Y. Segall

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The role of AChE active site gorge in determining stereoselectivity of charged and noncharged VX enantiomers.

A. Shafferman, Y. Karton, B. Velan, 2005, Chemico-biological interactions.

Diethyl bromodifluoromethylphosphonate: a highly efficient and environmentally benign difluorocarbene precursor

G. Sod-Moriah, Y. Segall, Y. Zafrani, 2009 .

Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket.

N. Ariel, A. Shafferman, S. Cohen, 1993, The Journal of biological chemistry.

3-Substituted 2-halopropenals: mutagenicity, detoxification and formation from 3-substituted 2,3-dihalopropanal promutagens.

J. Casida, D. Dohn, Y. Segall, 1985, Mutation research.

Carbocation-Mediated Processes in Biocatalysts. Contribution of Aromatic Moieties

A. Shafferman, B. Velan, H. Benschop, 1997 .

Major intermediates in organophosphate synthesis (PCl3, POCl3, PSCl3, and their diethyl esters) are anticholinesterase agents directly or on activation.

J. Casida, G. B. Quistad, S. Sparks, 2003, Chemical research in toxicology.

Direct determination of the chemical composition of acetylcholinesterase phosphonylation products utilizing electrospray‐ionization mass spectrometry

A. Shafferman, B. Velan, R. Barak, 1997, FEBS letters.

Organophosphoro(thioperoxoic) acids: Direct observation and reactivity

J. Casida, R. Toia, Y. Segall, 1990 .

Molecular Aspects of Catalysis and of Allosteric Regulation of Aceytlcholinesterases

N. Ariel, S. Reuveny, A. Shafferman, 1995 .

α-AMINO ACID DERIVED BISPHOSPHONATES. SYNTHESIS AND ANTI-RESORFTIVE ACTIVITY

D. Mizrahi, Y. Segall, T. Waner, 2001 .

Studies of the Synthesis of Diethyl Cyclopropylphosphonate and Its Thio and Seleno Analogs

Y. Segall, Y. Zafrani, Ravit Chen, 2008 .

Chemical consequences of hydride addition to aromatic olefins

H. Leader, Y. Segall, I. Granoth, 1976 .

Resolving pathways of interaction of covalent inhibitors with the active site of acetylcholinesterases: MALDI-TOF/MS analysis of various nerve agent phosphyl adducts.

A. Shafferman, E. Elhanany, B. Velan, 2001, Chemical research in toxicology.

Evidence for P-N bond scission in phosphoroamidate nerve agent adducts of human acetylcholinesterase.

A. Shafferman, B. Velan, R. Barak, 2000, Biochemistry.

Exploring the active center of human acetylcholinesterase with stereomers of an organophosphorus inhibitor with two chiral centers.

N. Ariel, A. Shafferman, B. Velan, 1999, Biochemistry.

Oxidative conversion of phosphorothiolates to phosphinyloxysulfonates probably via phosphorothiolate s-oxides

J. Casida, Y. Segall, 1982 .

SYNTHESIS, REACTIVITY AND CONFORMATION OF 10,11-DIHYDRODIBENZO-[b,f]PHOSPHEPIN AND DIBENZO[b,f]PHOSPHEPIN DERIVATIVES. PHOSPHORUS ANALOGUES OF IMINOBIBENZYL ANTIDEPRESSANTS

Y. Segall, I. Granoth, E. Shirin, 1980 .

Nucleophilic transformations of cyclic phosphate triesters

Y. Karton, Y. Segall, N. Ashkenazi, 2004 .

Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors.

J. Casida, D. Nomura, G. B. Quistad, 2003, Bioorganic & medicinal chemistry letters.

Preparation of a dibenzo[b,e]phosphorin. Selective phosphine oxide reduction by trichlorosilane

A. Kalir, Y. Segall, I. Granoth, 1974 .

Functional Characteristics of the Oxyanion Hole in Human Acetylcholinesterase*

B Velan, N. Ariel, A. Shafferman, 1998, The Journal of Biological Chemistry.

Stereoselectivity toward VX is determined by interactions with residues of the acyl pocket as well as of the peripheral anionic site of AChE.

