L. Fraser

发表

ESHRE basic semen analysis courses 1995-1999: immediate beneficial effects of standardized training.

D. Mortimer, C. Barratt, L. Björndahl, 2002, Human reproduction.

Intracytoplasmic sperm injection (ICSI) in 2006: evidence and evolution.

L. Gianaroli, E. Diczfalusy, Jacques Cohen, 2007, Human reproduction update.

Capacitation state‐dependent changes in adenosine receptors and their regulation of adenylyl cyclase/cAMP

L. Fraser, S. Adeoya-Osiguwa, 2002, Molecular reproduction and development.

A mouse sperm decapacitation factor receptor is phosphatidylethanolamine-binding protein 1.

R. Gibbons, L. Fraser, S. Adeoya-Osiguwa, 2005, Reproduction.

Potassium ions modulate expression of mouse sperm fertilizing ability, acrosome reaction and hyperactivated motility in vitro.

L. Fraser, 1983, Journal of reproduction and fertility.

The effects of aging on in vitro fertilization of rabbit eggs and subsequent embryonic development.

L. Fraser, P. Dandekar, 1973, The Journal of experimental zoology.

Effects of estrogenic xenobiotics on human and mouse spermatozoa.

S. Milligan, Ergin Beyret, L. Fraser, 2006, Human reproduction.

Metabolic and surface events in fertilization.

K. Ahuja, L. Fraser, K. K. Ahuja, 1988, Gamete research.

Failures (with some successes) of assisted reproduction and gamete donation programs.

P. Crosignani, L. Gianaroli, B. Tarlatzis, 2013, Human reproduction update.

Role for Ca2+ channels in the signal transduction pathway leading to acrosomal exocytosis in human spermatozoa

E. Roldan, L. Fraser, C. O'Toole, 1996, Molecular reproduction and development.

First messenger regulation of mammalian sperm function via adenylyl cyclase/cAMP.

R. Baxendale, L. Fraser, S. Adeoya-Osiguwa, 2005, The Journal of reproduction and development.

First messenger regulation of capacitation via G protein-coupled mechanisms: a tale of serendipity and discovery.

R. Baxendale, L. Fraser, S. Adeoya-Osiguwa, 2003, Molecular human reproduction.

The effect of PMSG dose on the incidence of chromosomal anomalies in mouse embryos fertilized in vitro.

I. Maudlin, L. Fraser, 1977, Journal of reproduction and fertility.

The “switching on” of mammalian spermatozoa: Molecular events involved in promotion and regulation of capacitation

L. Fraser, 2010, Molecular reproduction and development.

Fertilization promoting peptide--a possible regulator of sperm function in vivo.

L. Fraser, S. Adeoya-Osiguwa, 2001, Vitamins and hormones.

Modulation of adenylyl cyclase by FPP and adenosine involves stimulatory and inhibitory adenosine receptors and g proteins

L. Fraser, S. Adeoya-Osiguwa, 1999, Molecular reproduction and development.

Interactions between a decapacitation factor and mouse spermatozoa appear to involve fucose residues and a GPI‐anchored receptor

L. Fraser, 1998, Molecular reproduction and development.

Ionic control of sperm function.

L. Fraser, LR Fraser, 1995, Reproduction, fertility, and development.

Ca2+‐Regulating mechanisms that modulate bull sperm capacitation and acrosomal exocytosis as determined by chlortetracycline analysis

K. Niwa, L. Fraser, L. R. Abeydeera, 1995, Molecular reproduction and development.

A possible role for Ca(2+)-ATPase in human sperm capacitation.

C. L. Mills, L. Fraser, S. DasGupta, 1994, Journal of reproduction and fertility.

Na+ requirements for capacitation and acrosomal exocytosis in mammalian sperm.

L. Fraser, 1994, International review of cytology.

A biphasic pattern of 45Ca2+ uptake by mouse spermatozoa in vitro correlates with changing functional potential.

L. Fraser, S. Adeoya-Osiguwa, 1993, Journal of reproduction and fertility.

Na(+)-requiring mechanisms modulate capacitation and acrosomal exocytosis in mouse spermatozoa.

