C. Molloy

The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate.

G. Hardy, T. Skarzynski, O. Singh, 2001, Bioorganic & medicinal chemistry letters.

Oxidative neuropathology and putative chemical entities for alzheimer’s disease: Neuroprotective effects of salen-manganese catalytic anti-oxidants

J. Barnes, P. Soden, S. Doctrow, 2009, Neurotoxicity Research.

6,6'-Bis(2-hydroxyphenyl)-2,2'-bipyridine manganese(III) complexes: a novel series of superoxide dismutase and catalase mimetics.

G. Tranter, A. Walker, S. Doctrow, 2001, Bioorganic & medicinal chemistry letters.

Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams.

G. Hardy, D. Belton, T. Skarzynski, 2001, Bioorganic & medicinal chemistry letters.

A microplate assay measuring chloride ion channel activity.

C. Molloy, M. West, Christopher Molloy, 1996, Analytical biochemistry.

Syntheses of trans-5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles and trans-5-oxo-hexahydro-furo[3,2-b]pyrroles (pyrrolidine trans-lactams and trans-lactones): new pharmacophores for elastase inhibition.

D. M. Buckley, D. Belton, R. Upton, 1998, Journal of Medicinal Chemistry.

Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151).

Martin R. Johnson, G. Hardy, A. Wonacott, 2002, Journal of medicinal chemistry.