B. Chun

发表

Stereoselective synthesis of PSI-352938: a β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl-3',5'-cyclic phosphate nucleotide prodrug for the treatment of HCV.

M. Sofia, B. Ross, P. G. Reddy, 2011, The Journal of organic chemistry.

Discovery of PSI-353661, a Novel Purine Nucleotide Prodrug for the Treatment of HCV Infection.

M. Otto, C. Espiritu, A. Lam, 2011, ACS medicinal chemistry letters.

Synthesis and Biological Activity of 5′,9-Anhydro-3-Purine-ISONucleosides as Potential Anti-Hepatitis C Virus Agents

M. Otto, L. Stuyver, R. Schinazi, 2007, Nucleosides, nucleotides & nucleic acids.

Synthesis of 5′,9-anhydro-3-(β-d-ribofuranosyl)xanthine, and 3,5′-anhydro-xanthosine as potential anti-hepatitis C virus agents

L. Stuyver, R. Schinazi, Kyoichi A. Watanabe, 2005 .

Synthesis of enantiomerically pure cyclopropyl carbocyclic nucleosides

R. Schinazi, C. K. Chu, Yufen Zhao, 1994 .

N 4-Hydroxycytosine Dioxolane Nucleosides and Their Activity Against Hepatitis B Virus

M. Otto, L. Stuyver, R. Schinazi, 2005, Nucleosides, nucleotides & nucleic acids.

Current status of anti-HBV chemotherapy

C. K. Chu, Yongseok Choi, B. Chun, 1998, Archives of pharmacal research.

An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase.

W. Stec, M. Sofia, B. Ross, 2009, The Journal of organic chemistry.

2'-deoxy-2'-α-fluoro-2'-β-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938.

M. Otto, C. Espiritu, A. Lam, 2010, Bioorganic & Medicinal Chemistry Letters.

SYNTHESIS OF NOVEL D-2',3'-DIDEOXY-2',3'-ENDO-METHYLENE NUCLEOSIDES

C. K. Chu, B. Chun, J. Hong, 1998 .

Stereocontrolled syntheses of carbocyclic C-nucleosides and related compounds.

C. K. Chu, B. Chun, G. Song, 2001, The Journal of organic chemistry.

A practical synthesis of L-FMAU from L-arabinose.

Joon Hee Hong, C. K. Chu, K. Lee, 1999, Nucleosides & nucleotides.

Synthesis of Stable Isotope Labeled Analogs of the Anti-Hepatitis C Virus Nucleotide Prodrugs PSI-7977 and PSI-352938

C. Espiritu, M. Sofia, B. Ross, 2011, Nucleosides, nucleotides & nucleic acids.

Preparation de ribofuranosyle pyrimidines et purines a substitution 2'-fluoro-2'- alkyl- ou eventuellement a autre substitution ainsi que derives de celles-ci

B. Chun, Peiyuan Wang, 2005 .

Synthesis of 2',3'-dideoxy-3'-fluoro-L-ribonucleosides as potential antiviral agents from D-sorbitol.

R. Schinazi, Y. Cheng, C. K. Chu, 2000, Carbohydrate research.

Synthesis of 2′,3′-Dideoxy-3′-fluoro-L-ribonucleosides as Potential Antiviral Agents from D-Sorbitol.

R. Schinazi, C. K. Chu, B. Chun, 2000 .

Use of 2'-spirocyclic ethers in HCV nucleoside design.

C. Espiritu, A. Lam, M. Sofia, 2014, Journal of medicinal chemistry.

Unusual Olefin Formation by PhSe-F trans-Elimination

Kyoichi A. Watanabe, Junxing Shi, Jinfa Du, 2005, Nucleosides, nucleotides & nucleic acids.

Ring-expanded analogues of natural oxetanocin

V. Nair, B. Chun, J. Vadakkan, 2004 .

Enantiomeric syntheses of conformationally restricted D- and L-2', 3'-dideoxy-2',3'-endo-methylene nucleosides from carbohydrate chiral templates.

S. Olgen, C. K. Chu, M. Newton, 2000, The Journal of organic chemistry.

Synthesis of 5'-C-methyl-1',3'-dioxolan-4'-yl nucleosides.

L. Stuyver, S. Patterson, Kyoichi A. Watanabe, 2004, Bioorganic & medicinal chemistry letters.

β-D-2'-α-F-2'-β-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship study.

M. Otto, C. Espiritu, A. Lam, 2012, Bioorganic & medicinal chemistry letters.

Unusual Olefin Formation by PhSe‐F trans‐Elimination.

Kyoichi A. Watanabe, Junxing Shi, Jinfa Du, 2006 .

RING-EXPANDED ANALOGUES OF NATURAL OXETANOCIN: (+) AND (−) HYDROXYMETHYL ISODIDEOXYADENOSINE

V. Nair, B. Chun, J. Vadakkan, 2005, Nucleosides, Nucleotides & Nucleic Acids.

Enantiomeric Syntheses of Conformationally Restricted D‐ and L‐2′,3′‐Dideoxy‐2′,3′‐endo‐methylene Nucleosides from Carbohydrate Chiral Templates.

C. K. Chu, M. Newton, S. Ölgen, 2000 .

Asymmetric synthesis of car☐yclic C-nucleoside, (−)-9-deazaaristeromycin

C. K. Chu, B. Chun, 1999 .

Synthesis of 5′‐C‐Methyl‐1′,3′‐dioxolan‐4′‐yl Nucleosides.

L. Stuyver, S. Patterson, Kyoichi A. Watanabe, 2004 .

Synthesis and structure-activity relationships of novel anti-hepatitis C agents: N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one derivatives.

M. Otto, L. Stuyver, R. Schinazi, 2005, Journal of medicinal chemistry.

Discovery of β-D-2'-deoxy-2'-α-fluoro-4'-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases.

William A. Lee, R. Mackman, S. Swaminathan, 2015, Bioorganic & medicinal chemistry letters.

L-nucleoside analogues as potential antimalarials that selectively target Plasmodium falciparum adenosine deaminase.

A. M. Gero, C. K. Chu, A. Netting, 1999, Nucleosides & nucleotides.

An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase.

W. Stec, M. Sofia, B. Ross, 2009, The Journal of organic chemistry.