E. Jolicoeur

发表

Synthesis and optimization of a novel series of HCV NS3 protease inhibitors: 4-arylproline analogs.

M. Garneau, P. White, Jeff O'meara, 2013, Bioorganic & medicinal chemistry letters.

Discovery of the first thumb pocket 1 NS5B polymerase inhibitor (BILB 1941) with demonstrated antiviral activity in patients chronically infected with genotype 1 hepatitis C virus (HCV).

J. Duan, M. Garneau, S. LaPlante, 2012, Journal of medicinal chemistry.

Thiotetrazole alkynylacetanilides as potent and bioavailable non-nucleoside inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases.

J. Duan, M. Garneau, P. Bonneau, 2007, Bioorganic & medicinal chemistry letters.

Indole 5-carboxamide Thumb Pocket I inhibitors of HCV NS5B polymerase with nanomolar potency in cell-based subgenomic replicons (part 2): central amino acid linker and right-hand-side SAR studies.

Martin Poirier, J. Duan, M. Garneau, 2011, Bioorganic & medicinal chemistry letters.

N-Acetamideindolecarboxylic acid allosteric 'finger-loop' inhibitors of the hepatitis C virus NS5B polymerase: discovery and initial optimization studies.

J. Duan, M. Garneau, C. Brochu, 2010, Bioorganic & medicinal chemistry letters.

Enantioselective synthesis of spiropentanes from hydroxymethylallenes.

A. Charette, E. Jolicoeur, G. Bydlinski, 2001, Organic letters.

Generation of glycinyl radicals via a 1,5-hydrogen atom transfer reaction. Applications to γ-lactam formation

J. Rancourt, V. Gorys, E. Jolicoeur, 1998 .

Allosteric N-acetamide-indole-6-carboxylic acid thumb pocket 1 inhibitors of hepatitis C virus NS5B polymerase - Acylsulfonamides and acylsulfamides as carboxylic acid replacements

P. Kuhn, J. Duan, M. Garneau, 2013 .

From benzimidazole to indole-5-carboxamide Thumb Pocket I inhibitors of HCV NS5B polymerase. Part 1: indole C-2 SAR and discovery of diamide derivatives with nanomolar potency in cell-based subgenomic replicons.

J. Duan, M. Garneau, J. Gillard, 2011, Bioorganic & medicinal chemistry letters.