S. Depauw

发表

Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia

I. Seuningen, M. David-Cordonnier, M. Lambert, 2019, Cancers.

Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model.

Daniel P. Sweat, P. Peixoto, W. Wilson, 2019, Journal of medicinal chemistry.

Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts

M. David-Cordonnier, S. Depauw, Gaëlle Savreux-Lenglet, 2015, International journal of molecular sciences.

Protein recognition of the S23906-1-DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH).

M. David-Cordonnier, G. Lenglet, S. Depauw, 2013, The Biochemical journal.

DNA Helix Destabilization by Alkylating Agents: From Covalent Bonding to DNA Repair

M. David-Cordonnier, G. Lenglet, S. Depauw, 2011 .

Anilides and quinolones with nitrogen-bearing substituents from benzothiophene and thienothiophene series: synthesis, photochemical synthesis, cytostatic evaluation, 3D-derived QSAR analysis and DNA-binding properties.

S. Tomić, M. Kralj, G. Karminski-Zamola,, 2014, European journal of medicinal chemistry.

Water-mediated binding of agents that target the DNA minor groove.

S. Neidle, W. Wilson, Arvind Kumar, 2011, Journal of the American Chemical Society.

Synthesis, antitumor activity, and mechanism of action of benzo[b]chromeno[6,5-g][1,8]naphthyridin-7-one analogs of acronycine.

B. Pfeiffer, Wen Tian, L. Kraus-Berthier, 2014, Journal of medicinal chemistry.

Influence of the Stereoisomeric Position of the Reactive Acetate Groups of the Benzo[b]Acronycine derivative S23906-1 on Its DNA Alkylation, Helix-Opening, Cytotoxic, and Antitumor Activities

C. Bailly, B. Pfeiffer, F. Tillequin, 2009, Molecular Pharmacology.

DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site.

W. Wilson, Arvind Kumar, D. Boykin, 2010, Journal of molecular biology.

In vitro anticancer activity, toxicity and structure-activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii.

R. Kiss, V. Mathieu, A. Evidente, 2011, Toxicology and applied pharmacology.

Novel phenyl and pyridyl substituted derivatives of isoindolines: Synthesis, antitumor activity and DNA binding features.

G. Karminski-Zamola,, S. Kraljević Pavelić, Nataša Ilić, 2014, European journal of medicinal chemistry.

Photochemical electrocyclisation of 3-vinylindoles to pyrido[2,3-a]-, pyrido[4,3-a]- and thieno[2,3-a]-carbazoles: design, synthesis, DNA binding and antitumor cell cytotoxicity.

M. David-Cordonnier, G. Lenglet, S. Depauw, 2009, European journal of medicinal chemistry.

Novel diamidino-substituted derivatives of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes: synthesis, antiproliferative and DNA binding properties.

P. Peixoto, K. Pavelić, G. Karminski-Zamola,, 2010, Journal of medicinal chemistry.

Synthesis, antitumor activity and DNA binding features of benzothiazolyl and benzimidazolyl substituted isoindolines.

G. Karminski-Zamola,, S. Kraljević Pavelić, Nataša Ilić, 2018, Bioorganic & medicinal chemistry.

Novel substituted benzothiophene and thienothiophene carboxanilides and quinolones: synthesis, photochemical synthesis, DNA-binding properties, antitumor evaluation and 3D-derived QSAR analysis.

Maja Aleksić, Sanja Tomić, Raja Nhili, 2012, Journal of medicinal chemistry.

Synthesis and biological evaluation of dialkylaminoalkylamino benzo[c][1,7] and [1,8]phenanthrolines as antiproliferative agents.

Soizic Prado, F. Tillequin, F. Porée, 2010, European journal of medicinal chemistry.

Novel amidino substituted benzimidazole and benzothiazole benzo[b]thieno-2-carboxamides exert strong antiproliferative and DNA binding properties.

M. Hranjec, G. Karminski-Zamola,, S. Kraljević Pavelić, 2017, European journal of medicinal chemistry.

Synthesis, cytotoxic activity, and DNA binding properties of antitumor cis-1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine cinnamoyl esters.

B. Pfeiffer, F. Tillequin, T. Gaslonde, 2009, Bioorganic & medicinal chemistry.

Synthesis, cytotoxic activity, and mechanism of action of furo[2,3-c]acridin-6-one and benzo[b]furo[3,2-h]acridin-6-one analogues of psorospermin and acronycine.

B. Pfeiffer, Marie-Christine Lallemand, F. Tillequin, 2008, Journal of medicinal chemistry.

The Unusual Monomer Recognition of Guanine-Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine

P. Peixoto, W. Wilson, Arvind Kumar, 2014, Biochemistry.

Targeting Transcription Factors for Cancer Treatment

Sabine Depauw, Mélanie Lambert, Samy Jambon, 2018, Molecules.

Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication

P. Peixoto, C. Bailly, W. Wilson, 2008, Nucleic acids research.

Structure‐Dependent Binding of Arylimidamides to the DNA Minor Groove

N. Campbell, S. Neidle, W. Wilson, 2014, Chembiochem : a European journal of chemical biology.

Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

P. Peixoto, Arvind Kumar, D. Boykin, 2012, Nucleic acids research.

Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair.

Rupesh K. Nanjunda, W. Wilson, Arvind Kumar, 2015, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents.

Soizic Prado, F. Tillequin, F. Porée, 2011, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of N‐Substituted Benzo[c]phenanthrolines and Benzo[c]phenanthrolinones as Antiproliferative Agents.

Soizic Prado, F. Tillequin, F. Porée, 2011 .

Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines.

R. Kiss, J. Kraus, T. Cresteil, 2010, European journal of medicinal chemistry.

New anticancer active and selective phenylene-bisbenzothiazoles: synthesis, antiproliferative evaluation and DNA binding.

K. Pavelić, G. Karminski-Zamola,, S. K. Pavelić, 2013, European journal of medicinal chemistry.

Structure‐Dependent Binding of Arylimidamides to the DNA Minor Groove

N. Campbell, S. Neidle, W. Wilson, 2014, Chembiochem : a European journal of chemical biology.

Induction of AML cell differentiation using HOXA9/DNA binding inhibitors as a potential therapeutic option for HOXA9‐dependent AML

C. Preudhomme, M. Bouhlel, M. Figeac, 2024, HemaSphere.