D. Broek

发表

The catalytic domain of the mouse sos1 gene product activates Ras proteins in vivo and in vitro.

B. X. Liu, W. Wei, D. Broek, 1993, Oncogene.

Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins

M. Boguski, S. Powers, C. C. Lai, 1993, Molecular and cellular biology.

Phase variation in Pseudomonas

D. Broek, 2005 .

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

P. Nurse, D. Broek, Rachel Bartlett, 1991, Nature.

The adenylyl cyclase gene from Schizosaccharomyces pombe.

M. Wigler, J. Field, A. Vojtek, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Localization of the cellular expression pattern of cdc25NEF and ras in the juvenile rat brain.

M. Baudry, S. Schreiber, G. Tocco, 1993, Brain research. Molecular brain research.

VEGF receptor expression and signaling in human bladder tumors

Weicheng Wu, R. Mosteller, D. Broek, 2003, Oncogene.

Eukaryotic RAS proteins and yeast proteins with which they interact.

D. Broek, 1989, Current topics in microbiology and immunology.

Conservation and divergence of RAS protein function during evolution.

M. Wigler, T. Toda, S. Powers, 1985, Cold Spring Harbor symposia on quantitative biology.

Saccharomyces cerevisiae. competition between, RAS proteins from Guanine nucleotide activation of, and

M. Wigler, T. Kataoka, J. Field, 2012 .

5 a Gene of Yeast Required for a Function Modification of RAS Proteins and for Productio Mating Pheromone a-Factor

S. Michaelis, D. Broek, 2003 .

Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae

M. Wigler, T. Kataoka, J. Field, 1987, Molecular and cellular biology.

RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor

M. Wigler, I. Herskowitz, S. Powers, 1986, Cell.

EphB4 receptor tyrosine kinase is expressed in bladder cancer and provides signals for cell survival

J. Stein, D. Quinn, M. Buscarini, 2006, Oncogene.

Cloning and analysis of human cDNAs encoding a 140-kDa brain guanine nucleotide-exchange factor, Cdc25GEF, which regulates the function of Ras.

W. Wei, D. Broek, W. Park, 1994, Gene.

Generation of a monoclonal antibody to a cryptic site common to both integrin beta1 as well as gelatinase MMP9.

P. Brooks, Jinsong Xu, D. Broek, 2003, Hybridoma and hybridomics.

Identification and analysis of a DNA fragment from Saccharomyces kluyveri that can complement the loss of CDC25 function in Saccharomyces cerevisiae.

D. Broek, T. Prigozy, E. Gonzales, 1992, Gene.

Biochemical analysis of regulation of Vav, a guanine-nucleotide exchange factor for Rho family of GTPases.

R. Mosteller, D. Broek, J. Han, 2000, Methods in enzymology.

Control of Intramolecular Interactions between the Pleckstrin Homology and Dbl Homology Domains of Vav and Sos1 Regulates Rac Binding*

D Broek, J. Falck, J. Falck, 2000, The Journal of Biological Chemistry.

In vitro, Vav is a regulated guanine nucleotide dissociation inhibitor for Ras.

Jaewon Han, D. Broek, B. Das, 2002, Immunology letters.

Yeast cells can enter a quiescent state through G1, S, G2, or M phase of the cell cycle.

P. Nurse, W. Wei, D. Broek, 1993, Cancer research.

Identification of a dominant-negative mutation in the yeast CDC25 guanine nucleotide exchange factor for Ras

R. Mosteller, D. Broek, W. Park, 1997, Oncogene.

Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins

M. Wigler, A. Fujiyama, F. Tamanoi, 1985, Cell.

Studies in Saccharomyces cerevisiae

J. Nikawa, S. Cameron, T. Toda, 2013 .

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav.

M. White, Michael A. White, J. Falck, 1998, Science.

Influence ofGuanine Nucleotides on ComplexFormation between RasandCDC25Proteins

M. Boguski, S. Powers, D. Broek, 1993 .

The adenylyl cyclase-encoding gene from Saccharomyces kluyveri.

