M. Gunduz

发表

Species-dependent hepatic and intestinal metabolism of selective oestrogen receptor degrader LSZ102 by sulphation and glucuronidation

M. Walles, Hilmar Schiller, Yan Ji, 2022, Xenobiotica; the fate of foreign compounds in biological systems.

Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: gender differences and implications for modulation of dopaminergic tone in the treatment of addictions.

A. Ho, L. Borg, M. Gunduz, 1999, The Journal of pharmacology and experimental therapeutics.

Models and Approaches Describing the Metabolism, Transport, and Toxicity of Drugs Administered by the Ocular Route

V. Sasseville, M. Walles, G. Camenisch, 2018, Drug Metabolism and Disposition.

Species Differences in the Biotransformation of an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist: The Effects of Distinct Glucuronide Metabolites on Overall Compound Disposition

C. L. Shaffer, T. O’Connell, Tim F. Ryder, 2010, Drug Metabolism and Disposition.

Nalmefene causes greater hypothalamic-pituitary-adrenal axis activation than naloxone in normal volunteers: implications for the treatment of alcoholism.

M. Kreek, A. King, A. Ho, 1998, Alcoholism, clinical and experimental research.

Using a Tritiated Compound to Elucidate Its Preclinical Metabolic and Excretory Pathways in Vivo: Exploring Tritium Exchange Risk

C. L. Shaffer, B. Thornburgh, G. Fate, 2006, Drug Metabolism and Disposition.

Oxidative ipso Substitution of 2,4-Difluoro-benzylphthalazines: Identification of a Rare Stable Quinone Methide and Subsequent GSH Conjugate

F. Lombardo, U. Argikar, Amanda L. Cirello, 2012, Drug Metabolism and Disposition.

In vitro ocular metabolism and bioactivation of ketoconazole in rat, rabbit and human.

U. Argikar, Jennifer L. Dumouchel, Amanda L. Cirello, 2017, Drug metabolism and pharmacokinetics.

Do We Need to Study Metabolism and Distribution in the Eye: Why, When, and Are We There Yet?

U. Argikar, Jennifer L. Dumouchel, Amanda L. Cirello, 2017, Journal of pharmaceutical sciences.

Ocular Metabolism of Levobunolol: Historic and Emerging Metabolic Pathways

Christine E. Dunne, U. Argikar, Mithat Gunduz, 2016, Drug Metabolism and Disposition.

Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies

U. Argikar, V. Hosagrahara, Suzie Ferreira, 2010, Drug Metabolism and Disposition.

BIOTRANSFORMATION OF A GABAA RECEPTOR PARTIAL AGONIST IN SPRAGUE-DAWLEY RATS AND CYNOMOLGUS MONKEYS: IDENTIFICATION OF TWO UNIQUE N-CARBAMOYL METABOLITES

R. Obach, C. L. Shaffer, T. O’Connell, 2005, Drug Metabolism and Disposition.

Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 2: Clearance

Franco Lombardo, Giuliano Berellini, F. Lombardo, 2013, Journal of clinical pharmacology.

Naltrexone biotransformation and incidence of subjective side effects: a preliminary study.

J. Volpicelli, C. O'brien, M. Kreek, 1997, Alcoholism: Clinical and Experimental Research.

Metabolic Enzyme Sulfotransferase 1A1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression.

Jeffrey A. Porter, K. Venkatesan, Christopher J. Wilson, 2015, Chemistry & biology.

Metabolic Enzyme Sulfotransferase 1 A 1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression Highlights

Jeffrey A. Porter, K. Venkatesan, Christopher J. Wilson, 2022 .

Hypothalamic-Pituitary-Adrenocortical (HPA) Axis Response and Biotransformation of Oral Naltrexone: Preliminary Examination of Relationship to Family History of Alcoholism

M. Kreek, A. King, A. Ho, 2002, Neuropsychopharmacology.

Microsoft Word-18199777-file00

U. Argikar, V. Hosagrahara, Suzie Ferreira, 2009 .

Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 1: Volume of Distribution at Steady State

Franco Lombardo, R Scott Obach, Giuliano Berellini, 2013, Journal of clinical pharmacology.

New Perspectives on Acyl Glucuronide Risk Assessment in Drug Discovery: Investigation of In vitro Stability, In situ Reactivity, and Bioactivation

U. Argikar, Jennifer L. Dumouchel, Amanda L. Cirello, 2018, Drug metabolism letters.

Metabolism and Disposition of a γ-Aminobutyric Acid Type A Receptor Partial Agonist in Humans

K. Venkatakrishnan, A. Burstein, A. Vaz, 2008, Drug Metabolism and Disposition.

In vitro-in vivo correlation for intrinsic clearance for CP-409,092 and sumatriptan: a case study to predict the in vivo clearance for compounds metabolized by monoamine oxidase

R. Obach, S. Harriman, A. Kamel, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Metabolism and Disposition of a Selective α7 Nicotinic Acetylcholine Receptor Agonist in Humans

Christopher L. Shaffer, R. Scialis, C. L. Shaffer, 2007, Drug Metabolism and Disposition.

Metabolism and disposition of a selective alpha(7) nicotinic acetylcholine receptor agonist in humans.

R. Scialis, C. L. Shaffer, A. Fang, 2007, Drug metabolism and disposition: the biological fate of chemicals.

Investigation of Ocular Bioactivation Potential and the Role of Cytochrome P450 2D Enzymes in Rat.

U. Argikar, Jennifer L. Dumouchel, Amanda L. Cirello, 2018, Drug metabolism letters.

Basal total opioid peptide release in the striatum of rats with cholestasis from bile duct resection: a study by the use of in vivo microdialysis.

N. Maidment, M. Kreek, A. Ho, 1997, Life sciences.

Metabolism and Excretion of Therapeutic Peptides: Current Industry Practices, Perspectives, and Recommendations

Joe R. Cannon, C. Hilgendorf, M. Gunduz, 2023, Drug Metabolism and Disposition.

Models and Approaches Describing the Metabolism, Transport, and Toxicity of Drugs Administered by the Ocular Route

V. Sasseville, M. Walles, G. Camenisch, 2018, Drug Metabolism and Disposition.

Genotoxicity of 4-(piperazin-1-yl)-8-(trifluoromethyl)pyrido[2,3-e][1,2,4] triazolo[4,3-a]pyrazine, a Potent H4 Receptor Antagonist for the Treatment of Allergy: Evidence of Glyoxal Intermediate Involvement.

P. Klimko, U. Argikar, Jennifer L. Dumouchel, 2018, Drug metabolism letters.