L. Fraser, G. Umar, S. Sayed, 1993, Journal of reproduction and fertility.

Calcium channels play a pivotal role in the sequence of ionic changes involved in initiation of mouse sperm acrosomal exocytosis

L. Fraser, 1993, Molecular reproduction and development.

L. Fraser, C. McDermott, 1992, Journal of reproduction and fertility.

Characterization of a decapacitation factor associated with epididymal mouse spermatozoa.

R. Harrison, L. Fraser, J. E. Herod, 1990, Journal of reproduction and fertility.

Extended exposure to follicular fluid is required for significant stimulation of the acrosome reaction in human spermatozoa.

D. Edmonds, L. Fraser, K. Lindsay, 1989, Journal of reproduction and fertility.

Strontium supports capacitation and the acrosome reaction in mouse sperm and rapidly activates mouse eggs.

L. Fraser, 1987, Gamete research.

Minimum and maximum extracellular Ca2+ requirements during mouse sperm capacitation and fertilization in vitro.

L. Fraser, Lynn R. Fraser, 1987, Journal of reproduction and fertility.

Mouse sperm capacitation in vitro involves loss of a surface-associated inhibitory component.

L. Fraser, 1984, Journal of reproduction and fertility.

p-Aminobenzamidine, an acrosin inhibitor, inhibits mouse sperm penetration of the zona pellucida but not the acrosome reaction.

L. Fraser, 1982, Journal of reproduction and fertility.

Ca2+ Is Required for Mouse Sperm Capacitation and Fertilization In Vitro

L. Fraser, 1982 .

Mouse sperm genotype and the rate of egg penetration in vitro.

L. Fraser, L. M. Drury, 1976, The Journal of experimental zoology.

TCP‐11, the product of a mouse t‐complex gene, plays a role in stimulation of capacitation and inhibition of the spontaneous acrosome reaction

A. Talmor, R. K. Dudley, L. Fraser, 1997, Molecular reproduction and development.

The potential impact of novel investigational compounds on human fertility

L. Fraser, S. Adeoya-Osiguwa, 2006, Expert opinion on investigational drugs.

Adenosine analogues with specificity for A2 receptors bind to mouse spermatozoa and stimulate adenylate cyclase activity in uncapacitated suspensions.

L. Fraser, A. E. Duncan, 1993, Journal of reproduction and fertility.

Adenosine and its analogues, possibly acting at A2 receptors, stimulate mouse sperm fertilizing ability during early stages of capacitation.

L. Fraser, 1990, Journal of reproduction and fertility.

Physico-chemical properties of an agent that induces parthenogenesis in Rana pipiens eggs.

L. Fraser, 1971, The Journal of experimental zoology.

Dibutyryl cyclic AMP decreases capacitation time in vitro in mouse spermatozoa.

L. Fraser, 1981, Journal of reproduction and fertility.

A role for diacylglycerol in human sperm acrosomal exocytosis.

P. Hampton, E. Roldan, L. Fraser, 1996, Molecular human reproduction.

Sperm capacitation and the acrosome reaction.

L. Fraser, 1998, Human reproduction.

Protein kinase C activation during progesterone-stimulated acrosomal exocytosis in human spermatozoa.

E. Roldan, L. Fraser, C. O'Toole, 1996, Molecular human reproduction.

Protein Kinase C and Exocytosis in Mammalian Spermatozoa

E. Roldan, L. Fraser, 1998, Trends in Endocrinology & Metabolism.

New insights into possible factors contributing to male subfertility

L. Fraser, S. Adeoya-Osiguwa, 2005, Reproductive medicine and biology.

Mechanisms of action of angiotensin II on mammalian sperm function.

L. Fraser, S. Mededovic, 2005, Reproduction.

Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa

R. Baxendale, L. Fraser, 2003, Molecular reproduction and development.

Immunolocalization of multiple Gα subunits in mammalian spermatozoa and additional evidence for Gαs

R. Baxendale, L. Fraser, 2003 .

A fertilization promoting peptide (FPP)‐related tripeptide competitively inhibits responses to FPP: A cause of male subfertility?

