B. Denker

发表

Zonula Occludens-1 Is a Scaffolding Protein for Signaling Molecules

T. Meyer, C. Schwesinger, B. Denker, 2002, The Journal of Biological Chemistry.

Regulation of integrin expression by Gα12

M. Tran, B. Denker, Tianqing Kong, 2010, Cell adhesion & migration.

G alpha 12 inhibits alpha2 beta1 integrin-mediated Madin-Darby canine kidney cell attachment and migration on collagen-I and blocks tubulogenesis.

J. Shah, A. Takakura, Jing Zhou, 2009, Molecular biology of the cell.

Physician and patient tools to improve chronic kidney disease care.

D. Bates, E. Orav, T. Sequist, 2018, The American journal of managed care.

Polycystin-1L2 is a novel G-protein-binding protein.

A. Takakura, Jing Zhou, B. Denker, 2004, Genomics.

Molecular structure and assembly of the tight junction.

S. Nigam, B. Denker, 1998, American journal of physiology. Renal physiology.

Low Nephron Number: Initial "Hit" in Adult Hypertension and Renal Disease

B. Brenner, G. Curhan, J. Bonventre, 2004 .

Reassembly of the Tight Junction after Oxidative Stress Depends on Tyrosine Kinase Activity*

S. Nigam, T. Meyer, C. Schwesinger, 2001, The Journal of Biological Chemistry.

Autosomal Recessive Alport Syndrome Unveiled by Pregnancy

I. Stillman, M. Pollak, B. Denker, 2019, Nephron.

Primary Care Management of Chronic Kidney Disease

David W. Bates, E. John Orav, Thomas D. Sequist, 2011, Journal of General Internal Medicine.

Attaining Renoprotection by Targeting the Renin-Angiotensin System

B. Brenner, G. Curhan, J. Bonventre, 2003 .

Peritoneal Dialysis First: PD Should Be Considered for Dialysis Initiation

J. Tucker, B. Denker, 2009 .

Functional genetic variation in aminopeptidase A (ENPEP): lack of clear association with focal and segmental glomerulosclerosis (FSGS).

G. Appel, S. Tonna, Kang Zhang, 2008, Gene.

Degradation of Heterotrimeric Gαo Subunits via the Proteosome Pathway Is Induced by the hsp90-specific Compound Geldanamycin*

L. Busconi, B. Denker, J. Guan, 2000, The Journal of Biological Chemistry.

Gα12 regulates protein interactions within the MDCK cell tight junction and inhibits tight-junction assembly

J. Shah, A. Yu, N. Grammatikakis, 2008, Journal of Cell Science.

Interaction of heterotrimeric G protein Galphao with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor.

Y. Luo, B. Denker, 1999, The Journal of biological chemistry.

Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.

K. Kosik, B. Denker, Vijay Yanamadala, 2004, The Journal of biological chemistry.

Gα12 Stimulates Apoptosis in Epithelial Cells through JNK1-mediated Bcl-2 Degradation and Up-regulation of IκBα*

L. Gunaratnam, B. Denker, Tianqing Kong, 2007, Journal of Biological Chemistry.

Gα12 Directly Interacts with PP2A

K. Kosik, B. Denker, Vijay Yanamadala, 2004, Journal of Biological Chemistry.

Purkinje cell protein-2 (Pcp2) stimulates differentiation in PC12 cells by Gβγ-mediated activation of Ras and p38 MAPK

Yuan Luo, J. Guan, B. Denker, 2005 .

Purkinje cell protein-2 (Pcp2) stimulates differentiation in PC12 cells by Gbetagamma-mediated activation of Ras and p38 MAPK.

Yuan Luo, B. Denker, J. Guan, 2005, The Biochemical journal.

G (cid:1) 12 Inhibits (cid:1) 2 (cid:2) 1 Integrin–mediated Madin-Darby Canine Kidney Cell Attachment and Migration on Collagen-I and Blocks Tubulogenesis

J. Shah, A. Takakura, J. Kreidberg, 2009 .

Renal Pathophysiology: The Essentials

H. Rennke, B. Denker, 1994 .

Gα12 Regulates Interleukin-8 Expression after Epithelial Cell Injury

Wanfeng Yu, B. Denker, Tianqing Kong, 2016 .

