Lydiane Funkelstein

发表

Proteomics of dense core secretory vesicles reveal distinct protein categories for secretion of neuroeffectors for cell-cell communication.

D. O'Connor, C. Sigurdson, A. L. La Spada, 2010, Journal of proteome research.

Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters

C. Peters, T. Reinheckel, Lydiane Funkelstein, 2012, Journal of neurochemistry.

Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: Protease gene knockout and inhibitor studies

C. Peters, T. Reinheckel, T. Foulon, 2009, Peptides.

The novel role of cathepsin L for neuropeptide production illustrated by research strategies in chemical biology with protease gene knockout and expression.

Lydiane Funkelstein, V. Hook, 2011, Methods in molecular biology.

Cathepsin L participates in dynorphin production in brain cortex, illustrated by protease gene knockout and expression

C. Peters, Shin‐Rong Hwang, A. Minokadeh, 2010, Molecular and Cellular Neuroscience.

Human Cathepsin V Protease Participates in Production of Enkephalin and NPY Neuropeptide Neurotransmitters*

D. O'Connor, C. Peters, T. Reinheckel, 2012, The Journal of Biological Chemistry.

Major Role of Cathepsin L for Producing the Peptide Hormones ACTH, β-Endorphin, and α-MSH, Illustrated by Protease Gene Knockout and Expression*

C. Peters, T. Reinheckel, F. Beuschlein, 2008, Journal of Biological Chemistry.

Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides

Vivian Hook, M. Beinfeld, J. Zadina, 2010, Neuropeptides.

Human pituitary contains dual cathepsin L and prohormone convertase processing pathway components involved in converting POMC into the peptide hormones ACTH, α-MSH, and β-endorphin

Shin‐Rong Hwang, Charles Mosier, Lydiane Funkelstein, 2009, Endocrine.

Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression

C. Peters, T. Reinheckel, Shin‐Rong Hwang, 2008, Journal of neurochemistry.

Redundant functions but temporal and regional regulation of two alternatively spliced isoforms of Semaphorin 3F in the nervous system

G. Rougon, H. Drabkin, V. Castellani, 2003, Molecular and Cellular Neuroscience.

Proteases for processing proneuropeptides into peptide neurotransmitters and hormones.

Jill L. Wegrzyn, S. Bark, J. Wegrzyn, 2008, Annual review of pharmacology and toxicology.

Spinal astrocytes produce and secrete dynorphin neuropeptides

B. Fitzsimmons, T. Yaksh, Lydiane Funkelstein, 2013, Neuropeptides.

Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease.

M. Kindy, S. Bark, J. Wegrzyn, 2012, Biochimica et biophysica acta.

Pyroglutamate-Amyloid-β and Glutaminyl Cyclase Are Colocalized with Amyloid-β in Secretory Vesicles and Undergo Activity-Dependent, Regulated Secretion

B. Koch, H. Demuth, H. Cynis, 2014, Neurodegenerative Diseases.

A semaphorin code defines subpopulations of spinal motor neurons during mouse development

J. Livet, C. Henderson, G. Rougon, 2005, The European journal of neuroscience.

Human iPSC Neurons Display Activity-Dependent Neurotransmitter Secretion: Aberrant Catecholamine Levels in Schizophrenia Neurons

F. Gage, YongSung Kim, K. Brennand, 2014, Stem cell reports.

Neuropeptidomic Components Generated by Proteomic Functions in Secretory Vesicles for Cell–Cell Communication

Nuno Bandeira, Nitin Gupta, Steven Bark, 2010, The AAPS Journal.

Beta-amyloid peptides undergo regulated co-secretion with neuropeptide and catecholamine neurotransmitters

Vivian Hook, Charles Mosier, Charles Mosier, 2013, Peptides.

Proteases for processing proneuropeptides into peptide neurotransmitters and hormones.

S. Bark, J. Wegrzyn, Shin‐Rong Hwang, 2008, Annual review of pharmacology and toxicology.