Jie Xu

发表

Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors.

M. Fenaux, A. Ray, Joy Y. Feng, 2014, Bioorganic & medicinal chemistry letters.

Micellization of 4-Hydroxynaphthalimides: The Solvent-induced Aggregation and the Detection of Low-level Water in THF

Limin Wang, Yue Wu, Shengying Wu, 2016 .

A novel thiazolium type peptide coupling reagent for hindered amino acids

Peng Li, Jie Xu, 1999 .

1-Ethyl 2-Halopyridinium Salts, Highly Efficient Coupling Reagents for Hindered Peptide Synthesis both in Solution and the Solid-Phase

Jie Xu, P. Li, 2000 .

Highly Efficient Synthesis of Sterically Hindered Peptides Containing N-Methylated Amino Acid Residues using a Novel 1H-Benzimidazolium Salt

Peng Li, P. Li, Jie Xu, 2000 .

A Novel Thiazolium Type Peptide Coupling Reagent for Hindered Amino Acids.

P. Li, Jie Xu, 2000 .

BOMI — A novel peptide coupling reagent

Peng Li, P. Li, Jie Xu, 1999 .

Synthesis of N-Boc and N-Fmoc dipeptoids with nucleobase residues as peptoid nucleic acid monomers

Jie Xu, Yun Wu, Jing Liu, 2001 .

A divergent synthesis of 3,10-dialkylpicenes

Hiroki Mori, Y. Nishihara, X. Chen, 2015 .

Identification of potent type I MetAP inhibitors by simple bioisosteric replacement. Part 1: Synthesis and preliminary SAR studies of thiazole-4-carboxylic acid thiazol-2-ylamide derivatives.

F. Nan, Q. Ye, Jia Li, 2005, Bioorganic & medicinal chemistry letters.

Novel coupling reagents

Peng Li, Jie Xu, 2002 .

New and Highly Efficient Immonium Type Peptide Coupling Reagents: Synthesis, Mechanism and Application

P. Li, Jie Xu, 2000 .

HOBt and HOAt-derived immonium salts: new and highly efficient coupling reagents for peptide synthesis

P. Li, Jie Xu, 2000 .

Studies on enzymic peptide synthesis: I. Synthesis of tryptophane analogue of Leu-enkephalin†

Jie Xu, D. Feng, Yu Wang, 1985 .

Stereoselective construction of an unprecedented 7-8 fused ring system in micrandilactone a by [3,3]-sigmatropic rearrangement.

Zhen Yang, Y. Lan, Kai Wang, 2008, Organic letters.

Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides

A. Ray, Joy Y. Feng, Lijun Zhang, 2012, Bioorganic & Medicinal Chemistry Letters.

Practical synthesis of 1′-substituted Tubercidin C-nucleoside analogs

C. Kim, Sammy Metobo, A. Cho, 2012 .

Indole synthesis by palladium-catalyzed tandem allylic isomerization - furan Diels-Alder reaction.

P. Wipf, Jie Xu, 2017, Organic & biomolecular chemistry.

Chiral Tridentate P,N,N Ligands for Highly Enantioselective Copper‐Catalyzed Propargylic Amination with both Primary and Secondary Amines as Nucleophiles

C. Zhang, Jie Xu, Zhuo Zheng, 2012 .

Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.

William A. Lee, Xiaohong Liu, James M. Chen, 2006, Bioorganic & medicinal chemistry letters.

Synthesis of chiral peptide nucleic acids using Fmoc chemistry

Jie Xu, Yun Wu, 2001 .

Structure and Properties of One-dimensional Homometallic Complexes [Cu5(CN)5(5-ph-2,2′-bpy)3]n and [Cu(SCN)(5-ph-2,2′-bpy)]n (5-ph-2,2′-bpy = 5-Phenyl-2,2′-bipyridine)†

Minghui Zuo, S. Cui, Jie Xu, 2015 .

Selenium-catalyzed selective reactions of carbonyl derivatives: state-of-the-art and future challenges

Xi Xiao, Lei Yu, W. Fu, 2021 .

Nickel-Catalyzed Decarbonylative Alkylation of Aroyl Fluorides Assisted by Lewis-Acidic Organoboranes

Y. Nishihara, Jie Xu, Chen-an Wang, 2018, ACS omega.

Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease.

T. Appleby, W. Delaney, Ruby Z Cai, 2012, Bioorganic & medicinal chemistry letters.

Discovery of GS-9256: a novel phosphinic acid derived inhibitor of the hepatitis C virus NS3/4A protease with potent clinical activity.

W. Delaney, Ruby Z Cai, Xiaowu Chen, 2012, Bioorganic & medicinal chemistry letters.

Discovery of the first C-nucleoside HCV polymerase inhibitor (GS-6620) with demonstrated antiviral response in HCV infected patients.

W. Zhong, M. Fenaux, H. Ye, 2014, Journal of medicinal chemistry.

Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.

Huiling Yang, T. Appleby, M. Fenaux, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides

A. Ray, Joy Y. Feng, Lijun Zhang, 2012, Bioorganic & Medicinal Chemistry Letters.

Synthesis and characterization of 2'-C-Me branched C-nucleosides as HCV polymerase inhibitors.

