J. Castro‐Pichel

发表

New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold.

David Barros, L. Ballell-Pages, C. Chung, 2016, European journal of medicinal chemistry.

4‐Substituted Thioquinolines and Thiazoloquinolines: Potent, Selective, and Tween‐80 in vitro Dependent Families of Antitubercular Agents with Moderate in vivo Activity

David Barros, Lluís Ballell, Jaime. Escribano, 2011, ChemMedChem.

Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery

John P. Overington, James R. Brown, Robert H Bates, 2015, PloS one.

A facile synthesis of ascamycin and related analogues

M. García-López, F. Heras, J. Castro‐Pichel, 1987 .

An improved one-pot method for the stereoselective synthesis of the (2S,3R)-3-amino-2-hydroxy acids: key intermediates for bestatin and amastatin

M. García-López, R. Herranz, J. Castro‐Pichel, 1990 .

Aminodeoxybestatin and epi-aminodeoxybestatin: stereospecific synthesis and aminopeptidase inhibition

M. García-López, C. Pérez, R. Herranz, 1992 .

Stereoselection in the synthesis of threo- and erythro-3-amino-2-hydroxy-4-phenyl-butanoic acid using chiral acetal templates

M. García-López, R. Herranz, J. Castro‐Pichel, 1989 .

Tributyltin Cyanide, a Novel Reagent for the Stereoselective Preparation of 3-Amino-2-hydroxy Acids via Cyanohydrin Intermediates

R. Herranz, J. Castro‐Pichel, T. Garcia‐Lopez, 1989 .

5′-O-[N-(Amnoacyl)Sulfamoyl]Nucleosides. Synthesis and Antiviral and Cytostatic Activities

M. García-López, C. Pérez, R. Herranz, 1990 .

Ketomethylenebestatin: Synthesis and Aminopeptidase Inhibition

I. Gomez-Monterrey, M. García-López, C. Pérez, 1993, Archiv der Pharmazie.

Synthesis of penicillamine- and cysteine-containing nucleoamino acids as potential antivirals and aminopeptidase B inhibitors

M. García-López, J. Balzarini, E. Clercq, 1991 .

Synthesis of ketomethylene-bestatin

I. Gomez-Monterrey, M. García-López, C. Pérez, 1991 .

An Improved One-Pot Method for the Stereoselective Synthesis of the (2S,3R)-3-Amino-2-hydroxy Acids: Key Intermediates for Bestatin and Amastatin.

M. García-López, R. Herranz, J. Castro‐Pichel, 1990 .

Synthesis of 5′‐N‐(α‐Amino‐β‐mercaptoacyl)amino‐5′‐deoxynucleosides as potential antiviral compounds

E. De Clercq, M. García-López, J. Balzarini, 1991 .

Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA.

Hongfang Yang, William McDowell, Paolo A Centrella, 2014, Journal of medicinal chemistry.

Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor

J. Sacchettini, E. Alvarez, J. Lavandera, 2016, EBioMedicine.

Cyclopropyl Carboxamides: A New Oral Antimalarial Series Derived from the Tres Cantos Anti-Malarial Set (TCAMS).

Simon J F Macdonald, F. Gamo, Laura M Sanz, 2011, ACS medicinal chemistry letters.

N‐Benzyl‐4‐((heteroaryl)methyl)benzamides: A New Class of Direct NADH‐Dependent 2‐trans Enoyl–Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity

J. Sacchettini, M. Convery, Delia Blanco, 2016, ChemMedChem.