R. Nudischer

Characterization of a long-term mouse primary liver 3D tissue model recapitulating innate-immune responses and drug-induced liver toxicity

A. Hierlemann, K. Renggli, A. Roth, 2020, PloS one.

Network integration and modelling of dynamic drug responses at multi-omics levels

Fiona M. I. Hunter, S. Heymans, Ugis Sarkans, 2020, Communications Biology.

A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

L. Blank, S. Heymans, Ugis Sarkans, 2017, Archives of Toxicology.

Combining in vivo and organotypic in vitro approaches to assess the human relevance of Basimglurant (RG7090), a potential CAR activator.

A. Hierlemann, J. Hoflack, K. Renggli, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

DMSO induces drastic changes in human cellular processes and epigenetic landscape in vitro

J. Kleinjans, R. Schlapbach, R. Herwig, 2019, Scientific Reports.

Shared genetic factors for age at natural menopause in Iranian and European women.

J. Murabito, J. Perry, A. Brooks-Wilson, 2013, Human reproduction.

A Model‐Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs

L. Blank, C. Trautwein, J. Kleinjans, 2021, Clinical pharmacology and therapeutics.

Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds

Fiona M. I. Hunter, Christian Panse, Ugis Sarkans, 2022, Scientific Data.

Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling.

J. Kleinjans, L. Kuepfer, S. Niederer, 2018, Toxicology letters.

DMSO induces drastic changes in human cellular processes and epigenetic landscape in vitro

R Herwig, J. Kleinjans, R. Schlapbach, 2019, Scientific Reports.