M. Ipek

发表

Identification and SAR of a new series of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitors.

Y. Ni, R. Denny, J. Telliez, 2011, Bioorganic & medicinal chemistry letters.

Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model.

K. Svenson, J. Bard, T. Mansour, 2009, Journal of medicinal chemistry.

Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.

J. D. Clark, M. Hegen, J. McKew, 2008, Journal of medicinal chemistry.

Discovery of indazoles as inhibitors of Tpl2 kinase.

David R. Anderson, Y. Ni, R. Denny, 2011, Bioorganic & medicinal chemistry letters.

Discovery of HSD-621 as a Potential Agent for the Treatment of Type 2 Diabetes.

K. Svenson, J. Bard, T. Mansour, 2013, ACS medicinal chemistry letters.

Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: a class of potent aggrecanase-1 inhibitors.

J. Skotnicki, E. Feyfant, J. Xiang, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors.

T. Rush, J. Xiang, S. Tam, 2006, Bioorganic & medicinal chemistry letters.

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.

T. Rush, J. Skotnicki, J. Levin, 2005, Bioorganic & medicinal chemistry.

Copper(II) Complexes of Bis(1,4,7-triazacyclononane) Ligands with Polymethylene Bridging Groups: An Equilibrium and Structural Study.

M. Ipek, L. J. Zompa, B. Dasgupta, 1997, Inorganic chemistry.

β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action

J. McKew, T. Mansour, J. Xiang, 2007 .

Synthesis and biological evaluation of sulfonamidooxazoles and β-keto sulfones: selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

J. Xiang, M. Tam, J. Tobin, 2005 .

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.

J. McKew, T. Mansour, J. Xiang, 2008, Journal of medicinal chemistry.

beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action.

J. McKew, T. Mansour, J. Xiang, 2007, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of sulfonamidooxazoles and beta-keto sulfones: selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.

J. Xiang, M. Tam, J. Tobin, 2005, Bioorganic & Medicinal Chemistry Letters.

Structure‐Based Optimization of Protein Tyrosine Phosphatase‐1 B Inhibitors: Capturing Interactions with Arginine 24

Wei Li, A. Moretto, D. Joseph-McCarthy, 2008, ChemMedChem.

Continued exploration of biphenylsulfonamide scaffold as a platform for aggrecanase-1 inhibition.

J. Xiang, L. Xing, S. Tam, 2011, Bioorganic & medicinal chemistry letters.