A. Shafferman, Y. Karton, B. Velan, 2004, Biochemistry.

The Architecture of Human Acetylcholinesterase Active Center Probed by Interactions with Selected Organophosphate Inhibitors

B Velan, N. Ariel, A. Shafferman, 1996, The Journal of Biological Chemistry.

Mutagenic potency of haloacroleins and related compounds.

J. Casida, J. Rosen, Y. Segall, 1980, Mutation research.

Toxicological Significance of Oxidation and Rearrangement Reactions ofS-Chloroallyl Thio- and Dithiocarbamate Herbicides

J. Casida, I. Schuphan, J. Rosen, 1981 .

Biomimetic chemistry as a useful tool for studying reactive metabolites of pesticides.

Y. Segall, 2011, Journal of agricultural and food chemistry.

Contribution of Aromatic Moieties of Tyrosine 133 and of the Anionic Subsite Tryptophan 86 to Catalytic Efficiency and Allosteric Modulation of Acetylcholinesterase (*)

N. Ariel, A. Shafferman, B. Velan, 1995, The Journal of Biological Chemistry.

Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides.

J. Casida, D. Nomura, Daniel K. Nomura, 2002, Toxicology letters.

Crystal Structures of “Aged” Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase

J. Sussman, I. Silman, M. Harel, 1998 .

Direct observation and elucidation of the structures of aged and nonaged phosphorylated cholinesterases by 31P NMR spectroscopy.

N. Ariel, Y. Ashani, B. P. Doctor, 1993, Biochemistry.

Toxicological and structural features of organophosphorus and organosulfur cannabinoid CB1 receptor ligands.

J. Casida, D. Nomura, Daniel K. Nomura, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Cannabinoid CB1 Receptor Chemical Affinity Probes: Methods Suitable for Preparation of Isopropyl [11,12-3H]Dodecylfluorophosphonate and [11,12-3H]Dodecanesulfonyl Fluoride

J. Casida, G. B. Quistad, Y. Segall, 2003 .

Selective inhibitors of fatty acid amide hydrolase relative to neuropathy target esterase and acetylcholinesterase: toxicological implications.

J. Casida, D. Nomura, Daniel K. Nomura, 2002, Toxicology and applied pharmacology.

Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level.

J. Sussman, I. Silman, M. Harel, 1999, Biochemistry.

Prophylaxis against organophosphate poisoning by an enzyme hydrolysing organophosphorus compounds in mice.

Y. Ashani, N. Rothschild, L. Raveh, 1991, Life sciences.

Conformational differences between aged and nonaged pyrenebutyl-containing organophosphoryl conjugates of chymotrypsin as detected by optical spectroscopy.

Y. Ashani, I. Silman, J. Grunwald, 1989, Biochemistry.

Aged and non-aged pyrenebutyl-containing organophosphoryl conjugates of chymotrypsin. Preparation and comparison by 31P-NMR spectroscopy.

Y. Ashani, I. Silman, J. Grunwald, 1989, Biochemical pharmacology.

COMPOSITION OF TECHNICAL ETHEPHON (2-CHLOROETHYL)PHOSPHONIC ACID AND SOME ANALOGUES RELATIVE TO THEIR REACTIVITY AND BIOLOGICAL ACTIVITY

J. Casida, R. L. Grendell, R. Toia, 1991 .

Diethyl Bromodifluoromethylphosphonate: A Highly Efficient and Environmentally Benign Difluorocarbene Precursor.

G. Sod-Moriah, Y. Segall, Y. Zafrani, 2009 .

The mechanism of nucleophilic displacements at phosphorus in chloro-substituted methylphosphonate esters: P-O vs P-C bond cleavage: a DFT study.

G. Sod-Moriah, Y. Segall, Ravit Chen, 2010, The Journal of organic chemistry.

Selective site controlled nucleophilic attacks in 5-membered ring phosphate esters: unusual C-O vs. common P-O bond cleavage.

Y. Karton, M. Bendikov, Sanjio S. Zade, 2005, Chemical communications.

Function-specific blockage of M1 and M3 muscarinic acetylcholine receptors by VX and echothiophate

D. Barak, Z. Pittel, Y. Segall, 2006, Brain Research.

Protection against tabun toxicity in mice by prophylaxis with an enzyme hydrolyzing organophosphate esters.

Y. Ashani, N. Rothschild, Y. Henis, 1992, Biochemical pharmacology.