Tae-Gyun Woo

发表

Human WRN is an intrinsic inhibitor of progerin, abnormal splicing product of lamin A

Su-Jin Lee, Bum-Joon Park, N. Ha, 2021, Scientific Reports.

Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome

Soo Yong Lee, Ji-Eun Kim, Bum-Joon Park, 2021, Communications biology.

Novel chemical inhibitor against SOD1 misfolding and aggregation protects neuron-loss and ameliorates disease symptoms in ALS mouse model

Yun-jeong Shin, E. Jung, Bum-Joon Park, 2021, Communications Biology.

p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation

Su-Jin Lee, Bum-Joon Park, N. Ha, 2019, Cell Death & Disease.

Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest

Hokeun Sun, Bum-Joon Park, N. Ha, 2017, Oncotarget.

Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation

Bum-Joon Park, N. Ha, Jinsook Ahn, 2022, Communications Biology.

Prevention effect of rare ginsenosides against stress-hormone induced MTOC amplification

Hokeun Sun, Bum-Joon Park, G. Song, 2016, Oncotarget.

Splicing Variants, Protein-Protein Interactions, and Drug Targeting in Hutchinson-Gilford Progeria Syndrome and Small Cell Lung Cancer

Bum-Joon Park, B. Kim, So-mi Kang, 2022, Genes.

The flavonoid morin alleviates nuclear deformation in aged cells by disrupting progerin-lamin A/C binding

J. Woo, Bum-Joon Park, N. Ha, 2021 .

Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype.

C. López-Otín, J. Freije, Ho-Yyoung Lee, 2016, The Journal of clinical investigation.

Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome

Bum-Joon Park, N. Ha, G. Song, 2021, Communications Biology.

Therapeutic Effect of Quinacrine, an Antiprotozoan Drug, by Selective Suppression of p-CHK1/2 in p53-Negative Malignant Cancers

Ho-Yyoung Lee, Bum-Joon Park, Youngri Jung, 2018, Molecular Cancer Research.

p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation

Su-Jin Lee, Bum-Joon Park, N. Ha, 2019, Cell Death & Disease.

Loss of NF2 Induces TGFβ Receptor 1–mediated Noncanonical and Oncogenic TGFβ Signaling: Implication of the Therapeutic Effect of TGFβ Receptor 1 Inhibitor on NF2 Syndrome

Ho-Yyoung Lee, Bum-Joon Park, N. Ha, 2018, Molecular Cancer Therapeutics.

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system

Bum-Joon Park, N. Ha, Sun-Hye Lee, 2013, Oncotarget.

Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson–Gilford Progeria Syndrome

Bum-Joon Park, B. Kim, So-mi Kang, 2023, Cells.

Conversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domain

B. Oh, J. Kim, J. Yeom, 2015, Cell Death and Disease.

Progerin, an Aberrant Spliced Form of Lamin A, Is a Potential Therapeutic Target for HGPS

Bum-Joon Park, So-mi Kang, Tae-Gyun Woo, 2023, Cells.