J. Fung-Tomc

发表

Correlation between Genotype and Phenotypic Categorization of Staphylococci Based on Methicillin Susceptibility and Resistance

L. Valera, E. Gradelski, Lauren Aleksunes, 2001, Journal of Clinical Microbiology.

Emergence of homogeneously methicillin-resistant Staphylococcus aureus

R. Kessler, K. Denbleyker, E. Gradelski, 1991, Journal of clinical microbiology.

Bactericidal mechanism of gatifloxacin compared with other quinolones.

E. Gradelski, D. Bonner, J. Fung-Tomc, 2002, The Journal of antimicrobial chemotherapy.

Antibacterial Spectrum of a Novel Des-Fluoro(6) Quinolone, BMS-284756

L. Valera, L. Aleksunes, E. Gradelski, 2000, Antimicrobial Agents and Chemotherapy.

In vitro activity of a novel des-fluoro(6) quinolone, garenoxacin (BMS-284756), against rapidly growing mycobacteria and Nocardia isolates.

L. Valera, H. Yigit, E. Gradelski, 2002, The Journal of antimicrobial chemotherapy.

Patents on β-lactam antibacterials: January 1999 to March 2001

J. Fung-Tomc, O. Kim, 2001 .

Comparison of the inhibitory and bactericidal activity of aztreonam and amikacin against gram negative aerobic bacilli.

W. Lincourt, R. Kessler, J. Fung-Tomc, 1988, Annals of clinical and laboratory science.

In Vitro and In Vivo Activities of a Novel Cephalosporin, BMS-247243, against Organisms other than Staphylococci

Hyekyung Yang, E. Gradelski, D. Bonner, 2002, Antimicrobial Agents and Chemotherapy.

Nocathiacins, new thiazolyl peptide antibiotics from Nocardia sp. I. Taxonomy, fermentation and biological activities.

J. Leet, K. S. Lam, Daniel M. Brown, 2003, The Journal of antibiotics.

Recent developments in pradimicin-benanomicin and triazole antibiotics.

D. Bonner, J. Fung-Tomc, 1997, Expert opinion on investigational drugs.

In vitro antifungal and fungicidal spectra of a new pradimicin derivative, BMS-181184

R. Kessler, D. Bonner, J. Fung-Tomc, 1995, Antimicrobial agents and chemotherapy.

Fluoronaphthyridines as antibacterial agents. 4. Synthesis and structure-activity relationships of 5-substituted-6-fluoro-7-(cycloalkylamino)-1,4-dihydro-4-oxo-1,8- naphthyridine-3-carboxylic acids.

P. D. Di Cesare, R. Kessler, B. Ledoussal, 1992, Journal of medicinal chemistry.

Antibacterial activities of cefprozil compared with those of 13 oral cephems and 3 macrolides

R. Kessler, K. Denbleyker, D. Bonner, 1995, Antimicrobial agents and chemotherapy.

Activity of carbapenem BMS-181139 against Pseudomonas aeruginosa is not dependent on porin protein D2

M. Pucci, R. Kessler, E. Gradelski, 1995, Antimicrobial agents and chemotherapy.

In vitro antifungal activity of BMS-207147 and itraconazole against yeast strains that are non-susceptible to fluconazole.

T. C. White, D. Bonner, J. Fung-Tomc, 1999, Diagnostic microbiology and infectious disease.

Activity of gatifloxacin and ciprofloxacin in combination with other antimicrobial agents.

L. Valera, E. Gradelski, D. Bonner, 2001, International journal of antimicrobial agents.

Correlation of in vitro and in vivo resistance development to antimicrobial agents

J. Fung-Tomc, 1990 .

Antimicrobial Evaluation of Nocathiacins, a Thiazole Peptide Class of Antibiotics

M. Pucci, L. Discotto, J. Barrett, 2004, Antimicrobial Agents and Chemotherapy.

In Vitro Activity of a New Oral Triazole, BMS-207147 (ER-30346)

D. Bonner, J. Fung-Tomc, E. Huczko, 1998, Antimicrobial Agents and Chemotherapy.

Synthesis and antibacterial activity of some novel 6-methyl- and 6-propenyl-substituted carbapenems.