M. Wigler, D. Young, D. Broek, 1991, Gene.

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

M. Wigler, R. Lerner, J. Nikawa, 1988, Molecular and cellular biology.

In yeast, RAS proteins are controlling elements of adenylate cyclase

M. Wigler, J. Broach, T. Toda, 1985, Cell.

RAS proteins can induce meiosis in xenopus oocytes

M. Wigler, C. Birchmeier, D. Broek, 1985, Cell.

Identification of a mammalian gene structurally and functionally related to the CDC 25 gene of Saccharomyces cerevisiae ( signal transductlon / oncogenes / ras

P. Li, C. Dasgupta, R. Mosteller, 2022 .

Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae.

Peng Li, C. Dasgupta, Wen Wei, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway

M. Wigler, T. Toda, S. Powers, 1987, Cell.

Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity.

C. Der, L. Quilliam, W. Wei, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Studies of RAS function in the yeast Saccharomyces cerevisiae.

M. Wigler, J. Nikawa, S. Cameron, 1988, Cold Spring Harbor symposia on quantitative biology.

DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase

M. Wigler, T. Kataoka, D. Broek, 1985, Cell.

Distinct Subclasses of Small GTPases Interact with Guanine Nucleotide Exchange Factors in a Similar Manner

Gwo-Jen Day, G. Day, R. Mosteller, 1998, Molecular and Cellular Biology.

Involvement of the Switch 2 Domain of Ras in Its Interaction with Guanine Nucleotide Exchange Factors (*)

C. Der, J. Drugan, L. Quilliam, 1996, The Journal of Biological Chemistry.

GENETICS OF CELL PROLIFERATION

S. Cameron, T. Toda, D. Birnbaum, 2013 .

Two types of RAS mutants that dominantly interfere with activators of RAS

D Broek, M. Wigler, J. Camonis, 1994, Molecular and cellular biology.

Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant

S. Powers, D. Broek, E. Gonzales, 1991, Cell.

Lck regulates Vav activation of members of the Rho family of GTPases

C. Der, J. Westwick, L. Van Aelst, 1997, Molecular and cellular biology.

Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factors

D Broek, R. Mosteller, J Han, 1994, Molecular and cellular biology.

nucleotide exchange factors . critical for functional interaction with guanine Identification of residues of the Hras protein

R. Mosteller, D. Broek, J. Han, 2022 .

Influence of Guanine Nucleotides on Complex Formation between Ras and CDC 25 Proteins CHAR -

D. Broek, Chang-Wei Lai, 2022 .

Sphingosine Kinase Mediates Vascular Endothelial Growth Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases

Weicheng Wu, R. Mosteller, D. Broek, 2002, Molecular and Cellular Biology.

[15] Analysis of interaction between Ras and CDC25 guanine nucleotide exchange factor using yeast GAL4 two-hybrid system

R. Mosteller, D. Broek, W. Park, 1995 .

Expression and significance of vascular endothelial growth factor receptor 2 in bladder cancer.

S. Groshen, J. Stein, D. Quinn, 2006, The Journal of urology.

Sphingosine Kinase Protects Lipopolysaccharide-Activated Macrophages from Apoptosis

Weicheng Wu, R. Mosteller, D. Broek, 2004, Molecular and Cellular Biology.

Macrophages from Apoptosis Lipopolysaccharide-Activated Sphingosine Kinase Protects

Weicheng Wu, R. Mosteller, D. Broek, 2004 .

Amino acid residues in the CDC25 guanine nucleotide exchange factor critical for interaction with Ras

R. Mosteller, D. Broek, W. Park, 1994, Molecular and cellular biology.

EphB4 expression and biological significance in prostate cancer.

J. Pinski, R. Sutherland, S. Henshall, 2005, Cancer research.

EphB4 provides survival advantage to squamous cell carcinoma of the head and neck

U. Sinha, A. Schönthal, D. Crowe, 2006, International journal of cancer.

Inhibition of Tumor Cell Growth by Triton X-100 through Specific Effects on Cell-Cycle-Regulatory Components

A. Schönthal, D. Broek, L. Hassanieh, 2004, Journal of Biomedical Science.

Inhibition of tumor cell growth by Triton X-100 through specific effects on cell-cycle-regulatory components.

A. Schönthal, D. Broek, L. Hassanieh, 2004, Journal of biomedical science.