A. Hanyaloglu, L. Fraser, S. M. Cockle, 1997, Molecular reproduction and development.

Divalent cations, capacitation and the acrosome reaction in human spermatozoa.

L. Fraser, C. E. Stock, 1989, Journal of reproduction and fertility.

Prolonged microvascular vasodilation induced by leukotriene B4 in human skin is cyclooxygenase independent.

J. Warren, H. Showell, L. Fraser, 1995, The Journal of pharmacology and experimental therapeutics.

Mammalian sperm phosphodiesterases and their involvement in receptor‐mediated cell signaling important for capacitation

R. Baxendale, L. Fraser, 2005, Molecular reproduction and development.

Case report: Percutaneous electrical neural field stimulation in two cases of sympathetically-mediated pain

Anna Woodbury, L. Fraser, 2017, F1000Research.

Multiple gestation pregnancy

Luca Gianaroli, David T. Baird, E. Diczfalusy, 2000 .

Europe the continent with the lowest fertility.

P. Crosignani, L. Gianaroli, W. Lutz, 2010, Human reproduction update.

Expression of capacitation-dependent changes in chlortetracycline fluorescence patterns in mouse spermatozoa requires a suitable glycolysable substrate.

L. Fraser, J. E. Herod, 1990, Journal of reproduction and fertility.

Molecular mechanisms during sperm capacitation

E. Baldi, W. Holt, H. Moore, 2005, Human fertility.

Mouse sperm capacitation assessed by kinetics and morphology of fertilization in vitro.

L. Fraser, 1983, Journal of reproduction and fertility.

The effect of Mycoplasma pulmonis on fertilization and preimplantation development in vitro of mouse eggs.

D. Taylor-Robinson, L. Fraser, 1977, Fertility and sterility.

Murine cytomegalovirus and fertility: potential sexual transmission and the effect of this virus on fertilization in vitro.

L. Fraser, P. A. Neighbour, 1978, Fertility and sterility.

New insights into possible causes of male infertility.

L. Fraser, 1999, Human reproduction.

The modulation of sperm function by fertilization promoting peptide.

L. Fraser, 1998, Human reproduction.

Phosphodiesterase activity of mouse sperm incubated under conditions that modulate fertilizing potential in vitro.

L. Fraser, N. Monks, 1987, Gamete research.

17beta-Estradiol and environmental estrogens significantly affect mammalian sperm function.

S. Markoulaki, S. Milligan, S A Adeoya-Osiguwa, 2003, Human reproduction.

Evidence for Ca2+‐dependent ATPase activity, stimulated by decapacitation factor and calmodulin, in mouse sperm

L. Fraser, S. Adeoya-Osiguwa, 1996, Molecular reproduction and development.

Angiotensin II stimulates cAMP production and protein tyrosine phosphorylation in mouse spermatozoa.

L. Fraser, S. Mededovic, 2004, Reproduction.

Fertilization promoting peptide and adenosine, acting as first messengers, regulate cAMP production and consequent protein tyrosine phosphorylation in a capacitation‐dependent manner

L. Fraser, Susan A. Adeoya‐Osiguwa, 2000, Molecular reproduction and development.

Albumin is required to support the acrosome reaction but not capacitation in mouse spermatozoa in vitro.

L. Fraser, 1985, Journal of reproduction and fertility.

The acrosome reaction in human sperm from men of proven fertility.

L. Fraser, C. E. Stock, 1987, Human reproduction.

Mechanisms controlling mammalian fertilization.

L. Fraser, 1984, Oxford reviews of reproductive biology.

Both fertilization promoting peptide and adenosine stimulate capacitation but inhibit spontaneous acrosome loss in ejaculated boar spermatozoa in vitro

T. Nagai, K. Niwa, L. Fraser, 2000, Molecular reproduction and development.

Fertilization promoting peptide: an important regulator of sperm function in vivo?

L. Fraser, 1998, Reviews of reproduction.

The relationship between sperm concentration and fertilization in vitro of mouse eggs.