E. Ruediger, M. Menard, J. Fung-Tomc, 1992, Journal of Medicinal Chemistry.

Fluoronaphthyridines and -quinolones as antibacterial agents. 5. Synthesis and antimicrobial activity of chiral 1-tert-butyl-6-fluoro-7-substituted-naphthyridones.

P. D. Di Cesare, R. Kessler, B. Ledoussal, 1992, Journal of medicinal chemistry.

An examination of O-2-isocephems as orally absorbable antibiotics.

R. Kessler, M. Menard, J. Fung-Tomc, 1988, Journal of medicinal chemistry.

In Vitro and In Vivo Activities of a Novel Cephalosporin, BMS-247243, against Methicillin-Resistant and -Susceptible Staphylococci

I. Medina, M. Pucci, Junius Clark, 2002, Antimicrobial Agents and Chemotherapy.

Use of amino acid N-carboxy anhydride in the synthesis of peptide prodrug derivatives (including beta-chloroalanyl) of C4-beta-aminoalkyl carbapenems. In vitro and in vivo activities.

J. Fung-Tomc, J. Desiderio, V. S. Rao, 1993, The Journal of antibiotics.

The synthesis, antibacterial, and beta-lactamase inhibitory activity of a novel asparenomycin analog.

M. Menard, E. Gradelski, J. Fung-Tomc, 1992, The Journal of antibiotics.

In vitro antibacterial spectrum of a new broad-spectrum 8-methoxy fluoroquinolone, gatifloxacin.

D. Bonner, J. Fung-Tomc, E. Huczko, 2000, The Journal of antimicrobial chemotherapy.

Synthesis and anti-MRSA Activity of Novel Cephalosporin Derivatives

R. Perrone, M. Pucci, S. Hoeft, 2000 .

Fluoronaphthyridines and -quinolones as antibacterial agents. 3. Synthesis and structure-activity relationships of new 1-(1,1-dimethyl-2-fluoroethyl), 1-[1-methyl-1-(fluoromethyl)-2-fluoroethyl], and 1-[1,1-(difluoromethyl)-2-fluoroethyl] substituted derivatives.

R. Kessler, B. Ledoussal, J. Fung-Tomc, 1991, Journal of medicinal chemistry.

Antibacterial activity of BMS-180680, a new catechol-containing monobactam

K. Bush, R. Flamm, E. Gradelski, 1997, Antimicrobial agents and chemotherapy.

Ciprofloxacin-induced, low-level resistance to structurally unrelated antibiotics in Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus

D. Bonner, J. Fung-Tomc, B. Kolek, 1993, Antimicrobial Agents and Chemotherapy.

In vitro activity of ravuconazole against Zygomycetes, Scedosporium and Fusarium isolates.

D. Bonner, J. Fung-Tomc, E. Huczko, 2003, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Novel C‐acylated triazole derivatives of ravuconazole, an azole antifungal agent

Stella Huang, J. Bronson, Y. Ueda, 2008 .

In vitro and in vivo evaluations of a new broad-spectrum oral cephalosporin, BMY-28232, and its prodrug esters

H. Kawaguchi, T. Oki, R. Kessler, 1989, Antimicrobial Agents and Chemotherapy.

In vitro activities of cefepime alone and with amikacin against aminoglycoside-resistant gram-negative bacteria

R. Kessler, J. Fung-Tomc, E. Huczko, 1991, Antimicrobial Agents and Chemotherapy.

Synergistic Activities of Gatifloxacin in Combination with Other Antimicrobial Agents against Pseudomonas aeruginosa and Related Species

L. Valera, E. Gradelski, D. Bonner, 2001, Antimicrobial Agents and Chemotherapy.

Detection of microbial antigens in spinal fluid and blood

J. Fung-Tomc, 1986 .

Fourth-generation cephalosporins

J. Fung-Tomc, 1997 .

Differences in the resistant variants of Enterobacter cloacae selected by extended-spectrum cephalosporins

T. Dougherty, R. Kessler, E. Gradelski, 1996, Antimicrobial agents and chemotherapy.

Activity of cefepime against ceftazidime- and cefotaxime-resistant gram-negative bacteria and its relationship to beta-lactamase levels

F. J. DeOrio, T. Dougherty, R. Kessler, 1989, Antimicrobial Agents and Chemotherapy.

Frequency of in vitro resistance of Pseudomonas aeruginosa to cefepime, ceftazidime, and cefotaxime

R. Kessler, J. Fung-Tomc, E. Huczko, 1988, Antimicrobial Agents and Chemotherapy.

Susceptibility of bacterial isolates to gatifloxacin and ciprofloxacin from clinical trials 1997-1998.