Molecular structure and assembly of the tight junction.

S. Nigam, B. Denker, 1998, The American journal of physiology.

Heterotrimeric Gα12/13 Proteins in Kidney Injury and Disease.

L. Gunaratnam, E. Tutunea-Fatan, B. Denker, 2020, American journal of physiology. Renal physiology.

The biology of epithelial cell tight junctions in the kidney.

E. Sabath, B. Denker, 2011, Journal of the American Society of Nephrology : JASN.

Involvement of Gαi2 in the Maintenance and Biogenesis of Epithelial Cell Tight Junctions*

S. Nigam, B. Denker, S. Nigam, 1998, The Journal of Biological Chemistry.

Kidney injury molecule-1 protects against Gα12 activation and tissue damage in renal ischemia-reperfusion injury.

L. Gunaratnam, R. Suri, A. Şener, 2015, The American journal of pathology.

Gα12 regulates epithelial cell junctions through Src tyrosine kinases

T. Meyer, C. Schwesinger, B. Denker, 2003 .

Expanding role of G proteins in tight junction regulation: Galpha(s) stimulates TJ assembly.

S. Nigam, B. Denker, C. Saha, 2001, Biochemical and Biophysical Research Communications - BBRC.

Involvement of a Heterotrimeric G Protein α Subunit in Tight Junction Biogenesis*

S. Nigam, B. Denker, S. Khawaja, 1996, The Journal of Biological Chemistry.

Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1

R. Flaumenhaft, J. Dilks, A. Kuliopulos, 2011, Proceedings of the National Academy of Sciences.

Inpatient Management of Hyperkalemia

B. Denker, Erika R. Drury, 2020 .

Recent advances in diagnosis and treatment of acute kidney injury in patients with cancer.

E. Sabath, M. L. Robles-Osorio, B. Denker, 2011, European journal of internal medicine.

Analysis of G-protein alpha and beta gamma subunits by in vitro translation.

E. Neer, C. J. Schmidt, B. Denker, 1994, Methods in enzymology.

Clinical and Pathological Heterogeneity in FSGS due to INF2 Mutations

H. Rennke, M. Pollak, Andrea U. Knob, 2022, Kidney international reports.

Association and colocalization of G protein α subunits and Purkinje cell protein 2 (Pcp2) in mammalian cerebellum

J. Oberdick, Yuan Luo, K. Redd, 2002, Journal of neuroscience research.

Disease-associated mutant α-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity

J. Hartwig, T. Stossel, F. Nakamura, 2007, Proceedings of the National Academy of Sciences.

Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules.

P. Agre, F. Kuhajda, B. Smith, 1988, The Journal of biological chemistry.

Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis.

S. Nigam, B. Denker, S. Khawaja, 1996, The Journal of biological chemistry.

Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a calcium switch model of junction formation.

M. Pollak, B. Denker, Jennifer Hunt, 2005, Journal of the American Society of Nephrology : JASN.

α-Actinin-4-Mediated FSGS: An Inherited Kidney Disease Caused by an Aggregated and Rapidly Degraded Cytoskeletal Protein

P. G. Allen, J. Henderson, M. Pollak, 2004, PLoS biology.

NEPHROLOGY Rounds AS PRESENTED IN THE ROUNDS OF

B. Brenner, G. Curhan, J. Bonventre, 2004 .

Domains Necessary for Gα12 Binding and Stimulation of Protein Phosphatase-2A (PP2A): Is Gα12 a Novel Regulatory Subunit of PP2A?

R. Ruediger, B. Denker, T. Meigs, 2007, Molecular Pharmacology.

Polycystin-1 Protein Level Determines Activity of the Gα12/JNK Apoptosis Pathway*

Wanfeng Yu, B. Denker, Tianqing Kong, 2010, The Journal of Biological Chemistry.

