Hua Xu

发表

Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis.

P. Tonge, Taesoo Kim, L. Bonnac, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors.

Peter J Tonge, P. Tonge, F. Johnson, 2008, Bioorganic & medicinal chemistry letters.

Mechanism and Regulation of Mycobactin Fatty Acyl-AMP Ligase FadD33*

J. Blanchard, O. Vergnolle, Hua Xu, 2013, The Journal of Biological Chemistry.

Synthesis and antitumor activity of formononetin nitrogen mustard derivatives.

Kun Hu, Jie Ren, Xin Chen, 2012, European journal of medicinal chemistry.

Reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP.

J. Blanchard, S. Hegde, Hua Xu, 2011, Biochemistry.

Synthesis and antitumor activity of liquiritigenin thiosemicarbazone derivatives.

Kun Hu, Jie Ren, Hua Xu, 2010, European journal of medicinal chemistry.

Metallic samarium and iodine promoted facile and efficient syntheses of trisubstituted alkenes from the acetates of Baylis–Hillman adducts

Yongming Zhang, Jian Li, Hua Xu, 2005 .

Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.

A. Tarun, P. Tonge, M. Zloh, 2013, Journal of natural products.

Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus.

Christopher F Stratton, T. Kirikae, P. Tonge, 2008, Biochemistry.

The complete genome of hydrocarbon-degrading Pseudoalteromonas sp. NJ289 and its phylogenetic relationship

Yi-bin Wang, Zhou Zheng, Hua Xu, 2017, Acta Oceanologica Sinica.

The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit

M. Voet, J. Blanchard, K. Severinov, 2020, Viruses.

Kinetic characterization of hydrolysis of nitrocefin, cefoxitin, and meropenem by β-lactamase from Mycobacterium tuberculosis.

J. Blanchard, Hua Xu, C. Chow, 2013, Biochemistry.

Kinetic Characterizations of Nitrocefin, Cefoxitin, and Meropenem Hydrolysis by β -lactamase from Mycobacterium tuberculosis

J. Blanchard, Hua Xu, C. Chow, 2013 .

Structures of the Michaelis complex (1.2 Å) and the covalent acyl intermediate (2.0 Å) of cefamandole bound in the active sites of the Mycobacterium tuberculosis β-lactamase K73A and E166A mutants.

J. Blanchard, Hua Xu, L. Tremblay, 2010, Biochemistry.

Acetylation of acetyl-CoA synthetase from Mycobacterium tuberculosis leads to specific inactivation of the adenylation reaction.

J. Blanchard, T. Noy, Hua Xu, 2014, Archives of biochemistry and biophysics.

NXL104 irreversibly inhibits the β-lactamase from Mycobacterium tuberculosis.

J. Blanchard, Hua Xu, Saugata Hazra, 2012, Biochemistry.

Post-translational Acetylation of MbtA Modulates Mycobacterial Siderophore Biosynthesis*

W. Jacobs, J. Blanchard, O. Vergnolle, 2016, The Journal of Biological Chemistry.

A Scalable Total Synthesis of Halofuginone

Fayang G. Qiu, Hua Xu, Yehua Jin, 2019, Organic Process Research & Development.

Tebipenem, a New Carbapenem Antibiotic, Is a Slow Substrate That Inhibits the β-Lactamase from Mycobacterium tuberculosis

J. Blanchard, Hua Xu, Saugata Hazra, 2014, Biochemistry.

A Novel Interaction Linking the FAS-II and Phthiocerol Dimycocerosate (PDIM) Biosynthetic Pathways*

P. Tonge, Nicole A. Kruh, B. Ruzsicska, 2008, Journal of Biological Chemistry.

Design, synthesis, and SAR study of novel 4,5-dihydropyrazole-Thiazole derivatives with anti-inflammatory activities for the treatment of sepsis.

Jihong Han, Xiaoxiao Yang, Yajun Duan, 2021, European journal of medicinal chemistry.

Total Synthesis of Entecavir: A Robust Route for Pilot Production

F. Wang, Fayang G. Qiu, Hua Xu, 2018 .

Reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP.

J. Blanchard, S. Hegde, Hua Xu, 2011, Biochemistry.

Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors.

P. Tonge, F. Johnson, R. Slayden, 2008, Bioorganic & medicinal chemistry letters.