L. Valera, D. Bonner, J. Fung-Tomc, 2000, International journal of antimicrobial agents.

Activity of quinolones in the Ames Salmonella TA102 mutagenicity test and other bacterial genotoxicity assays

D. Bonner, J. Fung-Tomc, B. Kolek, 1993, Antimicrobial Agents and Chemotherapy.

Activity of gatifloxacin against strains resistant to ofloxacin and ciprofloxacin and its ability to select for less susceptible bacterial variants.

E. Gradelski, D. Bonner, J. Fung-Tomc, 2001, International journal of antimicrobial agents.

Susceptibility of United States clinical trial isolates to cefprozil and cefaclor.

R. Kessler, J. Fung-Tomc, 1994, Diagnostic microbiology and infectious disease.

In vitro and in vivo antibacterial activities of BMY 40062, a new fluoronaphthyridone

G. Warr, R. Kessler, J. Fung-Tomc, 1989, Antimicrobial Agents and Chemotherapy.

Synthesis and antibacterial activity of dihydro-1,2-oxazine and 2-pyrazoline oxazolidinones: novel analogs of linezolid.

Dennis K. Taylor, J. Bronson, K. Denbleyker, 2005, Bioorganic & medicinal chemistry letters.

Susceptibility of bacterial isolates to beta-lactam antibiotics from U.S. clinical trials over a 5-year period.

R. Kessler, J. Fung-Tomc, 1996, The American journal of medicine.

Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials.

A. Marinier, L. Snyder, J. Barrett, 2004, Bioorganic & Medicinal Chemistry Letters.

Activity of the novel des-fluoro(6) quinolone BMS-284756 against methicillin-susceptible and -resistant staphylococci.

L. Valera, E. Gradelski, D. Bonner, 2001, The Journal of antimicrobial chemotherapy.

THE SYNTHESIS, ANTIBACTERIAL, AND ^-LACTAMASE INHIBITORS ACTIVITY OF A NOVEL ASPARENOMYCIN ANALOG

J. Fung-Tomc, H. Mastalerz, G. Bouthillier, 2006 .

Cyclopentanone ring-cleaved pleuromutilin derivatives.

T. Dougherty, J. Bronson, K. Denbleyker, 2007, European journal of medicinal chemistry.

Intracellular penetration and bactericidal activity of the novel des-fluoro(6) quinolone, BMS-284756.

G. Warr, D. Bonner, J. Fung-Tomc, 2001, The Journal of antimicrobial chemotherapy.

Comparative killing kinetics of the novel des-fluoro(6) quinolone BMS-284756, fluoroquinolones, vancomycin and beta-lactams.

L. Valera, E. Gradelski, D. Bonner, 2001, International journal of antimicrobial agents.

Synthesis and in vitro antibacterial activity of new semi-synthetic noviosylcoumarin antibiotics: chemical modification at the C-3′ ester

Y. Ueda, J. Fung-Tomc, J. Chuang, 1994 .

Comparative Killing Rates of Fluoroquinolones and Cell Wall-Active Agents

L. Valera, E. Gradelski, D. Bonner, 2000, Antimicrobial Agents and Chemotherapy.

Antibacterial Pleuromutilin Derivatives based on Alternate Core Structures:Arigoni and Birch Chemistry Revisited

T. Dougherty, Stella Huang, J. Bronson, 2008 .

Fluoronaphthyridines and -quinolones as Antibacterial Agents. Part 5. Synthesis and Antimicrobial Activity of Chiral 1-tert-Butyl-6-fluoro-7- Substituted Naphthyridones.

R. Kessler, B. Ledoussal, J. Fung-Tomc, 1993 .

Structure-activity relationships of carbapenems that determine their dependence on porin protein D2 for activity against Pseudomonas aeruginosa

R. Kessler, J. Banville, M. Menard, 1995, Antimicrobial agents and chemotherapy.