A. Ray, Joy Y. Feng, D. Babusis, 2012, Bioorganic & medicinal chemistry letters.

Enantioselective Copper-Catalyzed Decarboxylative Propargylic Alkylation of Propargylic Esters with β-Keto Acids

Jie Xu, Xiangping Hu, C. Hou, 2014 .

Enantioselective copper-catalyzed decarboxylative propargylic alkylation of propargyl β-ketoesters with a chiral ketimine P,N,N-ligand.

Jie Xu, Xiangping Hu, De‐Yang Zhang, 2014, Angewandte Chemie.

On the cine substitution of 1,1-bis(tri-n-butylstannyl)ethenes in an intramolecular Stille reaction

C. Urch, P. Quayle, Jie Xu, 1998 .

Electrochemical oxidative radical cascade cyclization of olefinic amides and thiophenols towards the synthesis of sulfurated benzoxazines, oxazolines and iminoisobenzofurans

L. Sun, H. Alhumade, A. Lei, 2021, Green Chemistry.

Silylcarboxylic Acids as Bifunctional Reagents: Application in Palladium‐Catalyzed External‐CO‐Free Carbonylative Cross‐Coupling Reactions

T. Skrydstrup, Z. Lian, S. Kramer, 2020 .

In Situ Generation of Formaldehyde and Triphenylphosphine from (Hydroxymethyl)triphenylphosphonium and Its Application in Wittig Olefination

Jie Xu, Wenhua Huang, 2015 .

Highly diastereo- and enantioselective Cu-catalyzed [3 + 3] cycloaddition of propargyl esters with cyclic enamines toward chiral bicyclo[n.3.1] frameworks.

Jie Xu, Zhuo Zheng, Xiangping Hu, 2012, Journal of the American Chemical Society.

Efficient Manufacturing Process for the Selective Estrogen Receptor Degrader GDC-9545 (Giredestrant) via a Crystallization-Driven Diastereoselective Pictet–Spengler Condensation

F. Gosselin, Cheol K. Chung, Alec Fettes, 2021, Organic Process Research & Development.

Enantioselective synthesis of highly functionalized dihydrofurans through copper-catalyzed asymmetric formal [3+2] cycloaddition of β-ketoesters with propargylic esters.

Jie Xu, Xiangping Hu, De‐Yang Zhang, 2014, Angewandte Chemie.

1,1-Bis(trialkylstannyl)ethenes: Further investigations into their reactivity

C. Urch, P. Quayle, Jie Xu, 1998 .

Practical Synthesis of a 6-Triazolylazabicyclo[3.1.0]hexane

F. Gosselin, David B. Lao, R. Angelaud, 2018, Organic Process Research & Development.

5-Hydroxyindoles by intramolecular alkynol-furan diels-alder cycloaddition.

P. Wipf, M. Laporte, Jie Xu, 2013, The Journal of organic chemistry.

Chiral phosphine-phosphoramidite ligands for highly efficient Ir-catalyzed asymmetric hydrogenation of sterically hindered N-arylimines.

Jie Xu, Zhuo Zheng, Xiangping Hu, 2012, Organic letters.

Cyclic α-Alkoxyphosphonium Salts from (2-(Diphenylphosphino)phenyl)methanol and Aldehydes and Their Application in Synthesis of Vinyl Ethers and Ketones via Wittig Olefination.

Jie Xu, Wenhua Huang, Hong-Ying Rong, 2015, The Journal of organic chemistry.

Desilylation-Activated Propargylic Transformation: Enantioselective Copper-Catalyzed [3+2] Cycloaddition of Propargylic Esters with β-Naphthol or Phenol Derivatives.

Jie Xu, Xiangping Hu, De‐Yang Zhang, 2016, Angewandte Chemie.

Copper-catalyzed Regioselective Chloroamination of Alkenes with Chlorotrimethylsilane and N-Fluorobenzenesulfonimide under Microwave-assisted Conditions

Y. Nishihara, Jie Xu, Y. Ura, 2019, Chemistry Letters.

Synthesis of Fluoro-containing muramyl dipeptide analogs

Z. Wang, Jie Xu, 1998 .

Stereoselective Stille coupling reactions of 1,1-bis(trialkylstannyl)ethenes

C. Urch, P. Quayle, Jie Xu, 1998 .

Methyl 3,3-bis(trialkylstannyl)acrylates: An improved preparative procedure

C. Urch, P. Quayle, Jie Xu, 1998 .

Construction of Axially Chiral Arylborons via Atroposelective Miyaura Borylation.

Q. Song, Yong He, Kai Yang, 2021, Journal of the American Chemical Society.

Design and synthesis of a biotin-tagged photoaffinity probe of paeoniflorin.

F. Nan, Xing-zu Zhu, Wen-Wei Qiu, 2006, Bioorganic & medicinal chemistry letters.

Synthesis of Chiral Tryptamines via a Regioselective Indole Alkylation.

Cheol K. Chung, Jie Xu, Haiming Zhang, 2018, Organic letters.