L. Fraser, L. M. Drury, Lynn R. Fraser, 1975, Biology of reproduction.

Human oocyte-cumulus complexes stimulate the human acrosome reaction.

D. Edmonds, L. Fraser, K. Lindsay, 1989, Journal of reproduction and fertility.

Regulation of mammalian sperm capacitation by endogenous molecules.

R. Baxendale, R. Gibbons, L. Fraser, 2006, Frontiers in bioscience : a journal and virtual library.

A mouse sperm decapacitation factor receptor is phosphatidylethanolamine-binding protein 1.

R. Gibbons, L. Fraser, S. Adeoya-Osiguwa, 2005, Reproduction.

Cathine and norephedrine, both phenylpropanolamines, accelerate capacitation and then inhibit spontaneous acrosome loss.

L. Fraser, S. Adeoya-Osiguwa, 2005, Human reproduction.

Calcitonin acts as a first messenger to regulate adenylyl cyclase/cAMP and mammalian sperm function

L. Fraser, S. Adeoya-Osiguwa, 2003, Molecular reproduction and development.

Calcitonin, angiotensin II and FPP significantly modulate mouse sperm function.

G. Vinson, M. Pondel, L. Fraser, 2001, Molecular human reproduction.

FPP modulates mammalian sperm function via TCP‐11 and the adenylyl cyclase/cAMP pathway

L. Fraser, S. Adeoya-Osiguwa, R. Hosseini, 1998, Molecular reproduction and development.

Role of fertilization promoting peptide (FPP) in modulating mammalian sperm function.

L. Fraser, 1998, Frontiers in bioscience : a journal and virtual library.

Fertilization promoting peptide, a tripeptide similar to thyrotrophin-releasing hormone, stimulates the capacitation and fertilizing ability of human spermatozoa in vitro.

P. F. Watson, L. Fraser, S. M. Cockle, 1996, Human reproduction.

Consensus workshop on advanced diagnostic andrology techniques. ESHRE Andrology Special Interest Group.

J. Tesarik, D. Mortimer, C. Barratt, 1997, Human reproduction.

The effect of ruthenium red and concanavalin A on the vitelline surface of fertilized and unfertilized rabbit ova

L. Fraser, P. Dandekar, M. Gordon, 1975, The Anatomical record.

Motility patterns in mouse spermatozoa before and after capacitation.

L. Fraser, 1977, The Journal of experimental zoology.

A possible mechanism of action for fertilization promoting peptide, a TRH‐related tripeptide that promotes capacitation and fertilizing ability in mammalian spermatozoa

P. F. Watson, L. Fraser, S. M. Cockle, 1996, Molecular reproduction and development.

Stimulating effect of pyroglutamylglutamylprolineamide, a prostatic, TRH‐related tripeptide, on mouse sperm capacitation and fertilizing ability in vitro

P. F. Watson, L. Fraser, S. M. Cockle, 1994, Molecular reproduction and development.

Adenosine and gpp(NH)p modulate mouse sperm adenylate cyclase

L. Fraser, N. Monks, D. M. Stein, 1986 .

Cyclic AMP-dependent phosphorylation of epididymal mouse sperm proteins during capacitation in vitro: identification of an M(r) 95,000 phosphotyrosine-containing protein.

L. Fraser, A. E. Duncan, 1993, Journal of reproduction and fertility.

Genetic aspects of female reproduction.

P. Jacobs, L. Gianaroli, E. Diczfalusy, 2008, Human reproduction update.

L. Fraser, S. DasGupta, C. Mills, 1993, Journal of reproduction and fertility.

Fertilization and preimplantation development in vitro of mouse eggs obtained following stimulation with different doses of pregnant mare serum: a comparison of the responses in two strains.

L. Fraser, 1977, Differentiation; research in biological diversity.

Increased incidence of triploidy in embryos derived from mouse eggs fertilised in vitro

L. Fraser, G. Paton, L. M. Drury, 1976, Nature.

The relationship between zona digestion and cortical granule disappearance in rabbit eggs inseminated in vitro.

