S. Duan

发表

Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.

C. Guillemette, D. Greenblatt, L. V. von Moltke, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo.

D. Greenblatt, J. Harmatz, R. Shader, 1996, Journal of clinical psychopharmacology.

Venlafaxine and metabolites are very weak inhibitors of human cytochrome P450-3A isoforms

D. Greenblatt, J. Harmatz, R. Shader, 1997, Biological Psychiatry.

Cytochrome P-450 2 B 6 Is Responsible for Interindividual Variability of Propofol Hydroxylation by Human Liver Microsomes

D. Greenblatt, K. Venkatakrishnan, L. Hesse, 2000 .

Synthesis and evaluation of hydrolyzable hyaluronan-tethered bupivacaine delivery systems.

D. Gianolio, Robert J. Miller, L. Avila, 2005, Bioconjugate chemistry.

ATAZANAVIR: EFFECTS ON P-GLYCOPROTEIN TRANSPORT AND CYP3A METABOLISM IN VITRO

D. Greenblatt, L. V. von Moltke, E. S. Perloff, 2005, Drug Metabolism and Disposition.

In vitro biotransformation of phenacetin to acetaminophen: Metabolic inhibition by antidepressants

D. Greenblatt, J. Harmatz, R. Shader, 1996 .

Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine

D. Greenblatt, J. Harmatz, R. Shader, 1996, Psychopharmacology.

ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY

D. Greenblatt, S. Wrighton, R. Evans, 2005, Drug Metabolism and Disposition.

Effect of lipophilicity on drug distribution and elimination: Influence of obesity

D. Greenblatt, J. Harmatz, Christina R. Chow, 2021, British journal of clinical pharmacology.

Race, Gender, and Genetic Polymorphism Contribute to Variability in Acetaminophen Pharmacokinetics, Metabolism, and Protein-Adduct Concentrations in Healthy African-American and European-American Volunteers

D. Greenblatt, J. Harmatz, M. Court, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Atazanavir: Effects on P-gp transport and CYP3A metabolism in vitro

D. Greenblatt, E. S. Perloff, P. Skolnik, 2005 .

CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.

D. Greenblatt, R. Shader, K. Venkatakrishnan, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Characterization of six in vitro reactions mediated by human cytochrome P450: application to the testing of cytochrome P450-directed antibodies.

D. Greenblatt, J. Harmatz, R. Shader, 1996, Pharmacology.

Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations.

D. Greenblatt, J. Harmatz, R. Shader, 1999, British journal of clinical pharmacology.

Midazolam Hydroxylation by Human Liver Microsomes In Vitro: Inhibition by Fluoxetine, Norfluoxetine, and by Azole Antifungal Agents

D. Greenblatt, J. Harmatz, R. Shader, 1996, Journal of clinical pharmacology.

Cytochrome P-450 2B6 Is Responsible for Interindividual Variability of Propofol Hydroxylation by Human Liver Microsomes

D. Greenblatt, K. Venkatakrishnan, L. Hesse, 2001, Anesthesiology.

Mechanism of cytochrome P450‐3A inhibition by ketoconazole

Karthik Venkatakrishnan, David J Greenblatt, D. Greenblatt, 2011, The Journal of pharmacy and pharmacology.

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole.

J S Harmatz, D J Greenblatt, D. Greenblatt, 1996, The Journal of pharmacology and experimental therapeutics.

In Vitro Prediction of the Terfenadine‐Ketoconazole Pharmacokinetic Interaction

D. Greenblatt, J. Harmatz, R. Shader, 1994, Journal of clinical pharmacology.

Serotonin (5-hydroxytryptamine) glucuronidation in vitro : assay development, human liver microsome activities and species differences

D. Greenblatt, L. V. von Moltke, J. Sudmeier, 2003, Xenobiotica; the fate of foreign compounds in biological systems.

Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism.

D. Greenblatt, L. V. von Moltke, C. Patten, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms.

D. Greenblatt, J. Miners, P. Mackenzie, 2001, The Journal of pharmacology and experimental therapeutics.

Inhibition of Human Cytochrome P450 Isoforms by Nonnucleoside Reverse Transcriptase Inhibitors

D. Greenblatt, J. Harmatz, R. Shader, 2001, Journal of clinical pharmacology.

Protease Inhibitors as Inhibitors of Human Cytochromes P450: High Risk Associated with Ritonavir

D. Greenblatt, J. Harmatz, R. Shader, 1998, Journal of clinical pharmacology.

Potent mechanism-based inhibition of human CYP3A in vitro by amprenavir and ritonavir: comparison with ketoconazole

D. Greenblatt, L. V. von Moltke, S. Duan, 2000, European Journal of Clinical Pharmacology.

Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo.

J S Harmatz, D J Greenblatt, D. Greenblatt, 1994, The Journal of pharmacology and experimental therapeutics.

Human cytochromes mediating N-demethylation of fluoxetine in vitro

D. Greenblatt, J. Harmatz, R. Shader, 1997, Psychopharmacology.

The UDP-Glucuronosyltransferase (UGT) 1A Polymorphism c.2042C>G (rs8330) Is Associated with Increased Human Liver Acetaminophen Glucuronidation, Increased UGT1A Exon 5a/5b Splice Variant mRNA Ratio, and Decreased Risk of Unintentional Acetaminophen-Induced Acute Liver Failure

William M. Lee, C. Guillemette, D. Greenblatt, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Inhibition of desipramine hydroxylation (Cytochrome P450-2D6) in vitro by quinidine and by viral protease inhibitors: relation to drug interactions in vivo.

D. Greenblatt, J. Harmatz, R. Shader, 1998, Journal of pharmaceutical sciences.

Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6.

David J Greenblatt, D. Greenblatt, L. V. von Moltke, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Inhibition of triazolam clearance by macrolide antimicrobial agents: In vitro correlates and dynamic consequences

D. Greenblatt, J. Harmatz, R. Shader, 1998, Clinical pharmacology and therapeutics.

Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants.

D. Greenblatt, J. Harmatz, R. Shader, 1995, Journal of clinical psychopharmacology.

Appetite suppressant drugs as inhibitors of human cytochromes P450: in vitro inhibition of P450-2D6 by D- and L-fenfluramine, but not phentermine.

J S Harmatz, D J Greenblatt, D. Greenblatt, 1998, Journal of clinical psychopharmacology.

Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects

D. Greenblatt, J. Harmatz, R. Shader, 1999, Biological Psychiatry.

Kinetic Characterization and Identification of the Enzymes Responsible for the Hepatic Biotransformation of Adinazolam and N‐Desmethyladinazolam in Man

D. Greenblatt, R. Shader, K. Venkatakrishnan, 1998, The Journal of pharmacy and pharmacology.

Role of CYP3A and CYP2E1 in Alcohol-Mediated Increases in Acetaminophen Hepatotoxicity: Comparison of Wild-Type and Cyp2e1(–/–) Mice

D. Greenblatt, S. Wrighton, F. Gonzalez, 2007, Drug Metabolism and Disposition.