G. Greig

发表

NOVEL 1,2-DIARYLCYCLOBUTENES : SELECTIVE AND ORALLY ACTIVE COX-2 INHIBITORS

D. Riendeau, C. Chan, W. Cromlish, 1996 .

Characterization of the cloned guinea pig leukotriene B4 receptor: comparison to its human orthologue.

Y. Boie, R. Stocco, S. Kargman, 1999, European journal of pharmacology.

2,3-Diarylthiophenes as selective EP1 receptor antagonists.

D. Denis, S. Kargman, G. O'neill, 2005, Bioorganic & medicinal chemistry letters.

Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold.

D. Denis, Y. Leblanc, G. O'neill, 2008, Bioorganic & medicinal chemistry letters.

Benzimidazoles as new potent and selective DP antagonists for the treatment of allergic rhinitis.

D. Denis, G. O'neill, Jennifer Wang, 2004, Bioorganic & medicinal chemistry letters.

Preferential inhibition of human phosphodiesterase 4 by ibudilast.

Y. Natsumeda, M. Salem, Zheng Huang, 2006, Life sciences.

Comparison between two classes of selective EP3 antagonists and their biological activities

C. Li, D. Denis, R. Gordon, 2006 .

Comparison between two classes of selective EP(3) antagonists and their biological activities.

Chun Xing Li, D. Denis, R. Gordon, 2006, Bioorganic & medicinal chemistry letters.

Structure-activity relationship of biaryl acylsulfonamide analogues on the human EP(3) prostanoid receptor.

D. Denis, R. Ruel, K. Metters, 2002, Bioorganic & medicinal chemistry letters.

Characterization of the human cysteinyl leukotriene CysLT1 receptor

Jilly F. Evans, C. Austin, B. Connolly, 1999, Nature.

Discovery of a potent and selective agonist of the prostaglandin EP4 receptor.

R. Young, D. Denis, K. Metters, 2003, Bioorganic & medicinal chemistry letters.

The C3a receptor antagonist SB 290157 has agonist activity.

A. Therien, S. Kargman, G. O'neill, 2005, Immunology letters.

Identification of a Potent and Selective Synthetic Agonist at the CRTH2 Receptor

D. Denis, G. O'neill, C. Beaulieu, 2005, Molecular Pharmacology.

Synthesis and biological evaluation of 5,6-diarylimidazo[2.1-b]thiazole as selective COX-2 inhibitors

D. Riendeau, P. Prasit, C. Brideau, 1997 .

Pyridazinones as selective cyclooxygenase-2 inhibitors.

D. Riendeau, P. Prasit, C. Brideau, 2003, Bioorganic & medicinal chemistry letters.

Discovery of a potent and selective agonist of the prostaglandin EP4 receptor.

R. Young, D. Denis, K. Metters, 2003, Bioorganic & medicinal chemistry letters.

A new structural variation on the methanesulfonylphenyl class of selective cyclooxygenase-2 inhibitors.

D. Riendeau, P. Prasit, C. Brideau, 1999, Bioorganic & medicinal chemistry letters.

Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).

R. Young, D. Denis, S. Kargman, 2007, Journal of medicinal chemistry.

2,3-Diarylcyclopentenones as orally active, highly selective cyclooxygenase-2 inhibitors.

R Gordon, D. Riendeau, P. Prasit, 1999, Journal of medicinal chemistry.

A new series of selective COX-2 inhibitors : 5,6-diarylthiazolo[3,2-b][1,2,4]triazoles

P. Prasit, C. Brideau, C. Chan, 1997 .

Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor

J. Falgueyret, M. Percival, D. Riendeau, 1997, British journal of pharmacology.

Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.

R Gordon, J. Falgueyret, M. Percival, 2001, The Journal of pharmacology and experimental therapeutics.

2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors.

R Gordon, R Fortin, D. Riendeau, 1998, Bioorganic & medicinal chemistry letters.

Potent and highly selective DP1 antagonists with 2,3,4,9-tetrahydro-1H-carbazole as pharmacophore.

D. Denis, G. O'neill, R. Zamboni, 2010, Bioorganic & Medicinal Chemistry Letters.

Identification of an indole series of prostaglandin D2 receptor antagonists.

R. Young, D. Denis, C. Brideau, 2006, Bioorganic & medicinal chemistry letters.

Structure–activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP3 antagonists

D. Denis, R. Gordon, R. Zamboni, 2005 .

Discovery of potent and selective DP1 receptor antagonists in the azaindole series.

D. Denis, Y. Leblanc, G. O'neill, 2009, Bioorganic & medicinal chemistry letters.

Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells.

Jilly F. Evans, J. Falgueyret, D. Riendeau, 1996, Biochemical pharmacology.

Structure–Activity Relationship of Biaryl Acylsulfonamide Analogues on the Human EP3 Prostanoid Receptor

D. Denis, R. Ruel, K. Metters, 2002 .

The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs.

C. Bayly, J. Falgueyret, M. Percival, 1997, Molecular pharmacology.

A New Series of Selective COX-2 Inhibitors: 5,6-Diarylthiazolo(3,2-b)( 1,2,4)triazoles.

P. Prasit, C. Brideau, C. Chan, 1997 .

Novel 1,2‐Diarylcyclobutenes: Selective and Orally Active COX‐2 Inhibitors.

D. Riendeau, W. Cromlish, R. Gordon, 1997 .