A. Kakefuda

发表

Nucleosides and nucleotides. 120. Stereoselective radical deoxygenation of tert-alcohols in the sugar moiety of nucleosides: synthesis of 2′,3′-dideoxy-2′-C-methyl- -2′-C-ethynyl-β-d-threo-pentofuranosyl pyrimidines and adenine as potential antiviral and antitumor agents☆

A. Matsuda, Takuma Sasaki, A. Kakefuda, 1993 .

Welwitindolinone C synthetic studies. Construction of the welwitindolinone carbon skeleton via a transannular nitrone cycloaddition.

S. Reisman, B. Stoltz, R. Vaswani, 2010, Tetrahedron.

Synthesis and Pharmacological Evaluation of 5-(4-Biphenyl)-3-methyl-4-phenyl-1,2,4-triazole Derivatives as a Novel Class of Selective Antagonists for the Human Vasopressin V1A Receptor

J. Tsukada, S. Tsukamoto, S. Sakamoto, 2002 .

Synthesis and pharmacological evaluation of 5-(4-biphenyl)-3-methyl-4-phenyl-1,2,4-triazole derivatives as a novel class of selective antagonists for the human vasopressin V(1A) receptor.

J. Tsukada, S. Tsukamoto, S. Sakamoto, 2002, Journal of medicinal chemistry.

Spiro-substituted piperidines as neurokinin receptor antagonists. II. Syntheses and NK2 receptor-antagonistic activities of N-[2-aryl-4-(spiro-substituted piperidin-1'-yl)butyl]carboxamides.

M. Takeuchi, Y. Isomura, T. Shibanuma, 1998, Chemical & pharmaceutical bulletin.

Synthesis and structure-activity relationships of benzyloxyphenyl derivatives as a novel class of NCX inhibitors: effects on heart failure.

Hiroyoshi Yamada, S. Sakamoto, A. Kakefuda, 2005, Bioorganic & medicinal chemistry.

Discovery of N-(3-{4-[(3-fluorobenzyl)oxy]phenoxy}propyl)-2-pyridin-4-ylacetamide as a potent and selective reverse NCX inhibitor.

Hiroyoshi Yamada, S. Sakamoto, A. Kakefuda, 2005, Chemical & pharmaceutical bulletin.

Discovery of an N-(2-aminopyridin-4-ylmethyl)nicotinamide derivative: a potent and orally bioavailable NCX inhibitor.

Hiroyoshi Yamada, S. Sakamoto, A. Kakefuda, 2005, Bioorganic & medicinal chemistry.

Discovery of 4,5-diphenyl-1,2,4-triazole derivatives as a novel class of selective antagonists for the human V(1A) receptor.

S. Tsukamoto, S. Sakamoto, A. Kakefuda, 2002, Bioorganic & medicinal chemistry.

N-Methylbenzanilide derivatives as a novel class of selective V(1A) receptor antagonists.

J. Tsukada, S. Tsukamoto, A. Kakefuda, 2002, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of phenoxypyridine derivatives as novel inhibitors of the sodium-calcium exchanger.

Hiroyoshi Yamada, S. Sakamoto, A. Kakefuda, 2004, Bioorganic & medicinal chemistry.

Anti-herpes Activities of Isonucleoside Analogues with Variable Bases at the 2′ Position

S. Shuto, A. Matsuda, M. Baba, 1995 .

Discovery of 2-methyl-1-{1-[(5-methyl-1H-indol-2-yl)carbonyl]piperidin-4-yl}propan-2-ol: a novel, potent and selective type 5 17β-hydroxysteroid dehydrogenase inhibitor.

Kazushi Watanabe, Aya Kikuchi, M. Okada, 2013, Bioorganic & medicinal chemistry.

Synthesis and pharmacological evaluation of 2-(3-piperidyl)-1,2,3,4-tetrahydroisoquinoline derivatives as specific bradycardic agents.

Toshihiro Watanabe, N. Masuda, A. Kakefuda, 2003, Chemical & pharmaceutical bulletin.

Nucleosides and nucleotides. 147. Synthesis of DNA dodecamers containing oxetanocin A and (2R, 3R)-2-C-(adenin-9-yl)-1,4-anhydro-2,3-dideoxy-3-C-hydroxymethyl-D-arabitol☆

A. Matsuda, A. Ono, A. Kakefuda, 1996 .

Nucleosides and Nucleotides. 104. Radical and Palladium-Catalyzed Deoxygenation of the Allylic Alcohol Systems in the Sugar Moiety of Pyrimidine Nucleosides§,1

A. Matsuda, A. Kakefuda, Y. Yoshimura, 1992 .

Nucleosides and nucleotides. 132. Synthesis and biological evaluations of ring-expanded oxetanocin analogues: Purine and pyrimidine analogues of 1,4-anhydro-2-deoxy-d-arabitol and 1,4-anhydro-2-deoxy-3-hydroxymethyl-d-arabitol

S. Shuto, A. Matsuda, Takuma Sasaki, 1994 .

Synthesis and pharmacological evaluation of N-acyl-1,2,3,4-tetrahydroisoquinoline derivatives as novel specific bradycardic agents.

Toshihiro Watanabe, N. Masuda, S. Tsukamoto, 2004, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of phenylacetyl derivatives having low central nervous system permeability as potent and selective M2 muscarinic receptor antagonists.

A. Kakefuda, A. Tanaka, H. Shibata, 1998, Chemical & pharmaceutical bulletin.

Synthesis of novel succinamide derivatives having the 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one skeleton as potent and selective M2 muscarinic receptor antagonists. I.

A. Kakefuda, H. Shibata, T. Watanabe, 1997, Chemical & pharmaceutical bulletin.

Synthesis and pharmacological evaluation of piperidinoalkanoyl-1,2,3,4-tetrahydroisoquinoline derivatives as novel specific bradycardic agents.

Toshihiro Watanabe, N. Masuda, S. Tsukamoto, 2004, Bioorganic & medicinal chemistry letters.

AN EFFICIENT SYNTHESIS OF (±)-6,7-DIMETHOXY-1-OXO-2-(3-PIPERIDYL)-1,2,3,4-TETRAHYDROISOQUINOLINE

Toshihiro Watanabe, S. Tsukamoto, S. Sakamoto, 2001 .

(+/-)-2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinolines as a new class of specific bradycardic agents.

Toshihiro Watanabe, N. Masuda, S. Tsukamoto, 2003, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of 6-{4-[(3-fluorobenzyl)oxy]phenoxy}nicotinamide derivatives as a novel class of NCX inhibitors: a QSAR study.

S. Sakamoto, A. Kakefuda, Ippei Sato, 2005, Bioorganic & medicinal chemistry.

Synthesis and biological activity of novel 4,4-difluorobenzazepine derivatives as non-peptide antagonists of the arginine vasopressin V1A receptor.

M. Orita, J. Tsukada, A. Kakefuda, 2006, Bioorganic & medicinal chemistry.