Synthesis of fluoroalkylated muramyldipeptide analogs with lipophilic character

Jie Xu, Zhengfang Wang, 2002 .

Process Development Overcomes a Challenging Pd-Catalyzed C–N Coupling for the Synthesis of RORc Inhibitor GDC-0022

F. Gosselin, David B. Lao, Paroma Chakravarty, 2020 .

A Strecker approach to 2-substituted ethyl 5-aminothiazole-4-carboxylates

F. Gosselin, R. Angelaud, A. McClory, 2016 .

Electrochemical oxidative selenocyclization of olefinic amides towards the synthesis of iminoisobenzofurans

H. Alhumade, A. Lei, Lijun Lu, 2022, Organic Chemistry Frontiers.

Nickel-catalyzed reductive coupling reaction of monofluoroalkyl triflates with alkyl carboxylic acids toward the synthesis of α-alkyl-α-fluoro-alkylketones

Rui Wang, Y. Bi, Jie Xu, 2023, Chinese Chemical Letters.

First-Generation Asymmetric Synthesis of the Selective Estrogen Receptor Degrader GDC-9545 (Giredestrant) Featuring a Highly Efficient Pictet–Spengler Reaction and a C–N Coupling Reaction

F. Gosselin, Cheol K. Chung, Jie Xu, 2021, Organic Process Research & Development.

Copper-Catalyzed Asymmetric Formal [3 + 2] Cycloaddition of Propargylic Acetates with Hydrazines: Enantioselective Synthesis of Optically Active 2-Pyrazolines

Jie Xu, Xiangping Hu, De‐Yang Zhang, 2015 .

Current Synthetic Approaches to Peptide and Peptidomimetic Cyclization

P. Roller, P. Li, Jie Xu, 2002 .

Chiral Phosphine—Phosphoramidite Ligands for Highly Efficient Ir‐Catalyzed Asymmetric Hydrogenation of Sterically Hindered N‐Arylimines.

Jie Xu, Zhuo Zheng, Xiangping Hu, 2012 .

Peptide synthesis using pentafluorophenyl diphenylphosphate (FDP) as coupling reagent

Shao-qing Chen, Jie Xu, 2010 .

Catalytic AgF-Initiated Intramolecular 1,3-Sulfonyl Migration of gem-Difluorovinyl Sulfonates to α,α-Difluoro-β-ketosulfones.

Z. Lian, Haotian Sun, Jie Xu, 2020, Organic letters.

Activity‐Based Protein Profiling for Type I Methionine Aminopeptidase by Using Photo‐Affinity Trimodular Probes

F. Nan, Wen-Wei Qiu, Jie Xu, 2007, Chembiochem : a European journal of chemical biology.

Identification of potent type I MetAPs inhibitors by simple bioisosteric replacement. Part 2: SAR studies of 5-heteroalkyl substituted TCAT derivatives.

F. Nan, Q. Ye, L. Chen, 2005, Bioorganic & medicinal chemistry letters.

Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036.

F. Gosselin, S. Bachmann, R. Angelaud, 2023, Organic letters.

Stereoselective Synthesis of the IDO Inhibitor Navoximod.

F. Gosselin, H. Iding, S. Bachmann, 2022, Journal of Organic Chemistry.

The X-ray structures of HOBt-based immonium-type coupling reagents and the rearrangement of benzotriazolyl esters of Nα-protected amino acids or peptides: N- vs. O-substituted forms

P. Li, Jie Xu, 2001 .

Desilylation-Activated Propargylic Transformation: Enantioselective Copper-Catalyzed [3+2] Cycloaddition of Propargylic Esters with β-Naphthol or Phenol Derivatives.

Jie Xu, Xiangping Hu, De‐Yang Zhang, 2016, Angewandte Chemie.

Copper-Catalyzed Trifluoromethylthio-arylsulfonylation of Styrene Derivatives via the Insertion of Sulfur Dioxide.

Xuelei Ma, Z. Lian, Jie Xu, 2022, Organic letters.

Design and Synthesis of Matrix Metalloprotease Photoaffinity Trimodular Probes

F. Nan, Xin Li, Wen-Wei Qiu, 2009 .

5-Hydroxyindoles by intramolecular alkynol-furan diels-alder cycloaddition.

P. Wipf, M. Laporte, Jie Xu, 2013, The Journal of organic chemistry.

Indole synthesis by palladium-catalyzed tandem allylic isomerization - furan Diels-Alder reaction.

P. Wipf, Jie Xu, 2017, Organic & biomolecular chemistry.

Poly[(μ5-5-carboxylatotetrahydrofuran-2,3,4-tricarboxylic acid)sodium]

Hongsheng Shi, Kang-ying Shu, Wen‐Xiang Chai, 2009, Acta crystallographica. Section E, Structure reports online.

Cyclic α-Alkoxyphosphonium Salts from (2-(Diphenylphosphino)phenyl)methanol and Aldehydes and Their Application in Synthesis of Vinyl Ethers and Ketones via Wittig Olefination.

Jie Xu, Wenhua Huang, Hong-Ying Rong, 2015, The Journal of organic chemistry.