Gα12 Activation in Podocytes Leads to Cumulative Changes in Glomerular Collagen Expression, Proteinuria and Glomerulosclerosis

J. Henderson, M. Pollak, Wanfeng Yu, 2011, Laboratory Investigation.

Isolation of proteins related to the Rh polypeptides from nonhuman erythrocytes.

P. Agre, A. Saboori, B. Denker, 1989, The Journal of clinical investigation.

Podocytic Infolding Glomerulopathy in a Patient with Phospholipase A2 Receptor-Positive Membranous Nephropathy and Review of the Literature

H. Rennke, B. Denker, A. Pandit, 2021, Nephron.

Drug-Induced Thrombotic Microangiopathy Resulting in ESRD

Yael K. Heher, B. Denker, K. Agarwal, 2020, Kidney international reports.

Heterotrimeric G proteins and apoptosis: intersecting signaling pathways leading to context dependent phenotypes.

B. Denker, Vijay Yanamadala, Hideyuki Negoro, 2009, Current molecular medicine.

Developmental Upregulation of an Alternative Form of pcp2 with Reduced GDI Activity

M. Meyer, A. Fertala, M. Lauth, 2013, The Cerebellum.

Go associates with another 40 kDa brain protein

B. Denker, Eva J. Neer, 1991, FEBS letters.

Renal Dysfunction Associated with Herbal Remedies and Dietary Supplements

B. Brenner, G. Curhan, J. Bonventre, 2003 .

Cell-Cell Interactions in the Kidney: Inducible Expression of Mutant G Protein α-Subunits in Madin-Darby Canine Kidney Cells for Studies of Epithelial Cell Junction Structure and Function

E. Sabath, B. Denker, 2006 .

Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.

J. Bonventre, T. Lu, Lai Ding, 2015, Physiological Genomics.

Interactions between the amino- and carboxyl-terminal regions of G alpha subunits: analysis of mutated G alpha o/G alpha i2 chimeras.

E. Neer, B. Denker, P. Boutin, 1995, Biochemistry.

Promotion of the GTP-liganded state of the Go alpha protein by deletion of the C terminus.

E. Neer, C. J. Schmidt, B. Denker, 1992, The Journal of biological chemistry.

Galpha12 regulates epithelial cell junctions through Src tyrosine kinases.

T. Meyer, C. Schwesinger, B. Denker, 2003, American journal of physiology. Cell physiology.

Home Blood-Pressure Monitoring: Effective, Well Accepted, Low Cost

B. Denker, J. Wolfrum, 2010 .

H2O2 activates G protein, α 12 to disrupt the junctional complex and enhance ischemia reperfusion injury

Wanfeng Yu, B. Denker, Tianqing Kong, 2012, Proceedings of the National Academy of Sciences.

Mutagenesis of the amino terminus of the alpha subunit of the G protein Go. In vitro characterization of alpha o beta gamma interactions.

E. Neer, C. J. Schmidt, B. Denker, 1992, The Journal of biological chemistry.

Gα12 is required for renal cystogenesis induced by Pkd1 inactivation

J. Bonventre, Jing Zhou, T. Lu, 2016, Journal of Cell Science.

Therapeutic plasma exchange (plasmapheresis)

E. Sabath, B. Denker, 2019, Nephrology Secrets.

Domains Necessary for G (cid:1) 12 Binding and Stimulation of Protein Phosphatase-2A (PP2A): Is G (cid:1) 12 a Novel Regulatory Subunit of PP2A?

R. Ruediger, B. Denker, T. Meigs, 2007 .

Interaction of Heterotrimeric G Protein Gαowith Purkinje Cell Protein-2

B. Denker, Yuan Luo, 1999, Journal of Biological Chemistry.

Analysis of the N-terminal binding domain of Go alpha.

L. Busconi, B. Denker, Liliana Busconi, 1997, The Biochemical journal.

Identification of polycystin-1 and Gα12 binding regions necessary for regulation of apoptosis.

Jing Zhou, Wanfeng Yu, X. Su, 2011, Cellular signalling.

Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.

J. Bonventre, T. Lu, Lai Ding, 2015, Physiological genomics.