L. Fraser, P. Dandekar, 1975, Biology of Reproduction.

A glycolytic product is obligatory for initiation of the sperm acrosome reaction and whiplash motility required for fertilization in the mouse.

L. Fraser, P. Quinn, 1981, Journal of reproduction and fertility.

The effect of sperm and egg genotype on the incidence of chromosomal anomalies in mouse embryos fertilized in vitro.

I. Maudlin, L. Fraser, 1978, Journal of reproduction and fertility.

Analysis of aneuploidy in first-cleavage mouse embryos fertilized in vitro and in vivo.

I. Maudlin, L. Fraser, 1979, Environmental health perspectives.

Accelerated mouse sperm penetration in vitro in the presence of caffeine.

L. Fraser, 1979, Journal of reproduction and fertility.

Relationship between sperm concentration and the incidence of polyspermy in mouse embryos fertilized in vitro.

I. Maudlin, L. Fraser, 1978, Journal of reproduction and fertility.

Maternal age and the incidence of aneuploidy in first-cleavage mouse embryos.

I. Maudlin, L. Fraser, 1978, Journal of reproduction and fertility.

Fertilization of rabbit eggs in vitro without supplemental CO 2 in the atmosphere.

L. Fraser, P. Dandekar, 1973, Journal of reproduction and fertility.

Loss of cortical granules in rabbit eggs exposed to spermatozoa in vitro.

L. Fraser, P. Dandekar, M. Gordon, 1972, Journal of reproduction and fertility.

In vitro fertilization of tubal rabbit ova partially or totally denuded of follicular cells.

L. Fraser, P. Dandekar, R. Vaidya, 1971, Biology of reproduction.

Incidence of polyspermy in mouse eggs fertilized in vivo and in vitro after administration of progesterone and oestradiol.

I. Maudlin, L. Fraser, 1979, Journal of reproduction and fertility.

The role of small molecules in sperm capacitation.

L. Fraser, 2008, Theriogenology.

Functional analysis using chlortetracycline fluorescence and in vitro fertilization of frozen-thawed ejaculated boar spermatozoa incubated in a protein-free chemically defined medium.

W. Wang, K. Niwa, L. Fraser, 1995, Journal of reproduction and fertility.

Physiopathological determinants of human infertility.

L. Gianaroli, E. Diczfalusy, B. Tarlatzis, 2002, Human reproduction update.

L. Fraser, C. McDermott, 1992 .

Rate of fertilization in vitro and subsequent nuclear development as a function of the post-ovulatory age of the mouse egg.

L. Fraser, 1979, Journal of reproduction and fertility.

Effect of removal of epididymal secretions on fertilization in vitro of mouse eggs.

L. Fraser, L. M. Drury, 1976, Journal of reproduction and fertility.

Differing requirements for capacitation in vitro of mouse spermatozoa from two strains.

L. Fraser, 1977, Journal of reproduction and fertility.

Acrosome loss in human sperm incubated in vitro under capacitating conditions.

P. Mallett, L. Fraser, C. E. Stock, 1985, International journal of andrology.

Effect of bacterial neuraminidase on the fertilization of rabbit eggs in vitro.

L. Fraser, P. Dandekar, 1976, Journal of reproduction and fertility.

Birth defects and congenital health risks in children conceived through assisted reproduction technology (ART): a meeting report

R. Sharpe, P. Crosignani, L. Gianaroli, 2014 .

New insights into the t‐complex and control of sperm function

Keith Dudley, L. Fraser, Keith Dudley, 1999, BioEssays : news and reviews in molecular, cellular and developmental biology.

Modulation of mammalian sperm function by fertilization promoting peptide (FPP)

L. Fraser, 2009, Andrologia.

Adenylate cyclase activity of mouse sperm during capacitation in vitro: effect of calcium and a GTP analogue.

L. Fraser, N. Monks, D. M. Stein, 1986, International journal of andrology.

Protect us from poor-quality medical research.

J. Ioannidis, Gianluca Bontempi, E. Negri, 2018, Human reproduction.

A comparison of in-vitro fertilization of rabbit eggs using spermatozoa recovered from the uterus or vagina.

