H. Holt

发表

Comparison of the modified Stokes' method of susceptibility testing with results obtained using MIC methods and British Society of Antimicrobial Chemotherapy breakpoints.

K. Bowker, A. MacGowan, J. Sunderland, 1998, The Journal of antimicrobial chemotherapy.

Activity of clindamycin against Staphylococcus aureus and Staphylococcus epidermidis from four UK centres.

I. Phillips, A. King, D. Reeves, 1991, The Journal of antimicrobial chemotherapy.

A critical assessment of the agar dilution chequerboard technique for studying in-vitro antimicrobial interactions using a representative beta-lactam, aminoglycoside and fluoroquinolone.

K. Bowker, A. MacGowan, M. Wootton, 1995, The Journal of antimicrobial chemotherapy.

Comparative pharmacodynamics of meropenem using an in-vitro model to simulate once, twice and three times daily dosing in humans.

K. Bowker, A. MacGowan, D. Reeves, 1998, Journal of Antimicrobial Chemotherapy.

Pharmacokinetics of cefotetan in patients with end-stage renal failure on maintenance dialysis.

D. Reeves, R. Yates, L. White, 1986, The Journal of antimicrobial chemotherapy.

A GUIDE TO SENSITIVITY TESTING

D. Greenwood, R. Wise, J. Andrews, 1991 .

In-vitro activity of HMR 3647 against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and beta-haemolytic streptococci.

K. Bowker, A. MacGowan, M. Wootton, 1999, The Journal of antimicrobial chemotherapy.

Activities of Moxifloxacin against, and Emergence of Resistance in, Streptococcus pneumoniae and Pseudomonas aeruginosa in an In Vitro Pharmacokinetic Model

K. Bowker, A. MacGowan, C. Rogers, 2003, Antimicrobial Agents and Chemotherapy.

Bay 12-8039, a new 8-methoxy-quinolone: comparative in-vitro activity with nine other antimicrobials against anaerobic bacteria.

K. Bowker, A. MacGowan, M. Wootton, 1997, The Journal of antimicrobial chemotherapy.

Cefaclor and amoxycillin in the treatment of infective exacerbations of chronic bronchitis.

M. Hodson, D. Reeves, H. Holt, 1983, The Journal of antimicrobial chemotherapy.

In-vitro studies with ciprofloxacin, a new 4-quinolone compound.

D. Reeves, L. White, H. Holt, 1984, The Journal of antimicrobial chemotherapy.

Therapeutic monitoring of antimicrobials: a summary of the information presented at the UK NEQAS for antibiotic Assays meeting for participants, October 1993.

A. MacGowan, D. Reeves, D. Warnock, 1995, The Journal of antimicrobial chemotherapy.

Assay of low trough serum gentamicin concentrations by fluorescence polarization immunoassay.

A. MacGowan, D. Reeves, A. Lovering, 1994, Journal of Antimicrobial Chemotherapy.

Resistance of bacterial pathogens to four aminoglycosides and six other antibacterials and prevalence of aminoglycoside modifying enzymes, in 20 UK centres.

D. Reeves, A. Lovering, H. Holt, 1988, The Journal of antimicrobial chemotherapy.

The Problem of Antibiotic Mixtures in Serum Samples

D. Reeves, H. Holt, 1976 .

In vitro activity of linezolid against Gram-positive isolates causing infection in continuous ambulatory peritoneal dialysis patients.

K. Bowker, A. MacGowan, M. Wootton, 2002, The Journal of antimicrobial chemotherapy.

The in-vitro degradation at 37°C of vancomycin in serum, CAPD fluid and phosphate-buffered saline

R. Finch, D. Reeves, A. Lovering, 1988 .

Activity in vitro of CGP 31608, a new penem antibacterial agent.

D. Reeves, H. Holt, M. Bywater, 1987, The Journal of antimicrobial chemotherapy.

Comparative in-vitro activity of Sch 34343, a new penem antibiotic.

D. Reeves, H. Holt, M. Bywater, 1985, The Journal of antimicrobial chemotherapy.

Pharmacodynamics of Gemifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model of Infection

K. Bowker, A. MacGowan, C. Rogers, 2001, Antimicrobial Agents and Chemotherapy.

Activity of Moxifloxacin, Administered Once a Day, against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model of Infection

K. Bowker, A. MacGowan, M. Wootton, 1999, Antimicrobial Agents and Chemotherapy.

Pharmacokinetic study of a sulfametopyrazine/trimethoprim combination (Kelfiprim) in human volunteers.

