E. Wong

发表

NOVEL 1,2-DIARYLCYCLOBUTENES : SELECTIVE AND ORALLY ACTIVE COX-2 INHIBITORS

D. Riendeau, C. Chan, W. Cromlish, 1996 .

Characterization of autocrine inducible prostaglandin H synthase-2 (PGHS-2) in human osteosarcoma cells

D. Riendeau, B. Kennedy, S. Charleson, 1997, Inflammation Research.

5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase.

C. D. Richardson, M. Abramovitz, P. Vickers, 1993, European journal of biochemistry.

Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.

M. Crackower, D. Denis, R. Stocco, 2011, Bioorganic & medicinal chemistry letters.

The effect of 5-lipoxygenase-activating protein (FLAP) on substrate utilization by 5-lipoxygenase.

M. Abramovitz, P. Vickers, C. Deluca, 1997, Advances in experimental medicine and biology.

From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors.

P. Prasit, C. Chan, S. Charleson, 1997, Advances in experimental medicine and biology.

From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors

C. Bayly, D. Denis, P. Prasit, 1996 .

Pyridazinones as selective cyclooxygenase-2 inhibitors.

D. Riendeau, P. Prasit, C. Brideau, 2003, Bioorganic & medicinal chemistry letters.

Structures and properties of nonchelated, d0 alkyl alkene complexes of the type [Cp2ZrMe(alkene)]+: elusive intermediates during Ziegler-Natta polymerizations of alkenes.

F. Sauriol, T. Ziegler, T. Wondimagegn, 2009, Angewandte Chemie.

A new structural variation on the methanesulfonylphenyl class of selective cyclooxygenase-2 inhibitors.

D. Riendeau, P. Prasit, C. Brideau, 1999, Bioorganic & medicinal chemistry letters.

Antihypertensive pyrrolo[1,2-c]quinazolines and pyrrolo[1,2-c]quinazolinones.

E. Wong, Z. Hajos, V. Bandurco, 1981, Journal of medicinal chemistry.

Synthesis and biological evaluation of 2,3-diarylthiophenes as selective cox-2 inhibitors. part II: Replacing the heterocycle

D. Riendeau, P. Prasit, W. Cromlish, 1996 .

Synthesis and biological evaluation of 2,3-diarylthiophenes as selective Cox-2 and Cox-1 inhibitors

P. Prasit, D. Riendeau, D. Éthier, 1995 .

A new series of selective COX-2 inhibitors : 5,6-diarylthiazolo[3,2-b][1,2,4]triazoles

P. Prasit, C. Brideau, C. Chan, 1997 .

Cu(I) and Ag(I) complexes of 7-azaindolyl and 2,2'-dipyridylamino substituted 1,3,5-triazine and benzene: the central core impact on structure, solution dynamics and fluorescence of the complexes.

Suning Wang, Corey M. Seward, E. Wong, 2009, Dalton transactions.

SYNTHESIS AND BIOLOGICAL EVALUATION OF BOTH ENANTIOMERS OF L-761,000 AS INHIBITORS OF CYCLOOXYGENASE 1 AND 2

Yves Leblanc, Daniel Guay, Petpiboon Prasit, 1996 .

Correlation structure-activity in the bleaching properties of peracetylated carbohydrates

E. Wong, G. Descotes, A. Bouchu, 1996 .

Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor

J. Falgueyret, M. Percival, D. Riendeau, 1997, British journal of pharmacology.

Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.

R Gordon, J. Falgueyret, M. Percival, 2001, The Journal of pharmacology and experimental therapeutics.

Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays.

D. Riendeau, S. Charleson, W. Cromlish, 1997, Canadian journal of physiology and pharmacology.

Proximate functionality induced restricted rotation of a carbamate: 2,6‐Dicarbethoxy‐7‐methoxy‐5,6‐dihydropyrrolo[1,2‐c]quinazoline

E. Wong, M. Cotter, V. Bandurco, 1979 .

2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors.

R Gordon, R Fortin, D. Riendeau, 1998, Bioorganic & medicinal chemistry letters.

The reaction of epibromohydrin with hydroxyquinazolin‐2‐(1H)one derivatives. Novel oxazine formation

E. Wong, M. Cotter, Z. Hajos, 1979 .

Substituted heterocyclic analogs as selective COX-2 inhibitors in the flosulide class.

D. Riendeau, P. Prasit, C. Chan, 1999, Bioorganic & medicinal chemistry letters.

Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits.

D. Riendeau, P. Tagari, J. Q. Huang, 2001, Atherosclerosis.

Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells.

Jilly F. Evans, J. Falgueyret, D. Riendeau, 1996, Biochemical pharmacology.

Synthesis and Biological Evaluation of 2,3-Diarylthiophenes as Selective COX-2 Inhibitors. Part 2. Replacing the Heterocycle

D. Riendeau, P. Prasit, W. Cromlish, 1996 .

Conversion of Prostaglandin G/H Synthase-1 into an Enzyme Sensitive to PGHS-2-selective Inhibitors by a Double His513 → Arg and Ile523 → Val Mutation*

C. Bayly, D. Riendeau, J. Mancini, 1997, The Journal of Biological Chemistry.

A New Series of Selective COX-2 Inhibitors: 5,6-Diarylthiazolo(3,2-b)( 1,2,4)triazoles.

P. Prasit, C. Brideau, C. Chan, 1997 .

The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor.

M. Percival, D. Riendeau, B. Kennedy, 1999, Bioorganic & medicinal chemistry letters.

Synthesis of 5,6‐dimethoxyquinazolin‐2(1H)‐ones

R. Kanojia, J. Press, J. Lloyd, 1986 .

Novel 1,2‐Diarylcyclobutenes: Selective and Orally Active COX‐2 Inhibitors.

D. Riendeau, W. Cromlish, R. Gordon, 1997 .