W. Clarke

发表

Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists.

M. D. Hill, J. Macor, Yulia Benitex, 2017, ACS medicinal chemistry letters.

Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity.

Chiehying Y Chang, M. Gottardis, R. Attar, 2005, Journal of medicinal chemistry.

Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors: SAR of a series of 3-[6-(4-substituted-piperazin-1-yl)-4-methyl-1H-benzimidazol-2-yl]-1H-pyridine-2-one.

G. Trainor, M. Gottardis, A. Greer, 2010, Bioorganic & medicinal chemistry letters.

Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130

T. Molski, R. Mattson, N. Lodge, 2005, Pharmacology Biochemistry and Behavior.

Dihydropyridine neuropeptide Y Y1 receptor antagonists 2. bioisosteric urea replacements.

Scott W. Martin, I. Antal-Zimanyi, J. Romine, 2004, Bioorganic & medicinal chemistry.

Discovery and evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an orally efficacious inhibitor of insulin-like growth factor-1 receptor kinase with broad spectrum in vivo antitumor activ

Zheng Yang, Sean Kim, Praveen Balimane, 2008, Journal of medicinal chemistry.

Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with Curative Antitumor Activit

C. Fairchild, M. Deshpande, R. Kramer, 2004 .

Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors.

J. Macor, K. Kish, V. Arora, 2016, Journal of medicinal chemistry.

BMS-345541 Is a Highly Selective Inhibitor of IκB Kinase That Binds at an Allosteric Site of the Enzyme and Blocks NF-κB-dependent Transcription in Mice*

James R. Burke, John F. MacMaster, K. McIntyre, 2003, The Journal of Biological Chemistry.

Synthesis and evaluation of 5,5-diphenylimidazolones as potent human neuropeptide Y5 receptor antagonists.

Astrid A. Ortiz, I. Antal-Zimanyi, S. Rassnick, 2006, Bioorganic & medicinal chemistry.

Design and synthesis of 4-heteroaryl 1,2,3,4-tetrahydroisoquinolines as triple reuptake inhibitors.

J. Macor, Shuang Liu, T. Molski, 2014, ACS medicinal chemistry letters.

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.

K. McIntyre, Y. Qiu, F Christopher Zusi, 2003, The Journal of biological chemistry.

BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.

J. Macor, Yulia Benitex, D. Post‐Munson, 2017, ACS medicinal chemistry letters.

Synthesis and structure–activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-β inhibitors

K. McIntyre, K. Gillooly, M. Belema, 2007 .

Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects

H. Soares, J. Macor, M. Ahlijanian, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Design, Structure-Activity Relationships, and In Vivo Evaluation of Potent and Brain-Penetrant Imidazo[1,2-b]pyridazines as Glycogen Synthase Kinase-3β (GSK-3β) Inhibitors.

Vijay T. Ahuja, J. Macor, K. Kish, 2023, Journal of medicinal chemistry.

Discovery of a Novel Class of Bicyclo[3.1.0]hexanylpiperazines as Noncompetitive Neuropeptide Y Y1 Antagonists.

Astrid A. Ortiz, O. Flint, M. Deshpande, 2012, ACS medicinal chemistry letters.

A potential 5-HT1A receptor antagonist: p-MPPI.

H. Kung, M. Kung, Z. Zhuang, 1994, Life sciences.

Synthesis of (+)-(R)- and (-)-(S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)] aminotetralin: new 5-HT1A receptor ligands.

H. Kung, M. Kung, M. Mu, 1995, Chirality.

Synthesis and structure-activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-beta inhibitors.

K. McIntyre, K. Gillooly, M. Belema, 2007, Bioorganic & Medicinal Chemistry Letters.

Discovery of 2-(Anilino)pyrimidine-4-carboxamides as Highly Potent, Selective, and Orally Active Glycogen Synthase Kinase-3 (GSK-3) Inhibitors.

Vijay T. Ahuja, J. Tokarski, J. Macor, 2023, Journal of medicinal chemistry.

BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.

J. Macor, Yulia Benitex, D. Post‐Munson, 2017, ACS medicinal chemistry letters.