cells by generation of 5-fluorouridine from the prodrug β-D-galactosyl-5-fluorouridine

J. Kenten, R. Titmas, M. Darsley, 2007, Cell Biophysics.

Spectrophotometric quantitation of silver in X-ray film images and silver-stained electrophoresis gel bands.

R. Sanchez, M. Darsley, M. Martín, 1995, Analytical Biochemistry.

Mapping of Antigen Epitopes Interacting with Class II MHC Products and with the Antigen Receptor of T Lymphocytes

E. Appella, G. Doria, L. Adorini, 1987 .