Giovanni Cambi

Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist useful tools for therapy of mnemonic damage.

C. Martini, C. Ghelardini, N. Galeotti, 2007, Bioorganic & medicinal chemistry.

Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modeling studies.

C. Martini, C. Ghelardini, M. Montali, 2008, Bioorganic & medicinal chemistry.

Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse agonism.

C. Martini, C. Ghelardini, M. Montali, 2009, Journal of medicinal chemistry.