I. Kill

发表

Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways

D. Tree, E. Makarov, C. Eskiw, 2019, Biogerontology.

Progeria, the nucleolus and farnesyltransferase inhibitors.

J. Bridger, I. Mehta, I. Kill, 2010, Biochemical Society transactions.

Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson–Gilford progeria syndrome fibroblasts

M. Goldberg, J. Bridger, C. Clements, 2018, Biogerontology.

Nuclear motors and nuclear structures containing A-type lamins and emerin: is there a functional link?

J. Bridger, I. Mehta, I. Kill, 2008, Biochemical Society transactions.

The nuclear lamina

H. Herrmann, J. Bridger, I. Kill, 2007, The FEBS journal.

The timing of the formation and usage of replicase clusters in S-phase nuclei of human diploid fibroblasts.

J. Bridger, C. Hutchison, G. Maldonado-Codina, 1991, Journal of cell science.

A p53-independent pathway regulates nucleolar segregation and antigen translocation in response to DNA damage induced by UV irradiation.

J. Boyle, I. Kill, R. Harry, 2004, Experimental cell research.

Cell cycle changes in A-type lamin associations detected in human dermal fibroblasts using monoclonal antibodies

E. Lane, C. Hutchison, R. Quinlan, 1997, Chromosome Research.

Towards a Drosophila model of Hutchinson-Gilford progeria syndrome.

D. Tree, J. Bridger, I. Kill, 2008, Biochemical Society transactions.

Heterogeneity of dimer excision in young and senescent human dermal fibroblasts

C. Parris, J. Boyle, I. Kill, 2005, Aging cell.

Internal lamin structures within G1 nuclei of human dermal fibroblasts.

J. Bridger, C. Hutchison, I. Kill, 1993, Journal of cell science.

Progeria Research Day at Brunel University

D. Tree, E. Makarov, C. Eskiw, 2011, Nucleus.

Changes in the nuclear distribution of DNA polymerase alpha and PCNA/cyclin during the progress of the cell cycle, in a cell-free extract of Xenopus eggs.

C. Hutchison, I. Kill, Christopher Hutchison, 1989, Journal of cell science.

DNA replication and cell cycle control in Xenopus egg extracts

C. Hutchison, C. Ford, I. Kill, 1989, Journal of Cell Science.

The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture.

R. Faragher, S. Shall, I. Kill, 1994, Journal of cell science.

The nuclear lamina

H. Herrmann, J. Bridger, I. Kill, 2007, The FEBS journal.

Analysis of UV-induced damage and repair in young and senescent human dermal fibroblasts using the comet assay

C. Hutchison, I. Kill, E. Al-Baker, 2005, Mechanisms of Ageing and Development.

Morphology Analyses of Human Carotid Plaque in Assessing Fibrous Cap Rupture Risk

Q. Long, S. Das, I. Kill, 2010 .

Localisation of the Ki-67 antigen within the nucleolus. Evidence for a fibrillarin-deficient region of the dense fibrillar component.

I. Kill, 1996, Journal of cell science.

Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts

W. Bickmore, S. Boyle, J. Bridger, 2000, Current Biology.

Alterations to Nuclear Architecture and Genome Behavior in Senescent Cells

J. Bridger, C. Clements, I. Mehta, 2007, Annals of the New York Academy of Sciences.

The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer

A. Harvey, Helen A. Foster, M. Knight, 2014 .

The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer.

A. Harvey, Helen A. Foster, M. Knight, 2014, Advances in experimental medicine and biology.

Interphase Chromosome Behavior in Normal and Diseased Cells

Catherine A. Moir, C. Eskiw, J. Bridger, 2013 .

Interphase Chromosomes in Replicative Senescence: Chromosome Positioning as a Senescence Biomarker and the Lack of Nuclear Motor-Driven Chromosome Repositioning in Senescent Cells

K. Meaburn, C. Eskiw, J. Bridger, 2021, Frontiers in Cell and Developmental Biology.

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

E. C. Schirmer, E. Makarov, R. Faragher, 2019, Genes, chromosomes & cancer.

Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells

Christopher H Eskiw, C. Eskiw, J. Bridger, 2011, Genome Biology.

Primary laminopathy fibroblasts display altered genome organization and apoptosis

E. Cabuy, G. Novelli, N. Lévy, 2007, Aging cell.

Different kinetics of senescence in human fibroblasts and peritoneal mesothelial cells.

A. Lloyd, I. Kill, S. Denyer, 1997, Experimental cell research.

Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication.

L. Cox, J. Bridger, C. Hutchison, 1994, Journal of cell science.

The in vitro kinetics of senescence of Fischer 344 rat embryo fibroblasts

R. Faragher, I. Kill, 2008, Biogerontology.

Senescent human diploid fibroblasts are able to support DNA synthesis and to express markers associated with proliferation.

S. Shall, I. Kill, 1990, Journal of cell science.

Rapamycin reduces fibroblast proliferation without causing quiescence and induces STAT5A/B-mediated cytokine production

Anthony Kusalik, Kimberly MacKay, Brett Trost, 2015, Nucleus.

The gene responsible for Werner syndrome may be a cell division "counting" gene.

R. Faragher, S. Shall, I. Kill, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Aging of Hutchinson–Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis

J. Bridger, I. Kill, 2004, Experimental Gerontology.

COMMENTARY Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication

L. Cox, J. Bridger, C. Hutchison, 1994 .

S‐Phase phosphorylation of lamin B2

C. Hutchison, I. Kill, 1995, FEBS letters.

Association of pKi-67 with satellite DNA of the human genome in early G1 cells

P. Lichter, J. Bridger, I. Kill, 2004, Chromosome Research.

Ageing research in the UK: plenty of proliferative potential. Cellular Senescence: the future of ageing. Oxford, United Kingdom, 16-17 July 1998.

I. Kill, 1998, Molecular medicine today.

Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways

D. Tree, E. Makarov, C. Eskiw, 2019, Biogerontology.

Nuclear motors and nuclear structures containing A-type lamins and emerin: is there a functional link?

J. Bridger, I. Mehta, I. Kill, 2008, Biochemical Society transactions.