L. Fraser, P. Dandekar, 1976, Journal of reproduction and fertility.

Diagnosis and management of the infertile couple: missing information.

E. Diczfalusy, B. Tarlatzis, D. Baird, 2004, Human reproduction update.

The influence of social factors on gender health.

S. Peters, E. Negri, P. Crosignani, 2016, Human reproduction.

O-080. TCP-11, the product of a mouse t -complex gene, modulates sperm capacitation and fertilizing ability

A. Hanyaloglu, A. Talmor, L. Fraser, 1997 .

Effect of pentoxifylline and progesterone on human sperm capacitation and acrosomal exocytosis.

L. Fraser, C. O'Toole, S. DasGupta, 1994, Human reproduction.

Human sperm responses to calcitonin, angiotensin II and fertilization-promoting peptide in prepared semen samples from normal donors and infertility patients.

L. Fraser, Olufunmilayo O Osiguwa, 2004, Human reproduction.

Both taurine and albumin support mouse sperm motility and fertilizing ability in vitro but there is no obligatory requirement for taurine.

L. Fraser, 1986, Journal of reproduction and fertility.

Calcium channel antagonists modulate the acrosome reaction but not capacitation in mouse spermatozoa.

L. Fraser, K. McIntyre, Katherine McIntyre, 1989, Journal of reproduction and fertility.

Cyclic nucleotide metabolism in mouse epididymal spermatozoa during capacitation in vitro

L. Fraser, D. M. Stein, 1984 .

Inhibition of adenosine-metabolizing enzymes modulates mouse sperm fertilizing ability: a changing role for endogenously generated adenosine during capacitation.

L. Fraser, N. Monks, 1988, Gamete research.

Enzymes of adenosine metabolism in mouse sperm suspensions.

L. Fraser, N. Monks, 1988, Journal of reproduction and fertility.

Cathine, an amphetamine-related compound, acts on mammalian spermatozoa via beta1- and alpha2A-adrenergic receptors in a capacitation state-dependent manner.

L. Fraser, S. Adeoya-Osiguwa, 2006, Human reproduction.

Identification of functional α2- and β-adrenergic receptors in mammalian spermatozoa

R. Gibbons, L. Fraser, S. Adeoya-Osiguwa, 2006 .

VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 63

L. Fraser, S. Adeoya-Osiguwa, 2001 .

Mono-ovulatory cycles: A key goal in profertility programmes

R. Fanchin, L. Gianaroli, E. Diczfalusy, 2003 .

A comparison of fertility in vitro and in vivo after exposure of male mice to high environmental pressure

M. Halsey, L. Fraser, B. Wardley‐Smith, 1986 .

Fertilisation Promoting Peptide: a key player in male fertility/subfertility?

L. Fraser, 1997, Expert Opinion on Investigational Drugs.

Oncologic, Endocrine & Metabolic Fertilization promoting peptide: a key player in male fertility/subfertility?

L. Fraser, 1997 .

In vitro capacitation and fertilization.

L. Fraser, Lynn R. Fraser, 1993, Methods in enzymology.

Fertility and ageing.

L. Gianaroli, B. Tarlatzis, P. Devroey, 2005, Human reproduction update.

Chromosomal analysis of rabbits derived from eggs fertilized in vitro.

L. Fraser, G. Paton, R. Barnes, 1975, Journal of reproduction and fertility.

Cellular biology of capacitation and the acrosome reaction.

L. Fraser, 1995, Human reproduction.

Both taurine and albumin support mouse sperm motility and fertilizing ability in vitro but there is no obligatory requirement for taurine.

L. Fraser, 1986, Journal of reproduction and fertility.

The “switching on” of mammalian spermatozoa: Molecular events involved in promotion and regulation of capacitation

L. Fraser, 2010, Molecular reproduction and development.

ART: boon or bane?

L. Fraser, 2002, Nature cell biology.

Capacitation- and fertilization-related alterations in mouse sperm oxygen consumption.

L. Fraser, M. Lane, 1987, Journal of reproduction and fertility.