P. Shah

发表

The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate.

G. Hardy, T. Skarzynski, O. Singh, 2001, Bioorganic & medicinal chemistry letters.

Discovery of potent inhibitors of the lysophospholipase autotaxin.

H. Ovaa, A. Turnbull, W. Moolenaar, 2016, Bioorganic & medicinal chemistry letters.

Utilizing the Asymmetric Amino-Cope Rearrangement as a Novel Approach to Enantiomerically Enriched 3-Substituted Aldehydes

M. Essat, S. M. Allin, P. Shah, 2010 .

Applications of the amino-Cope rearrangement: synthesis of tetrahydropyran, delta-lactone and piperidine targets.

D. M. Andrews, V. McKee, M. Edgar, 2005, Organic and biomolecular chemistry.

Preparation and Diels–Alder reactivity of thieno[2,3-c]-and thieno[3,2-c]-pyran-3-ones. Stable 2,3-dimethylenethiophene derivatives; synthesis of benzothiophenes

C. Moody, P. Shah, P. Jackson, 1990 .

Diels-Alder reactivity of pyrano[3,4-b]indol-3-ones. Part 3. Intramolecular Diels-Alder reactions

C. Moody, P. Shah, P. Knowles, 1988 .

Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams.

G. Hardy, D. Belton, T. Skarzynski, 2001, Bioorganic & medicinal chemistry letters.

Diels-Alder reactivity of pyrano[3,4-b]indol-3-ones. Part 4. Synthesis of the carbazole alkaloids carbazomycin A and B and hyellazole

C. Moody, P. Shah, 1989 .

Synthesis of the carbazole alkaloids carbazomycin A and B and hyellazole

C. Moody, P. Shah, 1989 .

A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure trans-5-Oxohexahydropyrrolo[3,2-b]pyrroles (Pyrrolidine-trans-lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium Methodology.

Martin R. Johnson, S. Hodgson, S. Walls, 1999, The Journal of organic chemistry.

Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate.

David Haigh, Malcolm Ellis, George Burton, 2007, Journal of medicinal chemistry.

1,4-dihydropyrano[3,4-b]indol-3-ones as Precursors to indole-2,3-quinodimethanes

C. Moody, P. Shah, E. Fray, 1993 .

Pyrano[3,4-b]thiophen-5-ones, stable thiophene-2,3-quinodimethaneequivalents

C. Moody, P. Shah, P. Jackson, 1988 .

Diels–Alder reactivity of pyrano[3,4-b]indol-3-ones. Part 2. Steric and electronic effects in the addition to alkynes

C. Moody, P. Shah, 1988 .

Diels-Alder Reactivity of Pyrano(3,4-b)indol-3-ones. Part 2. Steric and Electronic Effects in the Addition to Alkynes.

C. Moody, P. Shah, 1988 .

Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151).

Martin R. Johnson, G. Hardy, A. Wonacott, 2002, Journal of medicinal chemistry.