C. Jayne

Novel Quinoline-Based P2-P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease Inhibitors.

M. Rudd, P. Coleman, J. Vacca, 2014, ACS medicinal chemistry letters.

Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor.

Rebecca T. Ruck, Yongxin Han, J. Howe, 2016, ACS medicinal chemistry letters.

Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes.

Charles L. Jayne, B. Neustadt, W. Greenlee, 2011, Bioorganic & medicinal chemistry letters.

Proof of concept for the synthesis of [3.4.3.4] metacyclophane using a porphyrin as a scaffold

Charles L. Jayne, C. Jayne, 2008 .

Discovery of MK-8282 as a Potent G-Protein-Coupled Receptor 119 Agonist for the Treatment of Type 2 Diabetes.

B. Neustadt, Jinsong Hao, W. Greenlee, 2018, ACS medicinal chemistry letters.

Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with in Vivo Activity in Rodents.

Charles L. Jayne, F. Ujjainwalla, T. Akiyama, 2017, ACS medicinal chemistry letters.