S. Sachdeva

Interactions of mtFabH with its Substrates and Inhibitors Reveal Novel Mechanistic Insights

S. Sachdeva, 2007 .

Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates.

K. Reynolds, F. Musayev, H. Wright, 2008, Bioorganic chemistry.

Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A.

K. Reynolds, F. Musayev, J. N. Scarsdale, 2005, Journal of molecular biology.

Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes.

K. Reynolds, F. Musayev, H. Wright, 2007, Chemistry and Biology.

Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors.

N. Waters, K. Reynolds, Kevin A Reynolds, 2008, Bioorganic & medicinal chemistry letters.

Characterization of a two-component system, devR-devS, of Mycobacterium tuberculosis.

V. Kapur, J. Tyagi, T. Das, 2000, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Separate entrance and exit portals for ligand traffic in Mycobacterium tuberculosis FabH.

K. Reynolds, F. Musayev, H. Wright, 2008, Chemistry & biology.