C. Wiel

发表

The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes

M. Bergo, D. Bernard, A. Griveau, 2020, Aging cell.

Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in Mice

M. Bergo, Marcus Henricsson, K. Le Gal, 2021, Antioxidants.

PLA2R1 mediates tumor suppression by activating JAK2.

M. Gelb, D. Bernard, Y. De Launoit, 2013, Cancer research.

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression

Michael P. Snyder, Zhihai Ma, B. Benayoun, 2017, Nature Communications.

Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape

D. Bernard, A. Augert, C. Wiel, 2016, Oncogene.

Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

D. Bernard, S. Aubert, L. Payen, 2014, Cell Death and Disease.

Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

D. Bernard, S. Aubert, L. Payen, 2014, Cell Death and Disease.

Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution

P. Dubus, D. Bernard, J. Guitton, 2016, Oncotarget.

Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis

I. Treilleux, D. Bernard, E. Lelièvre, 2013, Cell Death & Disease.

Tumor and Stem Cell Biology Potassium Channel KCNA 1 Modulates Oncogene-Induced Senescence and Transformation

N. Navaratnam, D. Bernard, D. Carling, 2013 .

senescence and transformation Potassium channel KCNA 1 modulates oncogene-induced

N. Navaratnam, D. Bernard, D. Carling, 2013 .

Potassium channel KCNA1 modulates oncogene-induced senescence and transformation.

N. Navaratnam, D. Carling, S. Aubert, 2013, Cancer research.

KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer

L. Akyürek, J. Nyman, V. Sayin, 2022, Cancers.

Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch

E. Alici, N. Kadri, P. Höglund, 2021, Life Science Alliance.

KRAS mutations predict better response to first-line monotherapy with pembrolizumab for patients with PD-L1high metastatic Non-Small Cell Lung Cancer: a retrospective study

J. Nyman, V. Sayin, H. Fagman, 2021, medRxiv.

Transport and senescence

D. Bernard, C. Wiel, 2015, Oncoscience.

Rho-GTPase dependent leukocyte interaction generates pro-inflammatory thymic Tregs and causes arthritis.

M. Bokarewa, V. Sayin, M. Brisslert, 2022, Journal of autoimmunity.

Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence

D. Bernard, N. Prevarskaya, H. Simonnet, 2014, Nature Communications.

Antioxidants can increase melanoma metastasis in mice

M. Bergo, L. Akyürek, J. Nilsson, 2015, Science Translational Medicine.

Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

M. Bergo, D. Bernard, J. Marvel, 2018, Aging cell.

Biotinylation of an acetylenic tricyclic bis(cyanoenone) lowers its potency as an NRF2 activator while creating a novel activity against BACH1.

R. Moreno, A. Dinkova-Kostova, L. de la Vega, 2022, Free radical biology & medicine.

The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity

Esben B. Svenningsen, A. Minassi, R. Moreno, 2022, Redox biology.

BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

M. Bergo, C. Kanduri, T. Mondal, 2019, Cell.

Antioxidants Promote Intestinal Tumor Progression in Mice

M. Bergo, L. Akyürek, Marcus Henricsson, 2021, Antioxidants.

PLA2R1 mediates tumor suppression by activating JAK2.

M. Gelb, D. Bernard, Y. De Launoit, 2013, Cancer research.

The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway

D. Bernard, P. Saintigny, F. van Coppenolle, 2018, Aging cell.

Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging

D. Bernard, S. Jaber, J. Marvel, 2021, Nature Communications.

Lysyl oxidases: emerging promoters of senescence escape, tumor initiation and progression

D. Bernard, C. Wiel, 2014 .

Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

D. Bernard, S. Aubert, L. Payen, 2014, Cell Death and Disease.

Glutamine Links Obesity to Inflammation in Human White Adipose Tissue.

M. McCarthy, M. Bergo, P. Arner, 2019, Cell metabolism.

KRAS mutations in combination with primary tumor size are not associated with a worse prognosis in early Non-Small Cell Lung Cancer

V. Sayin, H. Fagman, C. Wiel, 2023, medRxiv.

Targeting Krasg12c‐mutant cancer with a mutation‐specific inhibitor

M. Bergo, J. Christensen, P. Olson, 2020, Journal of internal medicine.

A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells

M. Bergo, S. Strömblad, M. Kashif, 2021, eLife.

SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity

M. Bergo, Yibin Kang, S. Ganesan, 2023, Oncogene.

Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein P

M. Schulze, H. Zischka, L. Schomburg, 2023, Nature communications.

Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor

A. Ståhlberg, Shawn Liang, S. Filges, 2023, iScience.

Lysyl oxidases: emerging promoters of senescence escape, tumor initiation and progression

D. Bernard, C. Wiel, 2014 .