D. Reeves, H. Holt, D. Bullock, 1980, The Journal of antimicrobial chemotherapy.

Human metabolism of cefotaxime.

R. Bax, D. Reeves, L. White, 1980, The Journal of antimicrobial chemotherapy.

A new time-kill method of assessing the relative efficacy of antimicrobial agents alone and in combination developed using a representative beta-lactam, aminoglycoside and fluoroquinolone.

K. Bowker, A. MacGowan, M. Wootton, 1996, The Journal of antimicrobial chemotherapy.

Azlocillin and mezlocillin: laboratory studies of their properties, including comparison with the antibacterial activity of other antibiotics.

D. Reeves, H. Holt, M. Bywater, 1979, Arzneimittel-Forschung.

Antibacterial activity of the monobactam SQ 26,776 against antibiotic resistant enterobacteria, including Serratia spp.

D. Reeves, H. Holt, M. Bywater, 1981, The Journal of antimicrobial chemotherapy.

Ampicillin-aminoglycoside interaction studies using Listeria monocytogenes.

K. Bowker, A. MacGowan, M. Wootton, 1998, The Journal of antimicrobial chemotherapy.

Assessment of different antibacterial effect measures used in in vitro models of infection and subsequent use in pharmacodynamic correlations for moxifloxacin.

K. Bowker, A. MacGowan, C. Rogers, 2000, The Journal of antimicrobial chemotherapy.

Comparison of in-vitro pharmacodynamics of once and twice daily ciprofloxacin.

K. Bowker, A. MacGowan, C. Rogers, 1999, The Journal of antimicrobial chemotherapy.

The antibacterial efficacy of levofloxacin and ciprofloxacin against Pseudomonas aeruginosa assessed by combining antibiotic exposure and bacterial susceptibility.

A. MacGowan, M. Wootton, H. Holt, 1999, The Journal of antimicrobial chemotherapy.

The human pharmacokinetics of cefotaxime and its metabolites and the role of renal tubular secretion on their elimination

R. Bax, R. Ings, D. Reeves, 1985, Journal of Pharmacokinetics and Biopharmaceutics.

Evaluation of Innofluor fluorescence polarization immunoassay kits for the determination of serum concentrations of gentamicin, tobramycin, amikacin and vancomycin.lesassays@ukneqasaa.win-uk.net.

A. MacGowan, D. Reeves, L. White, 1997, The Journal of antimicrobial chemotherapy.

The activity of vancomycin against heterogeneous vancomycin-intermediate methicillin-resistant Staphylococcus aureus explored using an in vitro pharmacokinetic model.

K. Bowker, A. MacGowan, P. Bennett, 2001, The Journal of antimicrobial chemotherapy.

EPIDEMIC INFECTION BY A GENTAMICIN-RESISTANT STAPHYLOCOCCUS AUREUS IN THREE HOSPITALS

D. Reeves, D. Raghunath, H. Holt, 1976, The Lancet.

Microbiological assay of cefotaxime

D. Reeves, L. White, H. Holt, 1981 .

Effect of oral ciprofloxacin on the faecal flora of healthy volunteers

D. Reeves, L. White, H. Holt, 1986, European Journal of Clinical Microbiology.

The in vitro antibacterial activity of ceftriaxone in comparison with nine other antibiotics.

M. J. Hall, D. Reeves, A. Emmerson, 1985, Current medical research and opinion.

Cefoxitin sodium: a clinical and pharmacological study.

D. Reeves, P. Stocks, A. Bint, 1978, The Journal of antimicrobial chemotherapy.

Effect of probenecid on serum cefoxitin concentrations.

D. Reeves, A. Bint, H. Holt, 1977, The Journal of antimicrobial chemotherapy.

Evaluation of Innoﬂuor ﬂuorescence polarization immunoassay kits for the determination of serum concentrations of gentamicin, tobramycin, amikacin and vancomycin

L. White, A. Macgowan, D. Reeves, 1997 .

The effect of probenecid on the pharmacokinetics and distribution of cefoxitin in healthy volunteers.

D. Reeves, L. White, D. Thornhill, 1981, British journal of clinical pharmacology.

The activity of piperacillin/tazobactam against clinical isolates collected in 20 UK centres and the design of a disc test for susceptibility testing.

A. MacGowan, D. Reeves, H. Holt, 1993, The Journal of antimicrobial chemotherapy.

Comparative activity in vitro of cefotetan a new cephamycin antibiotic

D. Reeves, H. Holt, M. Bywater, 1983 .

An eight-year survey of the antimicrobial susceptibility patterns of 85,971 bacteria isolated from patients in a district general hospital and the local community.

A. MacGowan, N. Brown, D. Reeves, 1993, The Journal of antimicrobial chemotherapy.

The activity of cefpirome and ten other antibacterial agents against 2858 clinical isolates collected from 20 centres.

D. Reeves, H. Holt, M. Bywater, 1993, The Journal of antimicrobial chemotherapy.

In-vitro synergy testing of nine antimicrobial combinations against Listeria monocytogenes.

A. MacGowan, D. Reeves, H. Holt, 1990, The Journal of antimicrobial chemotherapy.

Synergy testing of macrolide combinations using the chequerboard technique.

K. Bowker, A. MacGowan, D. Reeves, 1993, The Journal of antimicrobial chemotherapy.

BAL 9141, a new broad-spectrum pyrrolidinone cephalosporin: activity against clinically significant anaerobes in comparison with 10 other antimicrobials.

K. Bowker, A. MacGowan, M. Wootton, 2002, The Journal of antimicrobial chemotherapy.

The in-vitro activity of trovafloxacin and nine other antimicrobials against 413 anaerobic bacteria.

K. Bowker, A. MacGowan, M. Wootton, 1996, Journal of Antimicrobial Chemotherapy.

In Vitro Activities of Y-688, a New 7-Substituted Fluoroquinolone, against Anaerobic Bacteria

K. Bowker, A. MacGowan, M. Wootton, 1998, Antimicrobial Agents and Chemotherapy.

Development of a novel assay method for colistin sulphomethate.

A. MacGowan, M. Wootton, H. Holt, 2005, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

In-vitro activity of cefpodoxime against 1834 isolates from domiciliary infections at 20 UK centres.

D. Reeves, H. Holt, M. Bywater, 1990, The Journal of antimicrobial chemotherapy.

Exploration of the in-vitro pharmacodynamic activity of moxifloxacin for Staphylococcus aureus and Streptococci of lancefield groups A and G.

K. Bowker, A. MacGowan, M. Wootton, 1999, The Journal of antimicrobial chemotherapy.

Bactericidal activity, post antibiotic effect and modified controlled effective regrowth time of meropenem at high concentrations.

K. Bowker, A. MacGowan, D. Reeves, 1996, The Journal of antimicrobial chemotherapy.

Cefuroxime resistance in Haemophilus influenzae

A. MacGowan, D. Reeves, S. McCulloch, 1992, The Lancet.

Chloramphenicol assay by EMIT.

D. Reeves, A. Lovering, L. White, 1988, Journal of Antimicrobial Chemotherapy.

Activity in vitro of tetroxoprim-sulphadiazine.

D. Reeves, H. Holt, M. Bywater, 1979, The Journal of antimicrobial chemotherapy.

Assay of serum teicoplanin concentrations in clinical specimens: a comparison of isocratic high performance liquid chromatography with polarisation fluoroimmunoassay and bioassay.

A. MacGowan, D. Reeves, A. Lovering, 1994, The Journal of antimicrobial chemotherapy.

Stabilization of cephalosporins in serum and plasma.

D. Reeves, H. Holt, M. Bywater, 1979, Journal of Antimicrobial Chemotherapy.

Bactericidal or bacteristatic effects of two sulphonamide plus trimethoprim preparations in human urine

D. Reeves, H. Holt, M. Bywater, 2005, Infection.

Resolution of antibiotic mixtures in serum samples by high-voltage electrophoresis.

D. Reeves, H. Holt, 1975, Journal of clinical pathology.

The in vitro activity of moxifloxacin against Haemophilus influenzae and Moraxella catarrhalis explored using a pharmacodynamic model.

K. Bowker, M. Wootton, H. Holt, 1999, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

The comparative inhibitory and bactericidal activities of meropenem and imipenem against Acinetobacter spp. and Enterobacteriaceae resistant to second generation cephalosporins.

K. Bowker, A. Hedges, D. Reeves, 1995, Journal of Antimicrobial Chemotherapy.

Pharmacokinetics of tetroxoprim and sulphadiazine in human volunteers.

D. Reeves, H. Holt, H. Vergin, 1979, The Journal of antimicrobial chemotherapy.